19 papers · ranked by Valyu relevance
Koen Van den Berge, Charlotte Soneson, Mark D. Robinson, Lieven Clement
'Lieven Clement'] RNA sequencing studies with complex designs and transcript-resolution analyses involve multiple hypotheses per gene; however, conventional approaches fail to control the false discovery rate (FDR) at gene level. We propose stageR, a two-stage testing paradigm that leverages the increased power of…
Koen Van den Berge, Charlotte Soneson, Mark D. Robinson, Lieven Clement
Reductions in sequencing cost and innovations in expression quantification have prompted an emergence of RNA-seq studies with complex designs and data analysis at transcript resolution. These applications involve multiple hypotheses per gene, leading to challenging multiple testing problems. Conventional approaches…
Pranab Ghosh, Lingyun Liu, Cyrus Mehta
Two methods for designing adaptive multiarm multistage (MAMS) clinical trials, originating from conceptually different group sequential frameworks are presented, and their operating characteristics are compared. In both methods pairwise comparisons are made, stage-by-stage, between each treatment arm and a common…
Shiyang Ma, Michael P. McDermott
In learning-phase clinical trials in drug development, adaptive designs can be efficient and highly informative when used appropriately. In this article, we extend the multiple comparison procedures with modeling techniques (MCP-Mod) procedure with generalized multiple contrast tests (GMCTs) to two-stage adaptive…
Nerea Arandia, Jose Ignacio Garate, Jon Mabe, Mia Folke + 3 more
'Maria Linden' 'Mats Björkman' 'Ning Xiong'] Embedded systems have become a key technology for the evolution of medical devices. However, the regulatory requirements that must be met make designing and developing these devices challenging. As a result, many start-ups attempting to develop medical devices fail.…
Tara N. Furstenau, Jill H. Cocking, Crystal M. Hepp, Viacheslav Y. Fofanov
Due to the large number of negative tests, individually screening large populations for rare pathogens can be wasteful and expensive. Sample pooling methods improve the efficiency of large-scale pathogen screening campaigns by reducing the number of tests and reagents required to accurately categorize positive and…
Christian R Werner, Giovanny Covarrubias-Pazaran, David González-Diéguez, Dorcus C Gemenet + 2 more
Early-stage sparse testing can significantly increase genetic gain in plant breeding programmes, facilitating the development of varieties with high and stable performance across farmers’ fields. This is achieved through (1) increased selection accuracy, enabled by broader sampling of trial sites across the Target…
M. Hanefi Calp, Utku Köse
| Article Info | Abstract | | --- | --- | | Received: 05/03/2018 Accepted: 08/05/2018 | Software testing process consists of activities that implemented after it is planned and including | | | to document related testing activities. Test processes must be applied necessarily for able to | | | clearly see the quality of…
Jimi Sanchez
Pair-wise testing is a type of combinatorial software testing, used in test case generation. Pair-wise testing helps prune the combinatorial explosion that can occur when attempting to test a system with many input options. Pair-wise testing often yields good results at a low cost. However, Pair-wise testing may miss…
T. R. Gopalakrishnan Nair, V. Suma, Pranesh Kumar Tiwari
— One of the prerequisites of any organization is an unvarying sustainability in the dynamic and competitive industrial environment. Development of high quality software is therefore an inevitable constraint of any software industry. Defect management being one of the highly influencing factors for the production of…
David Brust, Johannes J. Brust
Grouping samples with low prevalence of positives into pools and testing these pools can achieve considerable savings in testing resources compared with individual testing in the context of COVID-19. We review published pooling matrices, which encode the assignment of samples into pools and describe decoding…
Yuta Tokuoka, Tsutomu Endo, Takashi Morikura, Yuki Hiradate + 2 more
Infertility is a global issue, with approximately 50% of cases attributed to defective spermatogenesis. For studies into spermatogenesis and spermatogenic dysfunction, evaluating the seminiferous tubule stage is essential. However, the current method of evaluation involves labor-intensive and time-consuming manual…
Maria Jose Fuster-RuizdeApodaca, Ana Laguia, Fernando Molero, Javier Toledo + 2 more
'Javier Toledo' 'Arantxa Arrillaga' 'Angeles Jaen'] Background The goal of this research is to study the psychosocial determinants of HIV-testing as a function of the decision or change stage concerning this health behavior. The determinants considered in the major ongoing health models and the stages contemplated in…
Fuzhan Rahmanian, Robert M. Lee, Dominik Linzner, Kathrin Michel + 4 more
Predicting and monitoring battery life early and across chemistries is a significant challenge due to the plethora of degradation paths, form factors, and electrochemical testing protocols. Existing models typically translate poorly across different electrode, electrolyte, and additive materials, mostly require a fixed…
Johan H. Cronje, Mark B. Watson, Louise-Anne Stroud, Maciej Karwowski
'Maciej Karwowski'] Tests are updated and revised periodically in order to remain current, valid and reliable in a competitive psychological testing industry. Despite the prevalence of test revisions, especially in recent years, a number of authors have commented on the lack of comprehensive guidelines for test…
Eitan Farchi, Debbie Furman
| 1 | | Introduction | 1 | | --- | --- | --- | --- | | 2 | | A roller coaster introduction to Combinatorial Test Design | 2 | | | 2.1 | Introduction | 2 | | | 2.2 | Variables definition | 3 | | | | 2.2.1 Decide which variables are part of the model and which should be randomized | 3 | | | | 2.2.2 Sub-domain partition…
Durga Shree Nagabushanam, Sree Dharinya S, V. Sree Dharinya, Nadendla Sai Roopa + 1 more
'Nadendla Sai Roopa' 'Anugu Arun'] Abstract— The requirements in automation, digitalization, and fast computations have loaded the IT sector with expectations of highly reliable, efficient, and cost-effective software. Given that the process of testing, verification, and validation of software products consumes 50-75%…
Haley Hunter-Zinck, Alexandre Fioravante de Siqueira, Váleri N. Vásquez, Richard Barnes + 2 more
'Váleri N. Vásquez' 'Richard Barnes' 'Ciera C. Martinez' 'Scott Markel'] Functional, usable, and maintainable open-source software is increasingly essential to scientific research, but there is a large variation in formal training for software development and maintainability. Here, we propose 10 “rules” centered on 2…
Authors not listed
Acoustic measurements of batteries are known to be correlated to their state-of-charge, creating opportunities for state estimation that do not rely on electrical signals. State estimators are typically parametric models fitted from data, often from the broad toolbox of machine learning. Such models can be easily…