19 papers · ranked by Valyu relevance
Susanne Schaller, Johannes Weinberger, Raul Jimenez-Heredia, Martin Danzer + 3 more
'Martin Danzer' 'Rainer Oberbauer' 'Christian Gabriel' 'Stephan M. Winkler'] Background Today’s modern research of B and T cell antigen receptors (the immunoglobulins (IG) or antibodies and T cell receptors (TR)) forms the basis for detailed analyses of the human adaptive immune system. For instance, insights in the…
Pablo Porras, Elisabet Barrera, Alan Bridge, Noemi del-Toro + 23 more
'Gianni Cesareni' 'Margaret Duesbury' 'Henning Hermjakob' 'Marta Iannuccelli' 'Igor Jurisica' 'Max Kotlyar' 'Luana Licata' 'Ruth C. Lovering' 'David J. Lynn' 'Birgit Meldal' 'Bindu Nanduri' 'Kalpana Paneerselvam' 'Simona Panni' 'Chiara Pastrello' 'Matteo Pellegrini' 'Livia Perfetto' 'Negin Rahimzadeh' 'Prashansa Ratan'…
Noemi del Toro, Anjali Shrivastava, Eliot Ragueneau, Birgit Meldal + 25 more
'Birgit Meldal' 'Colin Combe' 'Elisabet Barrera' 'Livia Perfetto' 'Karyn How' 'Prashansa Ratan' 'Gautam Shirodkar' 'Odilia Lu' 'Bálint Mészáros' 'Xavier Watkins' 'Sangya Pundir' 'Luana Licata' 'Marta Iannuccelli' 'Matteo Pellegrini' 'Maria Jesus Martin' 'Simona Panni' 'Margaret Duesbury' 'Sylvain\xa0D Vallet' 'Juri…
N. del-Toro, M. Duesbury, M. Koch, L. Perfetto + 12 more
'D. Ochoa' 'O. Wagih' 'J. Piñero' 'M. Kotlyar' 'C. Pastrello' 'P. Beltrao' 'L. I. Furlong' 'I. Jurisica' 'H. Hermjakob' 'S. Orchard' 'P. Porras'] The current wealth of genomic variation data identified at nucleotide level presents the challenge of understanding by which mechanisms amino acid variation affects cellular…
Micol Bassanini, Simone Deparis, Sala, Francesco + 1 more
In this work, we introduce a self–adaptive implicit–explicit (IMEX) time integration scheme, named IMEX–RB, for the numerical integration of systems of ordinary differential equations (ODEs), arising from spatial discretizations of partial differential equations (PDEs) by finite difference methods. Leveraging the…
Angelamaria Cardone, Z. Jackiewicz, Hong Zhang, Adrian Sandu
For many systems of differential equations modeling problems in science and engineering, there are natural splittings of the right hand side into two parts, one non-stiff or mildly stiff, and the other one stiff. For such systems implicit-explicit (IMEX) integration combines an explicit scheme for the non-stiff part…
Orlando Moranchel, Maël Balanec, Baptiste Verron, Lucie Royer + 6 more
XerC and XerD are ubiquitous bacterial recombinases dedicated to chromosome dimer resolution. They add a crossover at a specific chromosomal site, dif, when activated by the FtsK cell division protein. Several integrative mobile elements exploiting Xer (IMEXs) have been reported. IMEXs hijack XerCD to integrate at dif…
Giuseppe Orlando, Sebastiano Boscarino, Giovanni Russo
asymptotically-accurate IMEX methods for the Euler equations with non-ideal gases Authors: ['Giuseppe Orlando' 'Sebastiano Boscarino' 'Giovanni Russo'] We present a quantitative comparison between two different Implicit-Explicit Runge-Kutta (IMEX-RK) approaches for the Euler equations of gas dynamics, specifically…
N del Toro, M Duesbury, M Koch, L Perfetto + 12 more
The current wealth of genomic variation data identified at the nucleotide level has provided us with the downstream challenge of understanding by which of amino acid variation effects cellular processes. These effects may manifest as distinct phenotypic differences between individuals or to the development of disease.…
Jehanzeb H. Chaudhry, James B. Collins, John N. Shadid
