26 papers · ranked by Valyu relevance
Adelina-Gabriela Niculescu, Cristina Chircov, Alexandra Cătălina Bîrcă, Alexandru Mihai Grumezescu + 2 more
'Alexandra Cătălina Bîrcă' 'Alexandru Mihai Grumezescu' 'Ida Genta' 'Bice Conti'] Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips…
Karen Melissa Lerin-Morales, Luis F. Olguín, Eva Mateo-Martí, María Colín-García + 2 more
'María Colín-García' 'Ranajay Saha' 'Alberto Vázquez-Salazar'] Microfluidic devices are small tools mostly consisting of one or more channels, with dimensions between one and hundreds of microns, where small volumes of fluids are manipulated. They have extensive use in the biomedical and chemical fields; however, in…
Sagar Regmi, Chetan Poudel, Rameshwar Adhikari, Kathy Qian Luo
Taking the life of nearly 10 million people annually, cancer has become one of the major causes of mortality worldwide and a hot topic for researchers to find innovative approaches to demystify the disease and drug development. Having its root lying in microelectronics, microfluidics seems to hold great potential to…
Larissa Araújo Oliveira Alves, John Hebert da Silva Felix, Antônio Átila Menezes Ferreira, Maria Tayane Barroso dos Santos + 3 more
of Micro- and Mesofluidic Systems Authors: ['Larissa Araújo\nOliveira Alves' 'John Hebert da Silva Felix' 'Antônio\nÁtila Menezes Ferreira' 'Maria Tayane Barroso dos Santos' 'Carlos Galvão da Silva' 'Larysse Maria Santiago de Castro' 'José Cleiton Sousa\ndos Santos'] Microfabrication technology has advanced scientific…
Authors not listed
The capacity to pattern biomolecules within microfluidic devices expands the scope of microfluidic technologies. In such patterned systems, surface-bound components remained localized, while the microfluidic network supplies reagents and removes waste products. This approach has enabled continuous protein expression…
Xingfeng Ma, Gang Guo, Xuanye Wu, Qiang Wu + 6 more
'Hua Zhang' 'Nan Shi' 'Yimin Guan' 'Nam-Trung Nguyen' 'Colin Dalton'] Microfluidics attracts much attention due to its multiple advantages such as high throughput, rapid analysis, low sample volume, and high sensitivity. Microfluidics has profoundly influenced many fields including chemistry, biology, medicine…
Nazek El‐Atab, Javier Chavarrio Canas, Muhammad M. Hussain
Microfluidics is a continuously growing field with potential not only in the fields of medical, chemical, and bioanalysis, but also in the domains of optics and information technology. Here, a pressure-driven 3D microfluidic chip is demonstrated with multiple logic Boolean functions. The presence and absence of fluid…
Rucha Natu, Luke Herbertson, Grazziela Sena, Kate Strachan + 2 more
'Suvajyoti Guha' 'Francis Lin'] In recent years, the U.S. Food and Drug Administration (FDA) has seen an increase in microfluidic medical device submissions, likely stemming from recent advancements in microfluidic technologies. This recent trend has only been enhanced during the COVID-19 pandemic, as…
Natalie Arkus
The ability to close channels in microfluidic devices and to re-open and re-close them on demand is of great use in experiments. There is already a well-known and well-used microfluidic valve mechanism for doing this [1, 2, 3]. However, multiple microfluidic layers are used to construct these valves, and multilayer…
Authors not listed
Understanding how plants respond to dynamic and spatially variable stimuli is a key goal in plant sciences. Traditional imaging methods often involve a trade-off between environmental control and spatial resolution, limiting their ability to capture real-time responses in high resolution. Microfluidic technology…
Olukayode Majekodunmi, Sara Hashmi
In suspension flows through microchannels with parallel walls, rigid particles form clogs that grow continuously in the upstream direction. However, introducing a slight taper to channel walls leads to a qualitatively different clogging mechanism. Clogs of rigid particles do not grow continuously in these tapered…
Andrzej Krześniak, Tomasz Gabler, Monika Janik, Marcin Koba + 2 more
Microfluidics provide unique possibilities to control tiny volumes of liquids and their composition. To effectively benefit from the advantages of microfluidic solutions they need to be supported by interrogation subsystems, at best also matching the miniature scale. In this work we combined with a microfluidic system…
Mohsen Annabestani, Sina Azizmohseni, Pouria Esmaeili-Dokht, Nahal Bagheri + 2 more
'Nahal Bagheri' 'Afarin Aghassizadeh' 'Mahdi Fardmanesh'] Abstract—Electroactive-Polymers (EAPs) are one of the best soft materials with great applications in active microfluidics. Ionic ones (i-EAPs) have more promising features for being appropriate candidates to use in active microfluidic devices. Here, as a case…
