17 papers · ranked by Valyu relevance
Itamar Sela, Haim Ashkenazy, Kazutaka Katoh, Tal Pupko
Inference of multiple sequence alignments (MSAs) is a critical part of phylogenetic and comparative genomics studies. However, from the same set of sequences different MSAs are often inferred, depending on the methodologies used and the assumed parameters. Much effort has recently been devoted to improving the ability…
Davide Ceneda, Theresia Gschwandtner, Thorsten May, Silvia Miksch + 3 more
'Hans‐Jörg Schulz' 'Marc Streit' 'Christian Tominski'] Abstract—At VAST 2016, a characterization of guidance has been presented. It includes a definition of guidance and a model of guidance based on van Wijk's model of visualization. This note amends the original characterization of guidance in two aspects. First, we…
Arpit Narechania, Alex Endert, Atanu R. Sinha
Analysts Impacts Visual Data Preparation and Analysis Authors: ['Arpit Narechania' 'Alex Endert' 'Atanu R. Sinha'] The progress in generative Artificial Intelligence (AI) has fueled AI-powered tools like co-pilots and assistants to provision better guidance, particularly during data analysis. However, research on…
Wei Wang, Kevin J. Liu
The standard bootstrap method is used throughout science and engineering to perform general-purpose non-parametric resampling and re-estimation. Among the most widely cited and widely used such applications is the phylogenetic bootstrap method, which Felsenstein proposed in 1985 as a means to place statistical…
Christina Stoiber, Davide Ceneda, Markus Wagner, Victor Schetinger + 4 more
'Theresia Gschwandtner' 'Marc Streit' 'Silvia Miksch' 'Wolfgang Aigner'] Abstract—A typical problem in Visual Analytics (VA) is that users are highly trained experts in their application domains, but have mostly no experience in using VA systems. Thus, users often have difficulties interpreting and working with visual…
Xavier Bosch-Capblanch, John N. Lavis, Simon Lewin, Rifat Atun + 12 more
In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the challenges to developing such guidance.
Maheshya Weerasinghe, Aaron Quigley, Klen Čopič Pucihar, Alice Toniolo + 2 more
Experiential learning (ExL) is a well-known learning approach used in education, training, facilitation, coaching and organisational development . ExL refers to the process of learning through experience or "learning by doing". One of the most influential models in ExL is the Kolb's learning model . This model defines…
Davide Ceneda, Christopher Collins, Mennatallah El‐Assady, Silvia Miksch + 2 more
'Silvia Miksch' 'Christian Tominski' 'Alessio Arleo'] Abstract—Guidance can support users during the exploration and analysis of complex data. Previous research focused on characterizing the theoretical aspects of guidance in visual analytics and implementing guidance in different scenarios. However, the evaluation of…
Holger J Schünemann, Atle Fretheim, Andrew D Oxman
Background The World Health Organization (WHO), like many other organisations around the world, has recognised the need to use more rigorous processes to ensure that health care recommendations are informed by the best available research evidence. This is the first of a series of 16 reviews that have been prepared as…
Authors not listed
Recent advances in structural biology have led to the publica- tion of a wealth of high resolution x-ray crystallography and cryo-EM macromolecule structures, including many complexes with small molecules of interest for drug design. While it is com- mon to incorporate information from the atomic coordinates of these…
Trudy van der Weijden, Dunja Dreesens, Marjan J. Faber, Nanne Bos + 7 more
2## METHODS The National Health Care Institute of the Netherlands initiated and granted this 12-month development study that was composed of a literature review, a feasibility check and a consensus procedure. We took the position that we needed various types of input and processes to ensure a successful consensus…
Alex Odlum, Rosemary James, Audrey Mahieu, Karl Blanchet + 3 more
'Chiara Altare' 'Neha Singh' 'Paul Spiegel'] Background For humanitarian organisations to respond effectively to complex crises, they require access to up-to-date evidence-based guidance. The COVID-19 crisis has highlighted the importance of updating global guidance to context-specific and evolving needs in…
Sergio Mascetti, Lorenzo Picinali, Andrea Gerino, Dragan Ahmetovic + 1 more
'Cristian Bernareggi'] In the last years several solutions were proposed to support people with visual impairments or blindness during road crossing. These solutions focus on computer vision techniques for recognizing pedestrian crosswalks and computing their relative position from the user. Instead, this contribution…
Carl G. de Boer, John P. Ray, Nir Hacohen, Aviv Regev
Pooled CRISPR screens allow high-throughput interrogation of genetic elements that alter expression of a reporter gene readout. New computational methods are needed to model these data. We created MAUDE (Mean Alterations Using Discrete Expression) for quantifying the impact of guide RNAs on a target gene’s expression…
Mateo Reveiz, Myungjin Lee, Peter D. Kwong, Tongqing Zhou + 1 more
Glycans bound to glycoproteins mediate immune response, including antibody recognition and immune evasion. Previously, we developed an in silico tool GLYCO (GLYcan COverage) to quantify the glycan shielding of a protein surface, applying it to various studies. However, GLYCO lacks sufficient computational efficiency…
Paloma Herrera, Valentina Fajreldin, María Francisca Rodríguez, Patricia Kraemer + 7 more
'Patricia Kraemer' 'Carolina Mendoza' 'Ignacio Pineda' 'Pamela Burdiles' 'Marco Cornejo' 'Julio Villanueva' 'María Dolores Tohá' 'Alonso Carrasco-Labra'] Title: RESUMEN Objetivo. Caracterizar el proceso de implementación, barreras y facilitadores de recomendaciones basadas en evidencia en el contexto del desarrollo de…
Eric W Deutsch, Juan Antonio Vizcaíno, Andrew R Jones, Pierre-Alain Binz + 25 more
The Human Proteome Organization (HUPO) Proteomics Standards Initiative (PSI) has been successfully developing guidelines, data formats, and controlled vocabularies (CVs) for the proteomics community and other fields supported by mass spectrometry since its inception twenty years ago. Here we describe the general…