28 papers · ranked by Valyu relevance
Stephen L. France
Review and Empirical Reanalysis Authors: ['Stephen L. France'] This article gives an integrative review of research using projective methods in the consumer research domain. We give a general historical overview of the use of projective methods, both in psychology and in consumer research applications, and discuss the…
Patrik Aspers, Ugo Corte
What is qualitative research? If we look for a precise definition of qualitative research, and specifically for one that addresses its distinctive feature of being “qualitative,” the literature is meager. In this article we systematically search, identify and analyze a sample of 89 sources using or attempting to define…
Jana Uher
Rating scales are popular methods for generating quantitative data directly by persons rather than automated technologies. But scholars increasingly challenge their foundations. This article contributes epistemological and methodological analyses of the processes involved in person-generated quantification. They are…
Malcolm Williams, Luke Sloan, Sin Yi Cheung, Carole Sutton + 2 more
'Sebastian Stevens' 'Libby Runham'] This paper reports on a quasi-experiment in which quantitative methods (QM) are embedded within a substantive sociology module. Through measuring student attitudes before and after the intervention alongside control group comparisons, we illustrate the impact that embedding has on…
Guido Thömmes, Martin Oliver Sailer, Nicolas Bonnet, Alex Carlton + 2 more
'Juan J. Abellán' 'Véronique Robert'] The pharmaceutical industry has experienced increasing costs and sustained high attrition rates in drug development over the last years. One proposal that addresses this challenge from a statistical perspective is the use of quantitative decision-making (QDM) methods to support a…
Mingze Bai, Jingwen Deng, Chengxin Dai, Julianus Pfeuffer + 1 more
Testing for significant differences in quantities on protein level is a common goal of many LFQ-based mass spectrometry proteomics experiments. Starting from a table of protein and/or peptide quantities from a fixed proteomics quantification software, there exists a multitude of tools and R packages to perform the…
Louis J. Gross, Rachel Patton McCord, Sondra LoRe, Vitaly V. Ganusov + 5 more
Substantial guidance is available on undergraduate quantitative training for biologists, including reports focused on biomedical science, but far less attention has been paid to the graduate curriculum. In this setting, we propose an innovative approach to quantitative education that goes beyond recommendations of a…
C. Wild
"An unexamined life is not worth living," said Socrates as his own life drew to a tragic close. Even more emphatically, an unexamined education is not worth delivering. Periodically, we need to examine what we are doing and why — starting from the most fundamental of fundamentals. Ograjenšek and Gal (2015, hereafter…
Stephanie C. Hicks, Rafael A. Irizarry
Normalization and preprocessing are essential steps for the analysis of high-throughput data including next-generation sequencing and microarrays. Multi-sample global normalization methods, such as quantile normalization, have been successfully used to remove technical variation from noisy data. These methods rely on…
Ntsandeni Moseya, Solomon Mashegoane, Saraswathie Govender, Malose Makhubela
Participants were presented with a Q-pack containing the main materials of the study: randomly numbered cards with individually printed statements (Q-set); a quasi-normal distribution grid (i.e. a grid typically used to rank-order statements along a continuum ranging between two extremes; see [F0001] for a post-sorting…
Fabjola Bilo, Paola Cirelli, Laura Borgese
This review explores X-ray fluorescence (XRF) for elemental analysis of particulate matter (PM) for air quality monitoring. The introduction presents PM classification based on size and composition, covering various elemental analysis methods while highlighting the increasing interest in XRF due to its non-destructive…
Leigh Goodson, Matt Vassar
Research in healthcare settings and medical education has relied heavily on quantitative methods. However, there are research questions within these academic domains that may be more adequately addressed by qualitative inquiry. While there are many qualitative approaches, ethnography is one method that allows the…
Wenqisi Pan, Zeyu Lu, Wei Jiang, Johan Lim + 2 more
In meta-analyses of continuous outcomes, the sample mean and standard deviation (SD) are essential for synthesizing effect sizes across studies. However, clinical studies frequently report alternative summary statistics, such as the median, quartiles, and range. To enable inclusion of such studies, various methods have…
Taylor Bolt, Jason S. Nomi, Danilo Bzdok, Lucina Q. Uddin
Methods for data analysis in the biomedical, life and social sciences are developing at a rapid pace. At the same time, there is increasing concern that education in quantitative methods is failing to adequately prepare students for contemporary research. These trends have led to calls for educational reform to…