Silvia Tea Calzuola, Gwenyth Newman, Thomas Feaugas, Cécile M. Perrault + 5 more
Microfluidic devices with integrated membranes that enable control of mass transport in constrained environments have shown considerable growth over the last decade. Membranes are a key component in several industrial processes such as chemical, pharmaceutical, biotechnological, food, and metallurgy separation…
Aldrik H. Velders, Lisette van Lieshout, Erik A. T. Brienen, Benedict Diederich + 1 more
Microparticles are ubiquitous and span from living matter to microplastics to inorganic materials. Their detection and identification must be more accessible and time efficient. Microfluidic devices can filter microparticles from liquids, but fabricating microfluidics with lateral resolutions of a few tens of microns…
Kaustav A. Gopinathan, Avanish Mishra, Baris R. Mutlu, Jon F. Edd + 1 more
Microfluidics have enabled significant advances in molecular biology^1–3^, synthetic chemistry^4,5^, diagnostics^6,7^, and tissue engineering^8^. However, there has long been a critical need in the field to manipulate fluids and suspended matter with the precision, modularity, and scalability of electronic…
Ali Olyanasab, Zahra Meskar, Mohsen Annabestani, Ali Mousavi Shaegh + 1 more
'Mehdi Fardmanesh'] The need for rapid fabrication of microfluidic devices has become increasingly critical as microfluidics become part of biomedical sensors. Using Warp and Weft Wiring (WWW) of copper wires, this paper presents a novel low-cost method for rapid, self-aligned, bonding-free, and modifiable fabrication…
Mohsen Annabestani, Mahdi Fardmanesh
-- This paper provides a detailed review on applications of ionic electroactive polymer (i-EAP) soft actuators as active elements of microfluidic micropumps, microvalves, and micromixers. The related works that have so far been presented by various research groups in the field have been collected in this review, which…
Authors not listed
Hydrogen/deuterium exchange (HDX) methods for studying protein dynamics would benefit from millisecond-scale incubations to probe intrinsically disordered proteins, highly dynamic regions and conformation changes. Here we investigate droplet microfluidics for rapid mixing to trigger D2O labelling, uniform incubations…
Carel Fijen, Mattia Fontana, Serge G. Lemay, Klaus Mathwig + 1 more
Single-molecule detection schemes offer powerful means to overcome static and dynamic heterogeneity inherent to complex samples. Probing chemical and biological interactions and reactions with high throughput and time resolution, however, remains challenging and often requires surface-immobilized entities. Here…
Preksha Gupta, Ambili Mohan, Apurv Mishra, Atindra Nair + 6 more
Droplet microfluidics has emerged as a critical component of several high-throughput single cell analysis techniques in biomedical research and diagnostics. However, while there has been significant progress in the individual assays being developed, multi-parametric optical sensing of droplets and their encapsulated…
Andrew J. deMello
Andrew is currently Professor of Biochemical Engineering in the Department of Chemistry and Applied Biosciences at ETH Zürich. Prior to this he was Professor of Chemical Nanosciences and Head of the Nanostructured Materials and Devices Section in the Chemistry Department at Imperial College London. He obtained a 1st…
George M. Whitesides
Memberships and Fellowships. American Academy of Arts and Sciences, National Academy of Sciences, National Academy of Engineering, American Philosophical Society, Fellow of the American Association for the Advancement of Science, Fellow of the Institute of Physics, New York Academy of Sciences, World Technology…
Ninad Mehendale, Oshin Sharma, Claudy D’Costa, Debjani Paul
Pillar-based microfluidic sorting devices are preferred for isolation of rare cells due to their simple designs and passive operation. Dead-end pillar filters can efficiently capture large rare cells, such as, circulating tumor cells (CTCs), nucleated red blood cells (NRBCs), etc., but they get clogged easily. Cross…
Kinshuk Mitra, Brett C. Geiger, Preethi Chidambaram, Aaron P. Maharry + 2 more
'Aaron P. Maharry' 'Ronald X. Xu' 'Michael F. Tweedle'] Microfluidic biosensors have been utilized for sensing a wide range of antigens using numerous configurations. Bead based microfluidic sensors have been a popular modality due to the plug and play nature of analyte choice and the favorable geometry of spherical…
Jatin Panwar, Rahul Roy
Microfluidic impedance cytometry (MIC) provides a non-optical and label-free method for single cell detection and classification in microfluidics. However, the cleanroom intensive infrastructure required for MIC electrode fabrication limits its wide implementation in microfluidic analysis. To bypass the conventional…