Implicit-Explicit (IMEX) schemes are widely used for time integration methods for approximating solutions to a large class of problems. In this work, we develop accurate a posteriori error estimates of a quantity-of-interest for approximations obtained from multi-stage IMEX schemes. This is done by first defining a…
Weifeng Zhao, Juntao Huang
In this paper, we develop a high order finite difference boundary treatment method for the implicit-explicit (IMEX) Runge-Kutta (RK) schemes solving hyperbolic systems with possibly stiff source terms on a Cartesian mesh. The main challenge is how to obtain the solutions at ghost points resulting from the wide stencil…
Rodolfo R. Rosales, Benjamin Seibold, David Shirokoff, Dong Zhou
This paper presents a new class of high order linear ImEx multistep schemes with large regions of unconditional stability. Unconditional stability is a desirable property of a time stepping scheme, as it allows the choice of time step solely based on accuracy considerations. Of particular interest are problems for…
Bhagyashree S. Joshi, Carlos de Lannoy, Mark Howarth, Sung Hyun Kim + 1 more
Understanding the structure of biomolecules is vital for deciphering their characteristics and roles in biological systems. While current structural analysis techniques like nuclear magnetic resonance and X-ray crystallography excel in many aspects, they fall short in capturing comprehensive single-molecule…
Andrea J. Radtke, Ifeanyichukwu U. Anidi, Leanne Arakkal, Armando Arroyo-Mejías + 54 more
'Armando Arroyo-Mejías' 'Rebecca T. Beuschel' 'Katy Börner' 'Colin J. Chu' 'Beatrice Clark' 'Menna R. Clatworthy' 'Jake Colautti' 'Joshua Croteau' 'Saven Denha' 'Rose Dever' 'Walderez O. Dutra' 'Sonja Fritzsche' 'Spencer Fullam' 'Michael Y. Gerner' 'Anita Gola' 'Kenneth J. Gollob' 'Jonathan M. Hernandez' 'Jyh Liang…
N. del-Toro, M. Duesbury, M. Koch, L. Perfetto + 12 more
'D. Ochoa' 'O. Wagih' 'J. Piñero' 'M. Kotlyar' 'C. Pastrello' 'P. Beltrao' 'L. I. Furlong' 'I. Jurisica' 'H. Hermjakob' 'S. Orchard' 'P. Porras'] Correction to: Nature Communications 10.1038/s41467-018-07709-6; published online 02 January 2019 In the original HTML version of this Article, the order of authors within…
Nils Eling, Julien Dorier, Sylvie Rusakiewicz, Robin Liechti + 17 more
Multiplexed imaging is increasingly used to study tissue architecture in health and disease. To investigate the cancer tumor microenvironment, typically either tissue micro-arrays or small patient cohorts are used to collect and process data. However, studies performed over the course of years, collecting data from…
Diego Ulisse Pizzagalli, Pau Carrillo-Barbera, Elisa Palladino, Kevin Ceni + 8 more
Studying the spatiotemporal dynamics of cells in living organisms is a current frontier in bioimaging. Intravital Microscopy (IVM) provides direct, long-term observation of cell behavior in living animals, from tissue to sub-cellular resolution. Hence, IVM has become crucial for studying complex biological processes in…
Authors not listed
Native mass spectrometry (nMS) is increasingly popular for studying intact protein quaternary structure. When coupled with ion mobility, which separates ions based on their size, charge, and shape, it provides additional structural information on the protein complex of interest. In this study, we present a novel…
Authors not listed
Ion transport in porous carbon electrodes underpins the performance of electrochemical energy-storage and separation technologies, yet exchange dynamics within heterogeneous pore networks remain difficult to quantify. Here, we present a rigorous analytical framework for extracting quantitative ion-exchange kinetics in…