Joseph Feldman, Daniel R. Kowal
Quantile regression is a powerful tool in epidemiological studies where interest lies in inferring how different exposures affect specific percentiles of the distribution of a health or life outcome. Existing methods either estimate conditional quantiles separately for each quantile of interest or estimate the entire…
Tullia Padellini, Håvard Rue
Quantile regression relates the quantile of the response to a linear predictor. For a discrete response distributions, like the Poission, Binomial and the negative Binomial, this approach is not feasible as the quantile function is not bijective. We argue to use a continuous model-aware interpolation of the quantile…
Mira Flasch, Gunda Koellensperger, Benedikt Warth
The chemical exposome consists of environmental exposures experienced throughout a lifetime but to date analytical approaches to investigate the plethora of low-abundance chemicals remain very limited. Liquid chromatography high-resolution mass spectrometry (HRMS) is commonly applied in untargeted exposome-wide…
Authors not listed
We develop a comprehensive theoretical framework for quantum-enhanced risk modeling in financial systems, establishing mathematical foundations for representing and computing risk factors using quantum states and operations. The theory begins by formulating portfolio risk as quantum observables, where correlations…
Elisabeth A Stelson, Roxanne Dupuis
Qualitative research methods are frequently described as “compatible” with quantitative epidemiologic methods. Instead of simply “compatible,” we argue that qualitative methods are epidemiologic methods. Especially in social epidemiology, which embraces the relationships between psychosocial, historical, contextual…
Bruno Falissard, Anne Révah, Suzanne Yang, Anne Fagot-Largeault
In recent decades, there has been widespread debate in the human and social sciences regarding the compatibility and the relative merits of quantitative and qualitative approaches in research. In psychiatry, depending on disciplines and traditions, objects of study can be represented either in words or using two types…
James Wellnitz, Sankalp Jain, Joshua Hochuli, Travis Maxfield + 3 more
Traditional best practices for Quantitative Structure Activity Relationship (QSAR) modeling recommend dataset balancing and balanced accuracy (BA) as the key desired objective of model development. This study challenges the conventional norms by recommending the use of models with the highest positive predictive value…
Martin Robinson, Alan Bond, Alexandr Simonov, Jie Zhang + 1 more
Recently, we have introduced the use of techniques drawn from Bayesian statistics to recover kinetic and thermodynamic parameters from voltammetric data, and were able to show that the technique of large amplitude ac voltammetry yielded significantly more accurate parameter values than the equivalent dc approach. In…
Authors not listed
The Single-probe is a multifunctional device that can be coupled to mass spectrometry (MS) for molecular analysis of microscale samples, such as single cells, tissue slices, and multicellular spheroids, under ambient conditions. In Single-probe single cell MS (SCMS) studies, this technique leverages direct sampling and…
Haim Bar, James G. Booth, Martin T. Wells
It is known that the estimating equations for quantile regression (QR) can be solved using an EM algorithm in which the M-step is computed via weighted least squares, with weights computed at the E-step as the expectation of independent generalized inverse-Gaussian variables. This fact is exploited here to extend QR to…
Shuangyang Dai, Hong Xu, Beibei Li, Jingao Zhang + 1 more
Observational studies plays an important role in urology studies, But few studies have paid attention to the statistical reporting quality of observational studies. The purpose of this study was to investigate the frequency and evaluate the reporting quality of statistical methods of the published observational studies…
José Fausto de Morais, Gecilmar Pereira Borges, Gilmar Fernandes do Prado
The statistical analysis is an important part of the process of assessing the quality of randomized controlled trials, unfortunately it tends to be underestimated or even omitted by editors, in this sense, scales that cover this gap becomes necessary. To build a definition and a scale for assessing the quality of…
Berna Devezer, Danielle J. Navarro, Joachim Vandekerckhove, Erkan Ozge Buzbas
Current attempts at methodological reform in sciences come in response to an overall lack of rigor in methodological and scientific practices in experimental sciences. However, some of these reform attempts suffer from the same mistakes and over-generalizations they purport to address. Considering the costs of allowing…
Amelia Carolina Sparavigna
Previous studies (Sparavigna, 2023) have demonstrated the Tsallis q-Gaussian functions suitable for the analysis of Raman spectra. Here we consider two asymmetric forms of them, with the aim of further improving the fitting of Raman spectra. The first asymmetric form, that we are here proposing for the first time, is a…