24 papers · ranked by Valyu relevance
Nicolai Simon, Thomas Stieglitz, Volker Bucher
Area-selective atomic layer deposition (ASD) is a bottom-up process that is of particular importance in the semiconductor industry, as it prevents edge defects and avoids cost-intensive lithography steps. This approach not only offers immense potential for the manufacture of active implants but can also be used to…
Inês Peres, Pedro Rolo, Marco P. Soares dos Santos
Implantable medical devices have been developed to provide multifunctional ability to numerous bioapplications. In the scope of orthopaedics, four methodologies were already proposed to design implant technologies: non-instrumented passive implants, non-instrumented active implants, instrumented passive implants and…
Alina Kohler, Felix Blendinger, Sonja Müller, Ulrich Mescheder + 1 more
'Volker Bucher'] Parylene C is well-known as an encapsulation material for medical implants. Within the approach of miniaturization and automatization of a bone distractor, piezoelectric actuators were encapsulated with Parylene C. The stretchability of the polymer was investigated with respect to the encapsulation…
Martin HJ Busch, Wolfgang Vollmann, Jörg Schnorr, Dietrich HW Grönemeyer
'Dietrich HW Grönemeyer'] Background Active Magnetic Resonance Imaging implants are constructed as resonators tuned to the Larmor frequency of a magnetic resonance system with a specific field strength. The resonating circuit may be embedded into or added to the normal metallic implant structure. The resonators build…
Theresa Reiter, Ingo Weiss, O. Weber, Wolfgang R. Bauer
All measurements were obtained at a clinical 3.0T scanner using an in-house designed cubic phantom and optimized sequences for artifact evaluation (3D gradient echo sequence, multi-slice 2D turbo spin echo sequence). Reference sequences according to the American Society for Testing and Materials (ASTM) were…
Piotr Wychowański, Anna Starzyńska, Paulina Adamska, Monika Słupecka-Ziemilska + 9 more
'Monika Słupecka-Ziemilska' 'Bartosz Kamil Sobocki' 'Agnieszka Chmielewska' 'Bartłomiej Wysocki' 'Daniela Alterio' 'Giulia Marvaso' 'Barbara Alicja Jereczek-Fossa' 'Jan Kowalski' 'Elena Maria Varoni' 'Piero Papi'] Dental implants are, nowadays, established surgical devices for the restoration of lost teeth. Considered…
Konlin Shen, Michel M. Maharbiz
The lifetime of neural implants is strongly dependent on packaging due to the aqueous and biochemically aggressive nature of the body. Over the last decade, there has been a drive towards neuromodulatory implants which are wireless and approaching millimeter-scales with increasing electrode count. A so-far unrealized…
Mihály Vöröslakos, Omid Yaghmazadeh, Leeor Alon, Daniel K. Sodickson + 1 more
Over the past few decades, daily exposure to radiofrequency (RF) fields has been increasing due to the rapid development of wireless and medical imaging technologies. Under extreme circumstances, exposure to very strong RF energy can lead to heating of body tissue, even resulting in tissue injury. The presence of…
Braeden Benedict, Mohammad Meraj Ghanbari, Rikky Muller
—Millimeter-scale implants using ultrasound for power and communication have been proposed for a range of deep-tissue applications, including neural recording and stimulation. However, published implementations have shown high sensitivity to misalignment with the external ultrasound transducer. Ultrasonic beamforming…
Annina Mittelholzer, Vincent Hickl, Katharina Maniura-Weber, Luciano F. Boesel + 3 more
Smart hydrogels are promising materials for soft actuators in biomedical applications thanks to their varied responses to external stimuli. Light is a particularly attractive trigger for contactless stimulation of hydrogels that can induce reversible morphological changes without damaging the fragile gels. To meet the…
Guy Fierens, Joris Walraevens, Ronald Peeters, Christ Glorieux + 1 more
'Nicolas Verhaert'] *Corresponding author: Guy Fierens, Laboratory for Soft Matter and Biophysics, Department for Physics and Astronomy, Celestijnenlaan 200D, Box 2416, 3000 Leuven. Email: guy.fierens@kuleuven.be Grant support: This work has been partly supported by Flanders Innovation and Entrepreneurship…
Gerardo Asensio, Blanca Vázquez-Lasa, Luis Rojo
Titanium and its alloys constitute the gold standard materials for oral implantology in which their performance is mainly conditioned by their osseointegration capacity in the host’s bone. We aim to provide an overview of the advances in surface modification of commercial dental implants analyzing and comparing the…
