24 papers · ranked by Valyu relevance
James S. Dhaliwal, Cristina Panozzo, Lionel Benard, William Zerges
Cytoplasmic RNA granules compartmentalize phases of the translation cycle. We previously reported on the localization of oxidized RNA in human cells to cytoplasmic foci called oxidized RNA bodies (ORBs). Oxidized mRNAs are substrates of translation quality control, wherein defective mRNAs and nascent polypeptides are…
Junnan Fang, Dorothy A. Lerit
As the microtubule-organizing centers (MTOCs) of most cells, centrosomes engineer the bipolar mitotic spindle required for error-free mitosis. Drosophila Pericentrin (PCNT)-like protein (PLP) is a key centrosome component that directs formation of a pericentriolar material (PCM) scaffold required for PCM organization…
Marco, Liang Liang, Michael T. Goodrich, Shuang Zhao
A debate in the scientific literature has arisen regarding whether the orb depicted in Salvator Mundi, which has been attributed by some experts to Leonardo da Vinci, was rendered in a optically faithful manner or not. Some hypothesize that it was solid crystal while others hypothesize that it was hollow, with…
Isabelle Busseau, Stéphanie Pierson, Dany Séverac, Christelle Dantec + 1 more
Drosophila Orb, the homologue of vertebrate CPEB is a key translational regulator involved in oocyte polarity and maturation through poly(A) tail elongation of specific mRNAs. orb has also an essential function during early oogenesis which has not been addressed at the molecular level. Here, we show that orb prevents…
Mariya Zhukova, Konstantin V. Yakovlev, Justinn Barr, Rudolf A. Gilmutdinov + 3 more
Orb is one of two Drosophila mRNA-binding CPEB proteins that activate or repress translation by mediating polyadenylation and deadenylation of target mRNAs through interaction with CPE motifs in their 3’UTRs. Orb is one of the key regulators of oocyte specification and polarity. This regulation acts through…
Kazuki Hattori, Hiromi Kirisako, Megumi Matsuo, Sadao Ota
Intestinal organoids are powerful in vitro models, but their use in large-scale analyses remains constrained by the low throughput, labor-intensive handling, and high reagent consumption of conventional Matrigel dome culture. Here, we present Organoid-in-Bead (OrB), a vortex-based compartmentalization workflow that…
Jarosław Szumega, Lamine Bougueroua, Blerina Gkotse, Pierre Jouvelot + 1 more
'Federico Ravotti'] With the Open Science approach becoming important for research, the evolution towards open scientific-paper reviews is making an impact on the scientific community. However, there is a lack of publicly available resources for conducting research activities related to this subject, as only a limited…
Mei Yang, Hailing Yang, Lang Shen, Tonghui Xu
The orbitofrontal cortex (ORB) exhibits a complex structure and diverse functional roles, including emotion regulation, decision-making, and reward processing. Structurally, it comprises three distinct regions: the medial part (ORBm), the ventrolateral part (ORBvl), and the lateral part (ORBl), each with unique…
Christopher J. Derrick, Timothy T. Weil
Localised mRNA translation is a widespread mechanism for targeting protein synthesis, important for cell fate, motility and pathogenesis. In Drosophila, the spatiotemporal control of gurken/TGF-α mRNA translation is required for establishing the embryonic body axes. A number of recent studies have highlighted key…
Muhammad Hassen, Rudi Brits, Francois Schulz
For a semisimple unital Banach algebra A over C, and elements a, b ∈ A, we show that the similarity orbits, orb(a) and orb(b), over the principal component of the invertible group of A commute precisely when there is at least one nonzero complex number not belonging to the spectrum of any product a ′ b ′—where (a ′ …
Alessandra Gaia Saracini, Leonhard Held
Perspective Authors: ['Alessandra Gaia Saracini' 'Leonhard Held'] Outcome Reporting Bias (ORB) poses significant threats to the validity of meta-analytic findings. It occurs when researchers selectively report outcomes based on the significance or direction of results, potentially leading to distorted treatment effect…
Hoo Keat Wong, Ian D. Stephen, David R. T. Keeble
The own-race bias (ORB) is a reliable phenomenon across cultural and racial groups where unfamiliar faces from other races are usually remembered more poorly than own-race faces ([48]). By adopting a yes-no recognition paradigm, we found that ORB was pronounced across race groups (Malaysian-Malay, Malaysian-Chinese…
G. Modestino
