15 papers · ranked by Valyu relevance
Kelly Rock, Odessa Addison, Vicki L. Gray, Robert M. Henshaw + 3 more
'Christopher Ward' 'Victoria Marchese' 'Peter Hauser'] Children with hematologic and oncologic health conditions are at risk of impaired skeletal muscle strength, size, and neuromuscular activation that may limit gross motor performance. A comprehensive assessment of neuromuscular function of these children is…
Matheus D. Pinto, James M. Wakeling, Javier A. Almonacid, Anthony J. Blazevich
Skeletal muscle architectural design strongly affects force-generating capacity and excursion range, and its functional importance to animal and human movement is well-founded. Traditionally, this ‘structure−function relation’ has been inferred when assessing a muscle’s architecture at rest, often using muscle images…
Anna E. Sprinchorn, Norman Eizenberg, Priscilla J. Barker
Background The fibularis longus (FL) muscle is larger in volume than fibularis brevis (FB) and is therefore claimed to be the stronger evertor of the two. Clinical observation of FL and FB tendon rupture show that injury to the FB has a serious negative effect on hindfoot eversion. This implies that the FB is the…
Edwin D.H.M. Reuvers, Huub Maas, Wendy Noort, Maarten F. Bobbert + 1 more
The average mechanical power output (AMPO) during a stretch-shortening cycle produced by a muscle depends on muscle length and stimulation over time. While the effects of cycle frequency and muscle length excursion on AMPO are well-known, several questions remain about the effects of muscle length and stimulation over…
Annika Kruse, Cintia Rivares, Guido Weide, Markus Tilp + 1 more
'Richard T. Jaspers'] Treatment strategies and training regimens, which induce longitudinal muscle growth and increase the muscles’ length range of active force exertion, are important to improve muscle function and to reduce muscle strain injuries in clinical populations and in athletes with limited muscle…
Eleftherios Kellis, Anthony J. Blazevich
Temporal biomechanical and physiological responses to physical activity vary between individual hamstrings components as well as between exercises, suggesting that hamstring muscles operate differently, and over different lengths, between tasks. Nevertheless, the force-length properties of these muscles have not been…
Jiaxiang Xu, Bin Chen
Contradictory experimental reports on the relationship between efficiency and stimulation frequency have hindered mechanistic understanding in converting neural activity into mechanical work during muscle contraction. To resolve this issue, we develop a biophysical model integrating calcium-mediated excitation with a…
Zhenhao Liu, Phoebe Duncombe, Vitaly Napadow, Geoffrey Handsfield
Physiological cross-sectional area (PCSA) is defined as the summed cross-sectional area of all muscle fibers contracting in parallel and at optimal length. PCSA is widely used, yet the conventional equations used to compute PCSA were developed from two-dimensional (2D) interpretations of muscle architecture and may not…
Cassandra Kramer, Emily J. Reedich, Hope McCann, Sadie Drouin + 13 more
The distribution of slow-and fast-twitch fiber types in a skeletal muscle heavily influences its physiology. Muscle biopsy studies indicate atypical fiber type composition and fiber size variation in children with cerebral palsy (CP), but subjects have variable treatment history and a variety of muscles affected, so…
Leander A. Vonk, Osman Esen, Daan Hoomoedt, Rajvi M.N. Balesar + 2 more
Ex vivo culture of isolated muscle fibers can serve as an important model for in vitro research on mature skeletal muscle fibers. Nevertheless, this model has limitations for long-term studies due to structural loss and dedifferentiation following prolonged culture periods. This study aimed to investigate how ex vivo…
Karan Taneja, Xiaolong He, John A. Hodgson, Usha Sinha + 2 more
'Shantanu Sinha' 'J S Chen'] Experimental observations suggest that the force output of the skeletal muscle tissue can be correlated to the intra-muscular pressure generated by the muscle belly. However, pressure often proves difficult to measure through in-vivo tests. Simulations on the other hand, offer a tool to…
Kathryn N. Seow, Chun Y. Seow
Muscles convert chemical energy to mechanical work. Mechanical performance of a muscle is often assessed by the muscle’s ability to shorten and generate power over a range of loads or forces, characterized by the force-velocity and force-power relationships. The hyperbolic force-velocity relationship of muscle, for a…
Xenia V. Sergeeva, Irina D. Lvova, Kristina A. Sharlo, Andrea Telek
Skeletal muscle unloading occurs during a wide range of conditions, from space flight to bed rest. The unloaded muscle undergoes negative functional changes, which include increased fatigue. The mechanisms of unloading-induced fatigue are far from complete understanding and cannot be explained by muscle atrophy only.…
Authors not listed
Tissue engineering and regenerative medicine applications require the integration of multifunctional materials, offering appropriate mechanical cues and geometric guidance to support tissue-specific cell differentiation. In this context, supramolecular gel noodles formed by ionic cross-linking of pre-assembled micellar…
Aude Loumeaud, Philippe Pouletaut, Sabine F. Bensamoun, Daniel George + 1 more
'Daniel George' 'Simon Chatelin'] Abstract. Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some of these properties is currently not…