8 papers · ranked by Valyu relevance
Mikael Lisak, Malin Nicklasson, Robert Palmason, Stina Wichert + 8 more
Relapse remains the leading cause of treatment failure after allogeneic stem cell transplantation (HCT) in acute myeloid leukemia (AML), yet predictors of late relapse remain poorly defined. We conducted a multicenter retrospective study including 388 patients with AML, representing a disease-specific cohort undergoing…
Leonhard Kowalczyk, Tobias Kowalczyk, Yile Huang, Maik Hintze + 6 more
The timing of functional hypothalamic responsiveness during embryogenesis remains incompletely defined. We examined hypothalamic activation in chicken embryos from embryonic day (ED) 12-17 following experimental stimulation consisting of a localized foot injection of paraformaldehyde (PFA) together with the associated…
Lingshe Meng, Jinfeng Yin, Yingyu Jiang, Aichun Cheng + 4 more
Background Evidence for alteplase 4.5-24 h after acute ischemic stroke (AIS) onset remains limited in routine practice. We examined associations between late-window intravenous thrombolysis (IVT) and discharge outcomes in selected patients. Methods We analyzed China Stroke Center Alliance patients arriving 4-23.5 h…
Maša Žarković, Christina Schindera, Nicolas Waespe, Daniel Trachsel + 4 more
Background Childhood cancer survivors (CCSs) are at risk of pulmonary late effects, but post-treatment lung function remains understudied. Current guidelines recommend screening only for symptomatic survivors treated with lung-damaging treatments. We evaluated pulmonary function, risk factors and respiratory symptoms…
Charles C. Kim, Meghan Kerrisk Campbell, Maximilien Burq, Aljaz Potocnik + 6 more
Blood-based biomarkers are transforming Alzheimer’s Disease (AD) diagnosis and staging. Recent multi-protein plasma panels accurately identify individuals with advanced Braak pathology, but whether these circulating biomarkers truly reflect the molecular remodeling underlying AD neuropathology remains unclear.…
Lilla Kovács, Péter Przemyslaw Ujma
Sleep and nutrition are cornerstones of health, with likely reciprocal links between the two. The bidirectional link between sleep and food intake has been extensively studied, however, this literature relies almost completely on interventional and epidemiological studies. In the current study, we studied this link…
Nedime Karakullukcu, Michal Scheibel, Natalie Prochazkova, Bohdana Hruskova + 5 more
Interictal epileptiform discharges (IEDs) and pathological high-frequency oscillations - (HFOs) are established biomarkers of epileptogenic tissue, but how their spatiotemporal evolution reflects epileptic network reorganization in neocortical epilepsy remains unclear. We investigated longitudinal IED and HFO dynamics…
Cassandra Rioux‐Couture, Pierre Grondin, Guillaume de Lafontaine
Studying historical dynamics and compositional changes of ecotones is essential for improving predictions of their responses to anthropogenic global change. However, the small size and geographic isolation of marginal ecotonal stands require retrospective analyses at the local scale. Here, we combine soil macrofossil…