18 papers · ranked by Valyu relevance
Natalya Zahn, Christina James-Zorn, Virgilio G. Ponferrada, Dany S. Adams + 7 more
'Dany S. Adams' 'Julia Grzymkowski' 'Daniel R. Buchholz' 'Nanette M. Nascone-Yoder' 'Marko Horb' 'Sally A. Moody' 'Peter D. Vize' 'Aaron M. Zorn'] Title: ABSTRACT Normal tables of development are essential for studies of embryogenesis, serving as an important resource for model organisms, including the frog Xenopus…
Laznovsky Jakub, Kavkova Michaela, Reis Alice, Robovska-Havelkova Pavla + 5 more
Xenopus laevis, the African clawed frog, is a versatile vertebrate model organism employed across various biological disciplines, prominently in developmental biology to elucidate the intricate processes underpinning body plan reorganization during metamorphosis. Despite its widespread utility, a notable gap exists in…
Kelly Miller, Clotilde Cadart, Rebecca Heald
Genome and cell size are strongly correlated across species^1–6^ and influence physiological traits like developmental rate^7–12^. Although size scaling features such as the nuclear-cytoplasmic (N/C) ratio are precisely maintained in adult tissues^13^, it is unclear when during embryonic development size scaling…
Laura Maria Mendes Campitelli, Karina Pereira Lopes, Isabela Lemos de Lima, Flávia Batista Ferreira + 12 more
'Isabela Lemos de Lima' 'Flávia Batista Ferreira' 'Nayara Delfim Isidoro' 'Giovana Magalhães Ferreira' 'Maria Clara Fioravanti Ponce' 'Milene Caroline de Oliveira Ferreira' 'Ludmilla Silva Mendes' 'Pedro Henrique Ribeiro Marcelino' 'Matheus Morais Neves' 'Sandra Gabriela Klein' 'Belchiolina Beatriz Fonseca' 'Richard…
Rosa Carotenuto, Maria Michela Pallotta, Margherita Tussellino, Chiara Fogliano + 1 more
Simple Summary Xenopus laevis is an anuran amphibian that has been used for decades as the principal vertebrate model to study embryonic development. Among the advantages of this species, one can mention its evolutionary closeness to higher vertebrates in terms of physiology, gene expression and organ development. In…
John N. Griffin, Karen J. Liu, Emily Sempou
We have long extrapolated from animal models to better understand our own biology and health. Amongst such models, amphibia, and in particular Xenopus, have emerged as a powerhouse of biological discovery, providing startling insights into fundamental processes in embryology, cell biology, genetics, physiology…
Patrick Narbonne, David E. Simpson, John B. Gurdon, Tom Misteli
Defects in induction signaling and response underlie the nucleocytoplasmic incompatibility between two evolutionarily distant frog species, while specific treatments partially restore this response in explants and whole embryos.
Mathieu Le Verge-Serandour, Hervé Turlier
| ABSTRACT | 2 | | --- | --- | | INTRODUCTION | 2 | | MECHANISMS FOR BLASTOCOEL MORPHOGENESIS | 5 | | SEA URCHIN: SURFACE PLANE DIVISIONS | 5 | | XENOPUS: OSMOTIC FLUID PUMPING | 5 | | MOUSE EMBRYO: HYDRAULIC FRACTURING AND COARSENING | 6 | | MARSUPIALS: SHELL ADHESION AND CELL PROLIFERATION | 6 | | A PHYSICS…
Xin Li, Robert J. Huebner, Margot Williams, Jessica K. Sawyer + 3 more
'Mark Peifer' 'John B. Wallingford' 'D. Thirumalai'] Cells undergo dramatic changes in morphology during embryogenesis, yet how these changes affect the formation of ordered tissues remains elusive. Here we find that the emergence of a nematic liquid crystal phase occurs in cells during gastrulation in the development…
Eric D. Siggia
Development from egg to embryo to adult is a fascinating instance of biological self-organization for which genetics has supplied us with a parts list. It remains to find the principles organizing the assembly of those parts. In the last decade embryonic stem cells (ESC) have provided the material from which to build…
Caroline W. Beck, Joanna Ward, Lisa Troise, Catherine Brochard
**The grem1 gene codes a protein that inhibits the action of multiple members of a growth factor family known as bone morphogenetic proteins (BMPs). Certain members of this BMP family can regulate both fecundity and fertility in mammals via their action on oocyte (egg) development, and grem1 has been identified as a…
Gary J. Gorbsky, John R. Daum, Hem Sapkota, Katja Summala + 5 more
The diploid anuran, Xenopus tropicalis, has emerged as a key research model in cell and developmental biology. To enhance the usefulness of this species, we developed methods for generating immortal cell lines from Nigerian strain (NXR_1018, RRID:SCR_013731) X. tropicalis embryos. We generated 14 cell lines that were…
Claudiu V. Giuraniuc, Shabana Zain, Shahmama Ghafoor, Stefan Hoppler
embryogenesis Authors: ['Claudiu V. Giuraniuc' 'Shabana Zain' 'Shahmama Ghafoor' 'Stefan Hoppler'] There are two phases of Wnt signalling in early vertebrate embryogenesis: very early, maternal Wnt signalling promotes dorsal development, and slightly later, zygotic Wnt signalling promotes ventral and lateral mesoderm…
Romain Gibeaux, Kelly Miller, Rachael Acker, Taejoon Kwon + 1 more
Determining how size is controlled is a fundamental question in biology that is poorly understood at the organismal, cellular and subcellular levels. The Xenopus species, X. laevis and X. tropicalis differ in size at all three of these levels. Despite these differences, fertilization of X. laevis eggs with X.…
Susan Schweiger, Benjamin Naumann, Hendrik Müller
Terrestrialization in anurans is associated with the evolution of endotrophy. It is hypothesized that heterochrony, or changes in the time or rate of developmental events, is associated with the development in endotrophic species. To analyse the developmental heterochrony, we investigated and revised the description of…
Kerim Anlaş, Vikas Trivedi
> The metazoan body plan is established during early embryogenesis via collective cell rearrangements and evolutionarily conserved gene networks, as part of a process commonly referred to as gastrulation. While substantial progress has been achieved in terms of characterizing the embryonic development of several model…
Andres Collazo, Ray Keller
Background Comparative analyses between amphibians, concentrating on the cellular mechanisms of morphogenesis, reveal a large variability in the early developmental processes that were thought to be conserved during evolution. Increased egg size is one factor that could have a strong effect on early developmental…
Sebastian Knitter, Changgeng Liu, Brandon Redding, Mustafa K. Khokha + 2 more
'Michael A. Choma' 'Hui Cao'] We demonstrate a VECSEL (vertical external cavity surface emitting laser) based degenerate source with an adjustable degree of spatial coherence that is electrically pumped, mechanically compact and supports continuous-wave emission. The laser operation can be switched between a large…