25 papers · ranked by Valyu relevance
Sigurbjörn Markússon, Erik I. Hallin, Helene J. Bustad, Arne Raasakka + 6 more
Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral origin with a vital role in the regulation of synaptic plasticity and memory formation in mammals. However, the mechanistic and structural basis of Arc function is little understood. Arc has an NTD involved in membrane…
Craig Myrum, Jonathan Soulé, Margarethe Bittins, Kyle Cavagnini + 7 more
'Kevin Goff' 'Silje K. Ziemek' 'Maria S. Eriksen' 'Sudarshan Patil' 'Adrian Szum' 'Rajeevkumar R. Nair' 'Clive R. Bramham'] Activity-regulated cytoskeleton-associated protein, Arc, is a major regulator of long-term synaptic plasticity and memory formation. Here we reveal a novel interaction partner of Arc, a resident…
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid + 10 more
The Activity-Regulated Cytoskeleton-Associated protein (Arc), is pivotal to mediate plasticity responses in neuronal cells. In vitro studies suggest its ability to form high- and low-order oligomers, which are involved in neuronal trafficking. Despite its important functions, no direct observation of Arc oligomers in…
José M. Godoy Muñoz, Lasse Neset, Sigurbjörn Markússon, Sarah Weber + 6 more
The activity-regulated cytoskeleton-associated protein (Arc) is a complex regulator of synaptic plasticity in glutamatergic neurons. Understanding its molecular function is key to elucidate the neurobiology of memory and learning, stress regulation, and multiple neurological and psychiatric diseases. The recent…
José M. Godoy Muñoz, Lasse Neset, Sigurbjörn Markússon, Sarah Weber + 7 more
'Oda C. Krokengen' 'Aleksi Sutinen' 'Eleni Christakou' 'Andrea J. Lopez' 'Clive R. Bramham' 'Petri Kursula' 'Parvez Alam'] The activity-regulated cytoskeleton-associated protein (Arc) is a complex regulator of synaptic plasticity in glutamatergic neurons. Understanding its molecular function is key to elucidate the…
Yuta Ishizuka, Tadiwos F. Mergiya, Rodolfo Baldinotti, Ju Xu + 4 more
Activity-regulated cytoskeleton-associated (Arc) protein plays key roles in long-term synaptic plasticity, memory, and cognitive flexibility. However, an integral understanding of Arc mechanisms is lacking. Arc is proposed to function as an interaction hub in neuronal dendrites and the nucleus, yet Arc can also form…
Sigurbjörn Markússon, Erik I. Hallin, Helene J. Bustad, Arne Raasakka + 7 more
Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral origin with a vital role in the regulation of synaptic plasticity and memory formation in mammals. However, the mechanistic and structural basis of Arc function is poorly understood. Arc has an N-terminal domain (NTD)…
Yuta Ishizuka, Tadiwos F. Mergiya, Rodolfo Baldinotti, Ju Xu + 4 more
'Erik I. Hallin' 'Sigurbjörn Markússon' 'Petri Kursula' 'Clive R. Bramham'] Activity-regulated cytoskeleton-associated (Arc) protein plays key roles in long-term synaptic plasticity, memory, and cognitive flexibility. However, an integral understanding of Arc mechanisms is lacking. Arc is proposed to function as an…
Tadiwos F. Mergiya, Jens Edvard Trygstad Gundersen, Tambudzai Kanhema, Grant Brighter + 2 more
'Grant Brighter' 'Yuta Ishizuka' 'Clive R. Bramham'] The immediate early gene product activity-regulated cytoskeleton-associated protein (Arc or Arg3.1) is a major regulator of long-term synaptic plasticity with critical roles in postnatal cortical development and memory formation. However, the molecular basis of Arc…
Maria Steene Eriksen, Oleksii Nikolaienko, Erik Ingmar Hallin, Sverre Grødem + 18 more
Expression of activity-regulated cytoskeleton-associated protein (Arc) is critical for long-term synaptic plasticity, memory formation, and cognitive flexibility. The ability of Arc to self-associate and form virus-like capsid structures implies functionally distinct oligomeric states. However, the molecular mechanism…
M. Meneghetti, Matthias Bartelmann, H. Dahle, Marceau Limousin
The existence of an arc statistics problem was at the center of a strong debate in the last fifteen years. With the aim to clarify if the optical depth for giant gravitational arcs by galaxy clusters in the so called concordance model is compatible with observations, several studies were carried out which helped to…
Yu-Yuan Wang, Shih-Hsin Hsu, Hsin-Yao Tsai, Fu-Yu Cheng + 2 more
Arc/Arg3.1 (activity-regulated cytoskeletal-associated protein (ARC)) is a critical regulator of long-term synaptic plasticity and is involved in the pathophysiology of schizophrenia. The functions and mechanisms of human ARC action are poorly understood and worthy of further investigation. To investigate the function…
