8 papers · ranked by Valyu relevance
Luca Minati, Claudia Firrito, Alessia Del Piano, Alberto Peretti + 12 more
A vast portion of the mammalian genome is transcribed as long non-coding RNAs (lncRNAs) acting in the cytoplasm with largely unknown functions. Surprisingly, lncRNAs have been shown to interact with ribosomes, encode uncharacterized proteins, or act as ribosome sponges. These functions still remain mostly undetected…
Maxfield M.G. Kelsey, Radha L. Kalekar, John M. Sedivy
Cellular senescence drives aging-related tissue dysfunction through the senescence-associated secretory phenotype (SASP), an inflammatory secretome linked to retrotransposable element (RTE) derepression. Transcriptomic and proteomic approaches have extensively characterized the senescence program, but key gaps remain…
Luca Minati, Claudia Firrito, Alessia Del Piano, Alberto Peretti + 14 more
'Simone Sidoli' 'Daniele Peroni' 'Romina Belli' 'Francesco Gandolfi' 'Alessandro Romanel' 'Paola Bernabo' 'Jacopo Zasso' 'Alessandro Quattrone' 'Graziano Guella' 'Fabio Lauria' 'Gabriella Viero' 'Massimiliano Clamer' 'Howard Y Chang' 'James L Manley'] A vast portion of the mammalian genome is transcribed as long…
Jiro Kato, Sachiko Yamashita, Hiroko Ishiwata-Endo, Shunya Oka + 10 more
ADP-ribosylation is a reversible reaction with ADP-ribosyltransferases catalyzing the forward reaction and ADP-ribose-acceptor hydrolases (ARHs) hydrolyzing the ADP-ribose acceptor bond. ARH2 is a member of the 39-kDa ARH family (ARH1-3), which is expressed in heart and skeletal muscle. ARH2 failed to exhibit any in…
Bent Larsen Petersen, Cora A. MacAlister, Peter Ulvskov
A wide range of proteins with diverse functions in development, defense, and stress responses are O-arabinosylated at hydroxyprolines (Hyps) within distinct amino acid motifs of continuous stretches of Hyps, as found in the structural cell wall extensins, or at non-continuous Hyps as, for example, found in small…
Markus Blaukopf, Bernhard Müller, Andreas Hofinger, Paul Kosma
Disaccharides that contain 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) and d-glycero-d-talo-oct-2-ulosonic acid (Ko) substituted at the 8-position by 4-amino-4-deoxy-β-l-arabinopyranosyl (Ara4N) residues have been prepared. Coupling an N-phenyltrifluoroacetimidate-4-azido-4-deoxy-l-arabinosylglycosyl donor to…
Andrea Toaiari, Federico Cunico, Xiangmin Xu, Haralambos Dafas + 3 more
Perspective: The HARPER Dataset Authors: ['Andrea Toaiari' 'Federico Cunico' 'Xiangmin Xu' 'Haralambos Dafas' 'Alessandro Vinciarelli' 'Liying Li' 'Marco Cristani'] Abstract— We introduce HARPER, a novel dataset for 3D body pose estimation and forecast in dyadic interactions between users and Spot, the quadruped robot…
Joey L. Galindo, Philip D. Jeffrey, Angela Zhu, A. James Link + 1 more
The Acetivibrio thermocellus DSM1313 genome codes for seven predicted glycoside hydrolase family 43 (GH43) enzymes, four of which remain uncharacterized. This study describes the function and structure of one such enzyme, AtAbf43C, from GH43 subfamily 26 (GH43_26) which acts as an ⍺-L-arabinofuranosidase (EC 3.2.1.55).…