9 papers · ranked by Valyu relevance
Christina Ludwig, Ludovic Gillet, George Rosenberger, Sabine Amon + 2 more
'Ben C Collins' 'Ruedi Aebersold'] Title: Abstract Many research questions in fields such as personalized medicine, drug screens or systems biology depend on obtaining consistent and quantitatively accurate proteomics data from many samples. SWATH-MS is a specific variant of data-independent acquisition (DIA) methods…
Chuan-Qi Zhong, Jianfeng Wu, Xingfeng Qiu, Xi Chen + 2 more
'Jiahuai Han'] Targeted SWATH-MS data analysis is critically dependent on the spectral library. Comprehensive spectral libraries of human or several other organisms have been published, but the extensive spectral library for mouse, a widely used model organism is not available. Here, we present a large murine spectral…
Peter Blattmann, Moritz Heusel, Ruedi Aebersold, Lennart Martens
SWATH-MS is an acquisition and analysis technique of targeted proteomics that enables measuring several thousand proteins with high reproducibility and accuracy across many samples. OpenSWATH is popular open-source software for peptide identification and quantification from SWATH-MS data. For downstream statistical and…
Lukas Krasny, Philip Bland, Jessica Burns, Nadia Carvalho Lima + 13 more
'Peter T. Harrison' 'Laura Pacini' 'Mark L. Elms' 'Jian Ning' 'Victor Garcia Martinez' 'Yi-Ru Yu' 'Sophie E. Acton' 'Ping-Chih Ho' 'Fernando Calvo' 'Amanda Swain' 'Beatrice A. Howard' 'Rachael C. Natrajan' 'Paul H. Huang'] Title: ABSTRACT SWATH-mass spectrometry (MS) enables accurate and reproducible proteomic…
Pawel Palmowski, Rachael Watson, G. Nicholas Europe‐Finner, Magdalena Karolczak‐Bayatti + 3 more
'Magdalena Karolczak‐Bayatti' 'Andrew Porter' 'Achim Treumann' 'Michael J. Taggart'] Title: Abstract Advances in liquid chromatography-mass spectrometry have facilitated the incorporation of proteomic studies to many biology experimental workflows. Data-independent acquisition platforms, such as sequential window…
Ziyue Wang, Michael Mülleder, Ihor Batruch, Anjali Chelur + 10 more
The possibility to record proteomes in high throughput and at high quality has opened new avenues for biomedical research, drug discovery, systems biology, and clinical translation. However, high-throughput proteomic experiments often require high sample amounts and can be less sensitive compared to conventional…
Jianbo Fu, Jing Tang, Yunxia Wang, Xuejiao Cui + 7 more
'Jiajun Hong' 'Xiaoxu Li' 'Shuang Li' 'Yuzong Chen' 'Weiwei Xue' 'Feng Zhu'] Sequential windowed acquisition of all theoretical fragment ion mass spectra (SWATH-MS) has emerged as one of the most popular techniques for label-free proteome quantification in current pharmacoproteomic research. It provides more…
Xiangfang Tang, Qingshi Meng, Jie Gao, Sheng Zhang + 2 more
'Minhong Zhang'] High temperature is one of the key environmental stressors affecting broiler production efficiency and meat yield. Knowledge of broiler self-regulation mechanisms under heat stress is important for the modern scale of poultry breeding. In the present study, the SWATH strategy was employed to…
Corinna Schultheiss, Thomas Schauer, Holger Nahrstaedt, Rainer O. Seidl
'Rainer O. Seidl'] Introduction. Developing an automated diagnostic and therapeutic instrument for treating swallowing disorders requires procedures able to reliably detect and evaluate a swallow. We tested a two-stage detection procedure based on a combined electromyography/bioimpedance (EMBI) measurement system. EMBI…