Search · four archives
Search · four archives
23 papers · ranked by Valyu relevance
Benjamin A. Neely, Paul M. Stemmer, Brian C. Searle, Laura E. Herring + 8 more
Despite the advantages of fewer missing values by collecting fragment ion data on all analytes in the sample, as well as the potential for deeper coverage, the adoption of data-independent acquisition (DIA) in core facility settings has been slow. The Association of Biomolecular Resource Facilities conducted a large…
Filip Buric, Jan Zrimec, Aleksej Zelezniak
High-throughput data-independent acquisition (DIA) is the method of choice for quantitative proteomics, combining the best practices of targeted and shotgun proteomics approaches. The resultant DIA spectra are, however, highly convolved and with no direct precursor-fragment correspondence, complicating the analysis of…
Jack Penny, Gunnar N. Schroeder, José A. Bengoechea, Ben C. Collins
Data independent acquisition (DIA or DIA/SWATH) mass spectrometry has emerged as a primary measurement strategy in the field of quantitative proteomics. diaPASEF is a recent adaptation that leverages trapped ion mobility spectrometry (TIMS) to improve selectivity and increase sensitivity. The complex fragmentation…
Denys Oliinyk, Hem Gurung, Zhenru Zhou, Kristin Leskoske + 2 more
Human leukocyte antigen class I (HLA-I) molecules present short peptide sequences from endogenous or foreign proteins to cytotoxic T cells. The low abundance of HLA-I peptides poses significant technical challenges for their identification and accurate quantification. While mass spectrometry (MS) is currently a method…
E. Aprile, J. Aalbers, K. Abe, F. Agostini + 161 more
'L. Althueser' 'B. Andrieu' 'E. Angelino' 'J. R. Angevaare' 'V. C. Antochi' 'D. Antón Martin' 'F. Arneodo' 'L. Baudis' 'A. Baxter' 'L. Bellagamba' 'R. Biondi' 'A. Bismark' 'E. J. Brookes' 'A. Brown' 'S. Bruenner' 'G. Bruno' 'R. Budnik' 'B. T. Khai' 'Ce Cai' 'J. M. R. Cardoso' 'D. Cichon' 'A.P. Cimental Chavez' 'D.…
Kapil Nichani, Steffen Uhlig, Bertrand Colson, Karina Hettwer + 7 more
Detection of food fraud and geographical traceability of ingredients is a continually sought goal for government institutions, producers, and consumers. Herein we explore the use of non-target high-resolution mass spectrometry approaches and demonstrate its utility through a particularly challenging case study – to…
Jannik Wuttke, Tim Kobelt, Jonas Winkelholz, Martin Lippmann + 2 more
Title: Graphical abstract
J. Urbán, J. Pipek, M. Hron, F. Janky + 3 more
'A. Duarte'] We present a complex data handling system for the COMPASS tokamak, operated by IPP ASCR Prague, Czech Republic [1]. The system, called CDB (Compass DataBase), integrates different data sources as an assortment of data acquisition hardware and software from different vendors is used. Based on widely…
Mengchun Li, Venkatesh Mallikarjun, Andrew Frey, Emmanuel Ogundimu + 1 more
Mass spectrometry-based label-free proteomics data often suffer from missing values, especially for low-abundance proteins or when a protein is completely absent in one condition. This makes it challenging to estimate fold changes reliably and perform downstream analyses. Traditional imputation methods often show…
Darko Hercog, Bojan Gergič
This paper presents a low-cost microcontroller-based data acquisition device. The key component of the presented solution is a configurable microcontroller-based device with an integrated USB transceiver and a 12-bit analogue-to-digital converter (ADC). The presented embedded DAQ device contains a preloaded program…
Authors not listed
A commercial QqTOF platform (ZenoTOF 7600 system) was modified to enable three fragmentation modes, collision induced dissociation (CID), electron activated dissociation (EAD) and ultraviolet photodissociation (UVPD) at 266 nm. 168 pesticides, which showed fragmentation in CID provides also EAD spectra. In the case of…
T. J. Buckley, J. M. Rukkers
At NBS a data acquisition system for a flow calorimeter which accommodates large samples has been developed. The system is based on an instrument controller, scanners, and voltmeters, all available commercially. Detectors for temperature, gas flow rate, pressure, and gas chemical composition provide data on key…
