22 papers · ranked by Valyu relevance
Satomi Hiya, Carolina Maldonado-Díaz, Jamie M Walker, Timothy E Richardson
Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is a neuropathologic entity characterized by transactive response DNA-binding protein of 43-kDa (TDP-43)-immunoreactive inclusions that originate in the amygdala and then progress to the hippocampi and middle frontal gyrus. LATE-NC…
Elizaveta Mikhailenko, Kia Colangelo, Jarno Tuimala, Mia Kero + 13 more
'Sara Savola' 'Anna Raunio' 'Eloise H Kok' 'Maarit Tanskanen' 'Mira Mäkelä' 'Henri Puttonen' 'Mikko I Mäyränpää' 'Darshan Kumar' 'Karri Kaivola' 'Anders Paetau' 'Pentti J Tienari' 'Tuomo Polvikoski' 'Liisa Myllykangas'] Title: Abstract Population-based cohort studies are essential for understanding the pathological…
Ling Wu, Tobilola Akingbade, Peter T. Nelson, Shih-Hsiu J. Wang + 1 more
Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a neurodegenerative disease marked by TDP-43 proteinopathy, affecting approximately one-third of individuals aged 80 and above. LATE neuropathological change (LATE-NC) is characterized by the accumulation of phosphorylated TDP-43 preferentially in the…
Alex Wesseling, Ismael L Calandri, Maud M A Bouwman, Niels Reijner + 8 more
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) refers to the aberrant accumulation of TDP-43 in the brains of ageing individuals either in isolation or in combination with neurodegenerative disease. LATE-NC is most commonly found in the amygdala and hippocampus and is associated…
Kathy Y Liu, Suzanne Reeves, Kirsty E McAleese, Johannes Attems + 3 more
'Paul Francis' 'Alan Thomas' 'Robert Howard'] LATE neuropathological change (LATE-NC) is associated with a dementia syndrome that clinically overlaps with Alzheimer’s disease. Liu et al. show that the combination of LATE-NC and Alzheimer’s disease is not associated with greater neuropsychiatric symptom burden than…
Charisse N. Winston, Sonal Sukreet, Haley Lynch, Virginia M.-Y. Lee + 3 more
Limbic predominant age related TDP-43 encephalopathy (LATE) is a recently characterized brain disease that mimics Alzheimer’s disease (AD) clinically. To date, LATE is difficult to diagnose antemortem using clinical information or biomarkers. Recent studies suggest concentrations of exosomal protein cargo derived from…
Timo Hopp, G. Budde, T. Kleine
The Mo and Ru isotopic compositions of meteorites and the bulk silicate Earth (BSE) hold important clues about the provenance of Earth's building material. Prior studies have argued that non-carbonaceous (NC) and carbonaceous (CC) meteorite groups together define a Mo-Ru 'cosmic' correlation, and that the BSE plots on…
Ana Leonor Figueiredo, Frédérique Maczkowiak, Caroline Borday, Patrick Pla + 3 more
PFKFB4 controls neural crest final specification and migration by regulation of AKT signaling or glycolysis. Neural crest (NC) specification comprises an early phase, initiating immature NC progenitors formation at neural plate stage, and a later phase at neural fold stage, resulting into functional premigratory NC…
F. Nimmo, T. Kleine, Alessandro Morbidelli, David Nesvorný
The nucleosynthetic isotope signatures of meteorites and the bulk silicate Earth (BSE) indicate that Earth consists of a mixture of "carbonaceous" (CC) and "non-carbonaceous" (NC) materials. We show that the fraction of CC material recorded in the isotopic composition of the BSE varies for different elements, and…
Sing Chen Yeo, Jacinda Tan, Clin K.Y. Lai, Samantha Lim + 5 more
A person’s preferred timing of nocturnal sleep (chronotype) has important implications for cognitive performance. Students who prefer to sleep late may have a selective learning disadvantage for morning classes due to inadequate sleep and circadian desynchrony. Here, (1) we tested whether late-type students perform…
Maile, Lisa, Hielscher, Kai-Steffen + 2 more
—Time-Sensitive Networking (TSN) is a set of standards that enables the industry to provide real-time guarantees for time-critical communications with Ethernet hardware. TSN supports various queuing and scheduling mechanisms and allows the integration of multiple traffic types in a single network. Network Calculus (NC)…
