14 papers · ranked by Valyu relevance
Aparna Wagle Shukla, Pam Zeilman, Hubert Fernandez, Jawad A. Bajwa + 1 more
'Raja Mehanna'] Deep brain stimulation (DBS) surgery is a well-established therapy for control of motor symptoms in Parkinson's disease. Despite an appropriate targeting and an accurate placement of DBS lead, a thorough and efficient programming is critical for a successful clinical outcome. DBS programming is a time…
Carla Palleis, Mona Gehmeyr, Jan H. Mehrkens, Kai Bötzel + 1 more
'Thomas Koeglsperger'] Background: Deep brain stimulation (DBS) has become a standard treatment for advanced stages of Parkinson's disease, essential tremor, and dystonia. In addition to the correct surgical device implantation, effective programming is regarded to be the most important factor for clinical outcome.…
Anna Franziska Frigge, Alexander Medvedev
Brain Stimulation Authors: ['Anna Franziska Frigge' 'Alexander Medvedev'] Abstract— Deep brain stimulation (DBS) programming remains a complex and time-consuming process, requiring manual selection of stimulation parameters to achieve therapeutic effects while minimizing adverse side-effects. This study explores…
Jiaming Mei, Bowen Chang, Chi Xiong, Manli Jiang + 1 more
Objective: Programming plays an important role in the outcome of deep brain stimulation (DBS) for Parkinson's disease (PD). This study introduced a new application for functional zonal image reconstruction in programming. Methods Follow-up outcomes were retrospectively compared, including first programming time, number…
Sumedh S Nagrale, Ali Yousefi, Theoden I Netoff, Alik S Widge
Deep brain stimulation (DBS) of the ventral internal capsule/striatum (VCVS) is a potentially effective treatment for several mental health disorders when conventional therapeutics fail. Its effectiveness, however, depends on correct programming to engage VCVS sub-circuits. VCVS programming is currently an iterative…
Shengdi Chen, Guodong Gao, Tao Feng, Jianguo Zhang
Background Deep Brain Stimulation (DBS) therapy for the treatment of Parkinson’s Disease (PD) is now a well-established option for some patients. Postoperative standardized programming processes can improve the level of postoperative management and programming, relieve symptoms and improve quality of life. Main body In…
Chun Him Shelton Leung, Hugh D. Simpson, Dominic Thyagarajan, Allan Bieber
'Allan Bieber'] Background/Objections: The pharmacological management of Parkinson’s Disease (PD) is often supplemented by deep brain stimulation (DBS) to tackle problems of advanced disease such as motor fluctuation, dyskinesias or medication-resistant tremor. DBS uses high-frequency stimulation with spatially…
Grigoriev Evgeny
The problem of impedance mismatch between applications written in OO languages and relational DB is not a problem of discrepancy between object-oriented and relational approaches themselves. Its real causes can be found in usual implementation of the ОО approach. Direct comparison of the two approaches cannot be used…
Torsten Grust
We report on the conversion of two advanced database courses from their classical in-lecture-hall setup into an all-digital remote format that was delivered via YouTube. While the course contents were not turned on their heads, throughout the semester we adopted a video style that has been popularized by the live…
Joseph M. Hellerstein
This is a recollection of the UC Berkeley Postgres project, which was led by Mike Stonebraker from the mid-1980's to the mid-1990's. The article was solicited for Stonebraker's Turing Award book [Bro19], as one of many personal/historical recollections. As a result it focuses on Stonebraker's design ideas and…
Dimitri Yatsenko, Jacob Reimer, Alexander S. Ecker, Edgar Y. Walker + 6 more
The rise of big data in modern research poses serious challenges for data management: Large and intricate datasets from diverse instrumentation must be precisely aligned, annotated, and processed in a variety of ways to extract new insights. While high levels of data integrity are expected, research teams have diverse…
Authors not listed
Dried blood spots (DBS) offer a practical and relatively non-invasive method for sample collection. Here, we evaluate the feasibility of applying ¹H NMR spectroscopy to metabolomic analysis of DBS. Various solvent suppression techniques and extraction protocols were tested using aqueous and methanolic solvents.…
David H. Lorenz, Boaz Rosenan
Since the early days of the Web, web application developers have aspired to develop much of their applications declaratively. However, one aspect of the application, namely its business-logic is constantly left imperative. In this work we present Application Embedding, a novel approach to application development which…
Patience Motshosi, Bonolo B. Phinius, Mosimanegape Jongman, Kabo Baruti + 5 more
Dried blood spot (DBS) cards can be used as an alternative sample collection method to plasma, however, there is no optimized elution protocol for DBS cards specifically for hepatitis B surface antibody (anti-HBs) testing. The study aimed to develop a DBS elution protocol for anti-HBs quantification. Our study sought…