20 papers · ranked by Valyu relevance
P. Balasubramanian, N. E. Mastorakis, Mohammad Maktoomi
Electronic circuits and systems employed in mission- and safety-critical applications such as space, aerospace, nuclear plants etc. tend to suffer from multiple faults due to radiation and other harsh external phenomena. To overcome single or multiple faults from affecting electronic circuits and systems, progressive…
Catherine A. Spilling, Franklyn A. Howe, Thomas R. Barrick
1## INTRODUCTION Diffusion-weighted magnetic resonance imaging (dMRI) is sensitive to the effects of random translational motion of water molecules at the length scale of cellular and subcellular structures, allowing interrogation of healthy and pathological tissue properties beyond nominal image resolution.…
P. Balasubramanian, D. L. Maskell, N. E. Mastorakis, Talib Al-Ameri
Multiplication is a widely used arithmetic operation that is frequently encountered in micro-processing and digital signal processing. Multiplication is implemented using a multiplier, and recently, QDI asynchronous array multipliers were presented in the literature utilizing delay-insensitive double-rail data encoding…
P. Balasubramanian, Douglas L. Maskell, Nikos E. Mastorakis
—Mission-critical and safety-critical applications generally tend to incorporate triple modular redundancy (TMR) to embed fault tolerance in their physical implementations. In a TMR realization, an original function block, which may be a circuit or a system, and two exact copies of the function block are used to…
P Balasubramanian
In this technical note, we provide a comparison of the design metrics of various quasidelay-insensitive (QDI) asynchronous adders, where the adders correspond to diverse architectures. QDI adders are robust, and the objective of this technical note is to point to those QDI adders which are suitable for low power/energy…
P. Balasubramanian, Douglas L. Maskell, Nikos E. Mastorakis
We present a new asynchronous quasi-delay-insensitive (QDI) block carry lookahead adder with redundancy carry (BCLARC) realized using delay-insensitive dual-rail data encoding and 4-phase return-to-zero (RTZ) and 4-phase return-to-one (RTO) handshaking. The proposed QDI BCLARC is found to be faster and energy-efficient…
Thomas R. Barrick, Carson Ingo, Matt G. Hall, Franklyn A. Howe
'Franklyn\xa0A. Howe'] Title: ABSTRACT We demonstrate that quasi-diffusion imaging (QDI) is a signal representation that extends towards the negative power law regime. We evaluate QDI for in vivo human and ex vivo fixed rat brain tissue across -value ranges from 0 to 25,000 s mm−2, determine whether accurate parameter…
P. Balasubramanian, D. L. Maskell, N. E. Mastorakis, Jun Ma
We present a new asynchronous quasi-delay-insensitive (QDI) block carry lookahead adder with redundant carry (BCLARC) realized using delay-insensitive dual-rail data encoding and 4-phase return-to-zero (RTZ) and 4-phase return-to-one (RTO) handshaking. The proposed QDI BCLARC is found to be faster and energy-efficient…
Wei Zhang, Tim van Leent, Kai Redeker, Robert Garthoff + 6 more
users Authors: ['Wei Zhang' 'Tim van Leent' 'Kai Redeker' 'Robert Garthoff' 'René Schwonnek' 'Florian Fertig' 'Sebastian Eppelt' 'Valerio Scarani' 'Charles Ci Wen Lim' 'Harald Weinfurter'] Device-independent quantum key distribution (DIQKD) is the art of using untrusted devices to establish secret keys over an…
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Predicting molecular dipole moments is essential for quantum chemistry and materials science applications. In this study, we introduce Q-DFTNet: a Chemistry-Informed Neural Network framework designed to systematically benchmark and interpret graph neural networks (GNNs) for molecular dipole prediction. Seven GNN…
Soorya Pradeep, Thomas A. Zangle
Transport of mass within cells helps maintain homeostasis and is disrupted by disease and stress. Here, we develop quantitative phase velocimetry (QPV) as a label-free approach to make the invisible flow of mass within cells visible and quantifiable. We benchmark our approach against alternative image registration…
Di Ran, Yongguo Zhang, Yueqing An, Ying Hu + 2 more
Transfer RNA (tRNA) modifications determine translation fidelity and efficiency. It occurs through the action of specific enzymes that modify the nucleotides within the tRNA molecule. Our previous study demonstrated tRNA modopathies and altered queuine-related metabolites in inflammatory bowel diseases. Queuine…
Elizaveta I. Shestoperova, Daniil G. Ivanov, Eric R. Strieter
The diversity of ubiquitin modifications calls for methods to better characterize ubiquitin chain linkage, length, and morphology. Here, we use multiple linear regression analysis coupled with ion mobility mass spectrometry (IM-MS) to quantify the relative abundance of different ubiquitin dimer isomers. We demonstrate…
Jingfang Hao, Alexander Johansson, Johan Svensson Fall, Jianli Duan + 6 more
Photosynthetic organisms must balance light absorption and energy dissipation to prevent photo-oxidative damage. Non-photochemical quenching (NPQ) dissipates excess light energy as heat, with the quenching component qH providing sustained photoprotection. However, the molecular mechanism underlying qH induction remains…
Murilo Hoias Teixeira, Guilherme Menegon Arantes
Natural quinones are amphiphilic molecules that function as mobile charge carriers in biological energy transduction. Their distribution and permeation across membranes are important for binding to enzymatic complexes and for proton translocation. Here, we employ molecular dynamics simulations and free energy…
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Computational chemistry has entered a new era where machine learning (ML) models—particularly graph neural networks and machine learning force fields—routinely deliver quantum mechanical accuracy at classical speeds, scaling to millions of atoms and reshaping workflows in drug discovery, catalysis, and materials…
Benjamin Neely, Yasset Perez-Riverol, Magnus Palmblad
The past decade has seen widespread advances in quality control (QC) materials and software tools focused specifically on mass spectrometry-based proteomics, yet the rate of adoption is inconsistent. Despite the fundamental importance of QC, it typically falls behind learning new techniques, instruments, or software.…
Santiago Vargas, Winston Gee, Anastassia Alexandrova
We present a package, Generator, for geometric molecular property prediction based on topological features of quantum mechanical electron density. Generator computes Quantum Theory of Atoms in Molecules (QTAIM) features, at density functional theory (DFT) level, for sets of molecules or reac- tions in a high-throughput…
Zezhong Ye, Sam E. Gary, Peng Sun, Sourajit Mitra Mustafi + 9 more
Diffusion tensor imaging (DTI) has been employed for over two decades to noninvasively quantify central nervous system (CNS) diseases/injuries. However, DTI is an inadequate simplification of diffusion modeling in the presence of co-existing inflammation, edema, and crossing nerve fibers. We employed a tissue phantom…
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One of the main applications for which quantum computers are hoped to find utility is in simulating ground state energies and other observables of molecular chemical systems. The recently proposed sample-based diagonalization method is a readily implementable method for this task on current-day hardware using short…