Fridolin Spitzer, Christoph Burkhardt, G. Budde, T. S. Kruijer + 2 more
'Alessandro Morbidelli' 'T. Kleine'] The fundamentally different isotopic compositions of non-carbonaceous (NC) and carbonaceous (CC) meteorites reveal the presence of two distinct reservoirs in the solar protoplanetary disk that were likely separated by Jupiter. However, the extent of material exchange between these…
Nils Dorsch, Fabian Kurtz, Christian Wietfeld
Information and Communication Technology (ICT) infrastructures play a key role in the evolution from traditional power systems to Smart Grids. Increasingly fluctuating power flows, sparked by the transition towards sustainable energy generation, become a major issue for power grid stability. To deal with this…
Martyna Lukoseviciute, Sarah Mayes, Tatjana Sauka-Spengler
Neural crest (NC) is a vertebrate-specific population of multipotent embryonic cells predisposed to particular derivatives along the anteroposterior (A-P) axis. While only cranial NC progenitors give rise to ectomesenchymal cell types, trunk NC is biased for neuronal cell fates. By integrating multimodal single-cell…
Jiayi Zhu, Jing Lin, Zelong Tian, Feng He + 1 more
Time-Sensitive Networking (TSN) is critical to deterministic communication in safety-critical domains, with formal verification such as Network Calculus (NC) serving as the cornerstone for schedulability guarantees. However, during automated configuration-space exploration, repeated schedulability analysis consumes…
Sarah Abdul-Wajid, Bradley L Demarest, H Joseph Yost
Neural crest cells migrate to the embryonic heart and transform into a small number of cardiomyocytes, but their functions in the developing and adult heart are unknown. Here, we map the fates of neural crest derived cardiomyocytes (NC-Cms) and genetically ablate them in embryogenesis in zebrafish. Specific NC-Cm…
Authors not listed
A water-free ionothermal synthesis of porous magnesium-imprinted nitrogen-doped carbon (Mg–NC) materials is introduced to prepare a platform material to investigate electrocatalytic structure-performance relations. Atomically dispersed Co- and Fe-NCs isomorphic to the pristine Mg-NCs are prepared by ion-exchange…
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Atomically precise silver nanoclusters (Ag NCs) offer unique opportunities to correlate structure and photo-physical properties, yet enhancing their photoluminescence emission remains challenging due to dominance of non-radiative decay pathways. Here, we report a ligand-engineering strategy to modulate the optical…
Kirankumar Venkatesan Savunthari, Pulia Venkatachalapathy Keerthivasan, Saravanan Ashok Vallal, Aswin kumar Anbalagan + 1 more
The nickel-rich layered Li[Ni0.8Co0.1Mn0.1]O2, popularly known as NCM811, is considered a high-performance cathode material in lithium-ion batteries (LIBs) due to its high specific capacity and energy density. However, because of its poor structural stability, it suffers from long-run performance in LIBs. The surface…
Authors not listed
Ligand-protected copper nanoclusters (Cu NCs) with atomic precision have emerged rapidly due to their fascinating structural architectures and versatile catalytic properties, making them ideal for investigating structure–activity relationships. Despite their potential, challenges such as stability issues and limited…
Authors not listed
This study involved the construction of M-(n,n)NC single-atom site catalyst models on armchair single-walled carbon nanotubes with different curvatures (n = 5, 6, 7, 8, 9, 10; M = Fe, Co, Ni, Cu, Ru, Rh, Pd, Ag, Os, Ir, Pt, Au.). Spin-polarized density functional theory (DFT) calculations were utilized to analyze the…
Bharat Tandon, Sofia A. Shubert-Zuleta, Delia J. Milliron
Doped metal oxide nanocrystals (NCs) attract immense attention because of their ability to exhibit a localized surface plasmon resonance (LSPR) that can be tuned extensively across the infrared region of the electromagnetic spectrum. LSPR tunability triggered through compositional and morphological changes during the…