Per Niklas Hedde, Leonel Malacrida, Barbara Barylko, Derk D. Binns + 2 more
'Joseph P. Albanesi' 'David M. Jameson'] The activity-regulated cytoskeletal-associated protein (Arc, also known as Arg3.1) is an immediate early gene product induced by activity/experience and required for multiple modes of synaptic plasticity. Both long-term potentiation (LTP) and long-term depression (LTD) are…
Yu Li, Rencheng Zhang, Kai Yang, Yufan Qi + 1 more
The magnetohydrodynamics (MHD) model of the alternating current (AC) arc is complex, so a simplified equivalent heat source (EHS) model can be used to replace the complex model in studying the AC arc’s thermal characteristics and cable fire risk. A 2D axisymmetric AC arc MHD simulation model in the short gap of a…
Aya Al Othman, Dmitry Bagrov, Julian Rozenberg, Olga Glazova + 3 more
Activity-regulated cytoskeleton-associated (Arc) protein is expressed in neural tissue of vertebrates, where it plays a pivotal role in modulation of synaptic communication mediating AMPA receptor trafficking and actin cytoskeletal dynamics in dendritic spines. In addition, Arc protein forms capsid-like particles…
V. Vekselman, Matthew Feurer, Ting Huang, B. Stratton + 1 more
'Yevgeny Raitses'] Comprehensive non-invasive spectroscopic techniques and electrical measurements of the carbon arc revealed two distinguishable plasma synthesis regions in the radial direction normal to the arc axis. These regions, which are defined as the arc core and the arc periphery, are shown to have very…
Akio Kawauchi
It is shown that the projection image of an oriented spatial arc to any oriented plane is approximated by a unique arc diagram (up to isomorphic arc diagrams) determined from the spatial arc and the projection. In a separated paper, the knotting probability of an arc diagram is defined as an invariant under isomorphic…
Authors not listed
In-liquid plasma electrolysis refers to the ignition of a plasma in a thin vapor layer surrounding a solid electrode immersed in a liquid electrolyte and its associated processes. Over the last century, this phenomenon has been described under various names and is frequently denoted as Contact Glow Discharge…
E. Hatziminaoglou, M. A. Zwaan, P. Andreani, M. Bárta + 14 more
'J. Brand' 'Frederique Gueth' 'M. R. Hogerheijde' 'Matthias Maercker' 'M. Massardi' 'Stefanie Muehle' 'Thomas W B Muxlow' 'Anita Richards' 'P. Schilke' 'R. P. J. Tilanus' 'W. H. T. Vlemmings' 'J. Afonso' 'Hugo Messias'] - Evanthia Hatziminaoglou1 Martin Zwaan1 Paola Andreani1 Miroslav Barta2 Frank Bertoldi3 Jan Brand4…
Gustavo Madeira, S. M. Giuliatti Winter
> Abstract. Ring arcs are the result of particles in corotation resonances with nearby satellites. Arcs are present in Saturn and Neptune systems, in Saturn they are also associated with small satellites immersed on them. The satellite Aegaeon is immersed in the G ring arc, and the satellites Anthe and Methone are…
Patrik Nystedt
One of the first experiences of measurements that we encounter in our lives is that of length. Even young children are involved in many everyday activities that concern length measurements. Questions such as "How tall am I?" or "How long can you jump?" or "How far is it to my friends house?" arise naturally from them.…
Authors not listed
Transition-state (TS) identification for bimolecular liquid-phase reactions is notoriously sensitive to the initial spatial arrangement of reactants, making automated searches difficult, especially in solvation where conformational effects dominate barrier heights. We address this gap with a fully automated, heuristic…
Authors not listed
Efficient synthetic methods are urgently needed to produce graphene nanoribbons (GNRs) with diverse structures and functions. Precise control over the topological edges of GNRs is also crucial for achieving diverse molecular topologies and desirable electro-optical properties. This study demonstrates a highly efficient…
Suresh Balaji Srinivasan, Sangamithirai Devendiran, Kirankumar Venkatesan Savunthari, Pandurangan Arumugam + 1 more
Chemically doped carbon-based candidates have emerged as a significant driving force across multifarious research domains including ORR, electrochemical sensing, Energy storage and conversion, and solar cell technologies, etc., This comprehensive review takes a critical stance, shedding light on the exceptional…
Authors not listed
Curried functions provide a systematic way of transforming multi-argument functions into nested singleargument functions. This transformation allows partial application and supports many central principles of functional programming. Their extension, called curried 𝑘-ary functions, naturally generalizes the familiar…