Jonathan T. Su, Solange M Simpson, Samuel Sung, Ewa Bryndza Tfaily + 13 more
We describe the in vitro and in vivo evaluation of a subcutaneous reservoir implant delivering tenofovir alafenamide hemifumarate (TAF) for the prevention of HIV infection. These long-acting reservoir implants were able to deliver antiretroviral drug for over 90 days in vitro and in vivo. We evaluated the implants for…
Aliya Sharipova, Olga Bakina, Aleksandr Lozhkomoev, Marat Lerner + 2 more
Biodegradable metals emerged as promising temporary bone implants. The integration of additional features such as local drug delivery (LDD) can also support their osteointegration, promote bone regeneration, and prevent biomaterial-centered infections that are difficult to treat. LDD is achieved by drug-eluting…
Thibault Couture, Jérôme Szewczyk
We first establish the specifications of our device considering anatomical constraints. We then present a new method for building active SMA-based catheters. The proposed method relies on the use of a core body made of three parallel metallic beams and integrates wire-shaped SMA actuators. The complete device is…
Authors not listed
Advancements in biomedical technologies increasingly demand biocompatible and biodegradable materials capable of integrating with the body for real-time monitoring of physiological processes. Aortic annuloplasty, a procedure to stabilize the aortic root and restore valve function in cases of regurgitation and root…
Gabriel Onyenso, Swathi Naidu Vakamulla Raghu, Patrick Hartwich, Manuela Killian
The integration of drug delivery coating in orthopedic applications is attracting interest due to its potential to improve the success rate of implant systems. Several published reports have focused on the aspect of controlled drug release to aid in the optimization of drug delivery. Herein, we report on a novel and…
Gabriel Onyenso, Jiwar AI-Zawity, Nastaran Farahbakhsh, Annika Schardt + 6 more
The outcome of an implant procedure largely depends on the implant's surface properties. Biomaterials are now required to have surfaces with multifunctionality such as favorable tissue integration and the ability to combat bacterial adhesion and colonization. Herein, we report on a simple approach to improving the…
Authors not listed
Dental implants have become the primary alternative for patients with lost teeth, but biofilm formation and subsequent bacterial-associated infections, like peri-implantitis, are persistent challenges. The development of antibacterial implant coatings is an important approach to reduce or prevent bacterial infections…
Irina Kondyurina, Alexey Kondyurin
Despite on great success with artificial implant for human body, the modern implants could not solve major health problems. The reason is an immune reaction of organism on artificial implant known as foreign body reaction. We have found a way to avoid or decrease the foreign body reaction. The surface of artificial…
Authors not listed
The development of metal-organic framework (MOF) crystal-glass composites (CGCs) has been hindered by the scarcity of MOF glass matrices with low glass transition temperatures (Tgs). Here, we investigate a CGC consisting of a low-Tg MOF glass, (agZIF-UC-7) and UiO-66. Powder X-ray diffraction and stability tests in…
Noor Abu Jarad, Jeffrey I Weitz, Tohid Didar
Improving the performance of blood-contacting medical implants is a global health necessity aimed at reducing mortality and morbidity in patients with cardiovascular diseases. Surface modification of the biomaterials from which the implants are constructed has been used to reduce the risk of complications such as…
Li Yue, Liu Geng
To delineate the evolutionary trajectory of immunomodulatory biomaterials in implant osseointegration through bibliometric analysis, identifying pivotal theoretical breakthroughs and technological advancements. A total of 419 articles (2005–2025) from the Web of Science Core Collection were analyzed using a multi-tool…
Ritambhara Dash, Abhay Kumar Rajak, Ramagiri Praveen Kumar, Parameshwar Kommu + 3 more
Bio ceramics have enormous applications in the medical field as being used as implants. The base material in bioceramics is mostly calcium phosphate which comes in the form of hydroxyapatite (HAp) or Beta-tricalcium phosphate (β-TCP). The other materials are silica and alumina. The different blends of these bioceramics…