The trajectory and the orbital velocity are determined for an object moving in a gravitational system, in terms of fundamental and independent variables. In particular, considering a path on equipotential line, the elliptical orbit is naturally traced, verifying evidently the keplerian laws. The case of the planets of…
Alexander Muacevic, John R Adler, Faizullah Mashriqi, Joe Iwanaga + 3 more
'Marios Loukas' "Anthony V D'Antoni" 'R. Shane Tubbs'] Penetrating injuries to the orbit represent a small but very complicated portion of head injuries. Because of the close proximity to many vital structures, any penetrating orbital injury requires a multidisciplinary follow-up. Cases of penetrating injuries have…
Mahender K Narula, Vikas Chaudhary, Dhiraj Baruah, Manoj Kathuria + 1 more
'Rama Anand'] Tuberculosis of the orbit is rare, even in places where tuberculosis is endemic. The disease may involve soft tissue, the lacrimal gland, or the periosteum or bones of the orbital wall. Intracranial extension, in the form of extradural abscess, and infratemporal fossa extension has been described. This…
Kumudini Sharma, Vikas Kanaujia, Anu Jain, Sukhdeep Bains + 1 more
'Suvarna Suman'] Purpose To report an unusual presentation of tuberculosis. Case Report A six-year old boy presented with left upper lid swelling of 15 days’ duration and an asymptomatic midline neck mass from 2 months ago. Imaging studies, and microbiologic tests which demonstrated acid-fast bacilli in the fine needle…
Alperen Vural, Andrea Luigi Camillo Carobbio, Marco Ferrari, Vittorio Rampinelli + 11 more
'Vittorio Rampinelli' 'Alberto Schreiber' 'Davide Mattavelli' 'Francesco Doglietto' 'Barbara Buffoli' 'Luigi Fabrizio Rodella' 'Stefano Taboni' 'Michele Tomasoni' 'Tommaso Gualtieri' 'Alberto Deganello' 'Lena Hirtler' 'Piero Nicolai'] Transorbital endoscopic approaches are increasing in popularity as they provide…
Yoshiharu Mukouyama, Kenya Tanaka, Shuji Nakanishi, Yoshihiro Nakato
The present work reveals that a prebiotic chemical system can generate self-organizing ability that leads to highly ordered structures and an active character such as free independent harmonious behavior. This result is the properties of natural things that have long been overlooked since Darwin’s theory of evolution…
Yoshiharu Mukouyama, Kenya Tanaka, Shuji Nakanishi, Yoshihiro Nakato
The emergence of life on Earth has attracted intense attention but remains unclear. A key problem is that the question of how living organisms can exhibit self-organizing ability that leads to highly ordered structures and active free independent behavior remains unanswered. This work reveals, by computer simulation…
Yoshiharu Mukouyama, Kenya Tanaka, Shuji Nakanishi, Yoshihiro Nakato
The emergence of life on Earth has attracted intense attention but remains unclear. A key problem is that the question of how living organisms can exhibit self-organizing ability that leads to highly ordered structures and active free independent behavior remains unanswered. This work reveals, by computer simulation…
Hideaki Kawakami, Kiyofumi Mochizuki, Hideko Goto, Naoki Watanabe + 1 more
'Takuji Tanaka'] Purpose. To report our findings in a case of orbital T-cell lymphoma in which all of the extraocular muscles (EOMs) were bilaterally and discretely enlarged and the patient had a moon face countenance. Case. A 59-year-old woman presented with visual disturbances in her left eye, hyperemia in both eyes…
Authors not listed
The twin property of aromaticity and antiaromaticity is one of the most important and well-known concepts in chemical structure and bonding, but it is also an over-a-century enigma as the necessary and sufficient conditions of aromaticity and antiaromaticity have not been fully understood yet, and the relationships…
Authors not listed
Lipid nanoparticle RNA (LNP-RNA) formulations are used for the delivery of vaccines and other therapies. RNA molecules are encapsulated within their interior through electrostatic interactions with positively charged lipids. The identity of the lipids that present at their surface play a role in how they interact with…
Amanda A. Sickafoose, A. S. Bosh, S. E. Levine, C. A. Zuluaga + 4 more
'Anja Genade' 'Karsten Schindler' 'Tim Lister' 'Michael J. Person'] Abstract: A stellar occultation by the large trans-Neptunian object (90482) Orcus was predicted to occur on 2017 March 07. Observations were made at five sites in North and South America: the 0.6-m Astronomical Telescope of the University of Stuttgart…