21 papers · ranked by Valyu relevance
Luiz Pessoa
What is the relationship between brain and behavior? The answer to this question necessitates characterizing the mapping between structure and function. The aim of this paper is to discuss broad issues surrounding the link between structure and function in the brain that will motivate a network perspective to…
Haijing Niu, Jinhui Wang, Tengda Zhao, Ni Shu + 2 more
'Satoru Hayasaka'] Background The human brain is a highly complex system that can be represented as a structurally interconnected and functionally synchronized network, which assures both the segregation and integration of information processing. Recent studies have demonstrated that a variety of neuroimaging and…
Shu-Hsien Chu, Keshab K. Parhi, Christophe Lenglet
A joint structural-functional brain network model is presented, which enables the discovery of function-specific brain circuits, and recovers structural connections that are under-estimated by diffusion MRI (dMRI). Incorporating information from functional MRI (fMRI) into diffusion MRI to estimate brain circuits is a…
Shreyas Harita, Davide Momi, Zheng Wang, John D. Griffiths
Resting-state functional magnetic resonance imaging (fMRI) is a powerful tool for exploring the brain’s functional organization. Functional connectivity (FC) is a commonly studied feature of fMRI data defined as the temporal correlation between activity patterns in pairs of brain regions. A major discovery of the past…
Nicholas B. Dadario, Bledi Brahimaj, Jacky Yeung, Michael E. Sughrue
The surgical management of brain tumors is based on the principle that the extent of resection improves patient outcomes. Traditionally, neurosurgeons have considered that lesions in “non-eloquent” cerebrum can be more aggressively surgically managed compared to lesions in “eloquent” regions with more known functional…
Zitong Zhang, Qawi K. Telesford, Chad Giusti, Kelvin O. Lim + 1 more
'Danielle S. Bassett'] Abstract Wavelet methods are widely used to decompose fMRI, EEG, or MEG signals into time series representing neurophysiological activity in fixed frequency bands. Using these time series, one can estimate frequency-band specific functional connectivity between sensors or regions of interest, and…
Jie Lisa Ji, Marjolein Spronk, Kaustubh Kulkarni, Grega Repovš + 2 more
Large-scale functional network map of the entire human brain Cortical networks based on multiband fMRI, recently-identified regions Subcortical extension of networks covering all subcortical structures Multiple quality assessments demonstrate robustness of functional networks Network atlas released as public resource…
Mahshid Fouladivanda, Kamran Kazemi, Habibollah Danyali, Ardalan Aarabi
'Ardalan Aarabi'] Network disruption during early brain development can result in long-term cognitive impairments. In this study, we investigated rich-club organization in resting-state functional brain networks in full-term neonates using a multiscale connectivity analysis. We further identified the most influential…
John D. Medaglia, Danielle S. Bassett
Network analyses in nervous system disorders involves constructing and analyzing anatomical and functional brain networks from neuroimaging data to describe and predict the clinical syndromes that result from neuropathology. A network view of neurological disease and clinical syndromes facilitates accurate quantitative…
Authors not listed
Molecular mechanisms governing initiation steps of the assembly of thousands of endogenous multi-protein complexes (EMCs) remain incompletely understood. Here, multiple lines of observations are reported reflecting the biological functions-aligned initiation sequence of hybrid assembly pathways (HAPs) of EMCs. HAPs…
Rebecca L. Jackson, Gina F. Humphreys, Grace E. Rice, Richard J. Binney + 1 more
Resting-state network research is extremely influential, yet the functions of many networks remain unknown. In part, this is due to typical (e.g., univariate) analyses testing the function of individual regions and not the full set of co-activated regions that form a network. Connectivity is dynamic and the function of…
Olaf Sporns
Understanding the brain represents one of the most profound and pressing scientific challenges of the 21st century. As brain data have increased in volume and complexity, the tools and methods of network science have become indispensable for mapping and modeling brain structure and function, for bridging scales of…
Timothy F. Boerger, Peter Pahapill, Alissa M. Butts, Elsa Arocho-Quinones + 2 more
In recent years, a paradigm shift in neuroscience has been occurring from “localizationism,” or the idea that the brain is organized into separately functioning modules, toward “connectomics,” or the idea that interconnected nodes form networks as the underlying substrates of behavior and thought. Accordingly, our…
Youjing Luo, Xianghong Meng, Guangyu Zhou, Jiali Zhou + 9 more
Neuroimaging studies of hemodynamic fluctuations have shown specific network-based organization of the brain at rest, yet the neurophysiological underpinning of these networks in human brain remain unclear. Here, we recorded resting-state activities of neuronal populations in the key regions of default mode network…
Lucas C. Breedt, Fernando A. N. Santos, Arjan Hillebrand, Liesbeth Reneman + 12 more
Executive functioning is a higher-order cognitive process that is thought to depend on a brain network organization facilitating network integration across specialized subnetworks. The frontoparietal network (FPN), a subnetwork that has diverse connections to other brain modules, seems pivotal to this integration, and…
Richard F. Betzel
Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in perspective and emphasis on distributed brain function has provided fundamental…
Salma Salhi, Youssef Kora, Gisu Ham, Hadi Zadeh Haghighi + 1 more
The underlying anatomical structure is fundamental to the study of brain networks and is likely to play a key role in the generation of conscious experience. We conduct a computational and graph-theoretical study of the human structural connectome incorporating a variety of subcortical structures including the…
Randy McIntosh, Sean Hill, Olaf Sporns
Consciousness and cognition are an increasing focus of theoretical and experimental research in neuroscience, leveraging the methods and tools of brain dynamics and connectivity. This Focus Feature brings together a collection of articles that examine the various roles of brain networks in computational and dynamic…
Jean Faber, Priscila Correia Antoneli, Guillem Via, Noemi S. Araújo + 2 more
In recent years, new and important perspectives were introduced in the field of neuroimaging with the emergence of the connectionist approach (Williams and Henson 2018). In this new context, it is important to know not only which brain areas are activated by a particular stimulus but, mainly, how these areas are…
William Hedley Thompson, Peter Fransson
It is well-known that the brain’s activity is organized into networks but it is unclear how many networks exist. Additionally, there is also a risk of ambiguity since different names for the same network are frequently reported in the literature. In this study, we employed a mass meta-analysis of fMRI data associated…
Jingnan Du, Lauren M. DiNicola, Peter A. Angeli, Noam Saadon-Grosman + 7 more
The human cerebral cortex is populated by specialized regions that are organized into networks. Here we estimated networks using a Multi-Session Hierarchical Bayesian sModel (MS-HBM) applied to intensively sampled within-individual functional MRI (fMRI) data. The network estimation procedure was initially developed and…