Nathan Andreani Netzel, Daniel Strufaldi Batista, Francisco Granziera Jr., Marcelo Carvalho Tosin
Small sounding rockets often carry scientific instruments to collect data in atmospheric environments. In the context of university-level education and research, their development offers students a hands-on, multidisciplinary platform to study propulsion, aerodynamics, electronic instrumentation, and others. A critical…
Mircea Bogdan, E. Oberla, Henry J. Frisch, M. Wetstein
—We describe a modular multi-channel data acquisition system based on the 5-15 Gigasample-per-second waveformrecording PSEC4 chip. The system architecture incorporates two levels of hardware with FPGA-embedded system control and inline data processing. The front-end unit is a 30-channel circuit board that holds five…
J. Kvasnicka
The data acquisition system (DAQ) for a highly granular analogue hadron calorimeter (AHCAL) for the future International Linear Collider is presented. The developed DAQ chain has several stages of aggregation and scales up to 8 million channels foreseen for the AHCAL detector design. The largest aggregation device…
D. Belver, J. Boix, E. Calvo, C. Cuesta + 10 more
'I. Gil‐Botella' 'S. Jiménez' 'C. Lastoria' 'T. Lux' 'I. Martín' 'J.J. Martínez' 'C. Palomares' 'J. Soto-Otón' 'Anamaria Verdugo'] Abstract—ProtoDUNE-DP is a 6×6×6 m3 liquid argon timeprojection-chamber operated at the CERN Neutrino Platform in 2019-2020 as a prototype of the Dual Phase concept for the DUNE Far…
Toma-Stefan Cezar, Marios Maroudas, Dieter Horns
High-throughput physics experiments require efficient and increasingly complex real-time processing. This paper presents a modular, software-defined platform combining high-bandwidth PCIe digitizers with consumer GPUs to achieve continuous, zero-dead-time data acquisition. Utilizing NVIDIA CUDA, the system provides a…
Nayeon Kim, Hyuk Jun Yoo, Daeho Kim, Heeseung Lee + 1 more
Autonomous laboratories hold great promise for accelerating material discovery but are often restricted by static, predefined experimental constraints. We present SPACESHIP, an AIdriven framework for dynamic, constraint-free exploration of synthesizable regions in chemical parameter spaces. SPACESHIP integrates…
Rens Baeyens, Joachim Denil, Jan Steckel, Dennis Laurijssen + 2 more
'Walter Daems' 'Jari Nurmi'] In this paper, a model-based firmware generator is presented towards complex sampling schemes. The framework is capable of automatically generating a fixed-rate Shannon-compliant acquisition scheme, as well as a variable-rate compressive sensing acquisition scheme. The generation starts…
Hannes Reichert, Lukas F. Lang, Kevin Rösch, Daniel Bogdoll + 5 more
'Konrad Doll' 'Bernhard Sick' 'Hans-Christian Reuss' 'Christoph Stiller' 'J. Marius Zöllner'] Abstract—Full-stack autonomous driving perception modules usually consist of data-driven models based on multiple sensor modalities. However, these models might be biased to the sensor setup used for data acquisition. This…
Christoph Scholl, Maximilian Spiegler, Klaus Ludwig, Bjoern M. Eskofier + 3 more
'Bjoern M. Eskofier' 'Andreas Tobola' 'Dario Zanca' 'Jari Nurmi'] The advancement of embedded sensor systems allowed the monitoring of complex processes based on connected devices. As more and more data are produced by these sensor systems, and as the data are used in increasingly vital areas of applications, it is of…
Authors not listed
Raman spectroscopy is an increasingly powerful and fast-growing analytical technique across diverse disciplines, from materials science and chemistry to biology and medicine, thanks to advances in Raman instrumentation and greatly supported by the flourishing of chemometrics and artificial intelligence (AI). However…
David Herrmann, Patrick Hodapp, Martin Starman, Pei-Chi Huang + 16 more
Analytical data in chemistry and other disciplines is usually generated in different formats and lacks common data and metadata standards that are necessary for a FAIR handling of research data. In the work presented herein, we describe a workflow that uses non-standardized, in some cases proprietary data formats from…