14 papers · ranked by Valyu relevance
Brian Sutton, Supriyo Datta
The use of spin torque as a substitute for magnetic fields is now well established for classical operations like the switching of a nanomagnet. What we are describing here could be viewed as an application of spin torque like effects to quantum processes involving single qubit rotations as well as two qubit…
Ping Zhou, Li Lv
Implementing CNOT operation nonlocally is one of central tasks in distributed quantum computation. Most of previously protocols for implementation quantum CNOT operation only consider implement CNOT operation in one degree of freedom(DOF). In this paper, we present a scheme for nonlocal implementation of hyper-parallel…
Dohun Kim, Minyoung Kim, Sarah Meng Li, Michele Mosca
We introduce an improved CNOT synthesis algorithm that considers nearest-neighbour interactions and CNOT gate error rates in noisy intermediate-scale quantum (NISQ) hardware. Compared to IBM's Qiskit compiler, it improves the fidelity of a synthesized CNOT circuit by about 2 times on average (up to 9 times). It lowers…
Kai Xing, Rongbo Lu, Sihai Liu, Lu Lan + 1 more
This paper presents a semi-quantum secret sharing (SQSS) protocol based on three-particle W states, designed for efficient and secure secret sharing in quantum-resource-constrained scenarios. In the protocol, a fully quantum-capable sender encodes binary secrets using W, while receivers with limited quantum…
René M. Arvola, Chung-Te Chang, Joseph P. Buytendorp, Yevgen Levdansky + 3 more
Pumilio is an RNA-binding protein that represses a network of mRNAs to control embryogenesis, stem cell fate, fertility, and neurological functions in Drosophila. We sought to identify the mechanism of Pumilio-mediated repression and find that it accelerates degradation of target mRNAs, mediated by three N-terminal…
Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima + 3 more
Liver development involves dramatic gene expression changes mediated by transcriptional and post-transcriptional control. Here, we show that the Cnot deadenylase complex plays a crucial role in liver functional maturation. The Cnot3 gene encodes an essential subunit of the Cnot complex. Mice lacking Cnot3 in liver have…
Irfansha Shaik, Jaco van de Pol
CNOT optimization plays a significant role in noise reduction for Quantum Circuits. Several heuristic and exact approaches exist for CNOT optimization. In this paper, we investigate more complicated variations of optimal synthesis by allowing qubit permutations and handling layout restrictions. We encode such problems…
Alfonso Rodríguez-Gil, Olesja Ritter, Vera V. Saul, Jochen Wilhelm + 6 more
'Chen-Yuan Yang' 'Rudolf Grosschedl' 'Yumiko Imai' 'Keiji Kuba' 'Michael Kracht' 'M. Lienhard Schmitz'] The multi-subunit CCR4 (carbon catabolite repressor 4)-NOT (Negative on TATA) complex serves as a central coordinator of all different steps of eukaryotic gene expression. Here we performed a systematic and…
Isioma I.I. Enwerem, Nathan D. Elrod, Chung-Te Chang, Ai Lin + 6 more
Pumilio paralogs, PUM1 and PUM2, are sequence-specific RNA-binding proteins that are essential for vertebrate development and neurological functions. PUM1&2 negatively regulate gene expression by accelerating degradation of specific mRNAs. Here, we determined the repression mechanism and impact of human PUM1&2 on the…
Hoon Ryu, Ji-Hoon Kang
The quality of quantum bits (qubits) in silicon is highly vulnerable to charge noise that is omnipresent in semiconductor devices and is in principle hard to be suppressed. For a realistically sized quantum dot system based on a silicon-germanium heterostructure whose confinement is manipulated with electrical biases…
Dmitry V. Zakablukov
| Ф. Э. | — | функциональный элемент | | --- | --- | --- | | NOT | — | инвертор | | Nn t | — | инвертор c n входами, t — контролируемый выход | | Nt | — | инвертор, t — контролируемый выход | | CNOT | — | управляемый инвертор | | n C i;t | — | управляемый инвертор с n входами, t — контролируемый выход, | | | | i —…
Sunit Pal, Ilja Gordijenko, Stefan Schmeing, Somarghya Biswas + 3 more
The removal of poly(A) tail from mRNA sequences reduces their stability and translational activity. The deadenylation process is mainly regulated by the CCR4-NOT complex for which potent chemical inhibitors are rare. The subunit NOT9 binds various RNA binding proteins (RBPs) which recruit mRNA in a sequence-specific…
Xu Zhang, Roman Vlkolinsky, Chongyang Wu, Nima Dolatabadi + 8 more
CREB-regulated transcription coactivator 1 (CRTC1) plays an important role in synaptic plasticity, learning and long-term memory formation through regulation of neuronal activity-dependent gene expression, and CRTC1 dysregulation is implicated in Alzheimer’s disease (AD). Here, we show that increased S-nitrosylation of…
Weiman Yuan, Can Luo, Yunfei Hu, Liting Zhang + 4 more
Single-cell DNA sequencing (scDNA-seq) resolves copy number variation (CNV) at single-cell resolution, revealing tumor heterogeneity and subclonal structure. Most existing methods, however, infer only total copy number. Haplotype-resolved copy number, which captures allelic imbalance and clonal evolution, remains far…