22 papers · ranked by Valyu relevance
Nicolai Simon, Thomas Stieglitz, Volker Bucher
Area-selective atomic layer deposition (ASD) is a bottom-up process that is of particular importance in the semiconductor industry, as it prevents edge defects and avoids cost-intensive lithography steps. This approach not only offers immense potential for the manufacture of active implants but can also be used to…
Lukas Holzapfel, Vasiliki Giagka
Traditionally, active implants are powered by batteries, which, when discharged, have to be either replaced or recharged by an inductive power link. In the recent years, ultrasonic power links are also being investigated, as they promise more available power for deeply implanted miniaturized devices. Such devices often…
Inês Peres, Pedro Rolo, Marco P. Soares dos Santos
Implantable medical devices have been developed to provide multifunctional ability to numerous bioapplications. In the scope of orthopaedics, four methodologies were already proposed to design implant technologies: non-instrumented passive implants, non-instrumented active implants, instrumented passive implants and…
Alina Kohler, Felix Blendinger, Sonja Müller, Ulrich Mescheder + 1 more
'Volker Bucher'] Parylene C is well-known as an encapsulation material for medical implants. Within the approach of miniaturization and automatization of a bone distractor, piezoelectric actuators were encapsulated with Parylene C. The stretchability of the polymer was investigated with respect to the encapsulation…
Eduard Ferrés-Amat, Ashraf Al Madhoun, Elvira Ferrés-Amat, Saddam Al Demour + 8 more
'Saddam Al Demour' 'Mera A. Ababneh' 'Eduard Ferrés-Padró' 'Carles Marti' 'Neus Carrio' 'Miguel Barajas' 'Maher Atari' 'Gianmario Schierano' 'Giuliana Muzio'] Background: Bioactive chemical surface modifications improve the wettability and osseointegration properties of titanium implants in both animals and humans. The…
Panagiotis Kassanos, Emmanouel Hourdakis, Egidio De Benedetto
In recent years, implantable sensors have been extensively researched since they allow localized sensing at an area of interest (e.g., within the vicinity of a surgical site or other implant). They allow unobtrusive and potentially continuous sensing, enabling greater specificity, early warning capabilities, and thus…
Braeden Benedict, Mohammad Meraj Ghanbari, Rikky Muller
—Millimeter-scale implants using ultrasound for power and communication have been proposed for a range of deep-tissue applications, including neural recording and stimulation. However, published implementations have shown high sensitivity to misalignment with the external ultrasound transducer. Ultrasonic beamforming…
Mihály Vöröslakos, Omid Yaghmazadeh, Leeor Alon, Daniel K. Sodickson + 1 more
Over the past few decades, daily exposure to radiofrequency (RF) fields has been increasing due to the rapid development of wireless and medical imaging technologies. Under extreme circumstances, exposure to very strong RF energy can lead to heating of body tissue, even resulting in tissue injury. The presence of…
Wei Wang, Zhanghao Yu, Yiwei Zou, Joshua Woods + 4 more
'Yumin Su' 'Jacob T. Robinson' 'Kaiyuan Yang'] Abstract—Miniature bioelectronic implants promise revolutionary therapies for cardiovascular and neurological disorders. Wireless power transfer (WPT) is a significant method for miniaturization, eliminating the need for bulky batteries in today's devices. Despite…
Annina Mittelholzer, Vincent Hickl, Katharina Maniura-Weber, Luciano F. Boesel + 3 more
Smart hydrogels are promising materials for soft actuators in biomedical applications thanks to their varied responses to external stimuli. Light is a particularly attractive trigger for contactless stimulation of hydrogels that can induce reversible morphological changes without damaging the fragile gels. To meet the…
Guy Fierens, Joris Walraevens, Ronald Peeters, Christ Glorieux + 1 more
'Nicolas Verhaert'] *Corresponding author: Guy Fierens, Laboratory for Soft Matter and Biophysics, Department for Physics and Astronomy, Celestijnenlaan 200D, Box 2416, 3000 Leuven. Email: guy.fierens@kuleuven.be Grant support: This work has been partly supported by Flanders Innovation and Entrepreneurship…
Alexander J. Boys, Alejandro Carnicer Lombarte, Amparo Güemes Gonzalez, Douglas C. van Niekerk + 5 more
Bioelectronics hold the key for understanding and treating disease. However, achieving stable, long-term interfaces between electronics and the body remains a challenge. Implantation of a bioelectronic device typically initiates a foreign body response, which can limit long-term recording and stimulation efficacy.…
Biqi Rebekah Zhao, Alexander Chou, Robert Peltekov, Elad Alon + 3 more
-Magnetic resonance imaging (MRI) exhibits rich and clinically useful endogenous contrast mechanisms, which can differentiate soft tissues and are sensitive to flow, diffusion, magnetic susceptibility, blood oxygenation level, and more. However, MRI sensitivity is ultimately constrained by Nuclear Magnetic Resonance…
Aliya Sharipova, Olga Bakina, Aleksandr Lozhkomoev, Marat Lerner + 2 more
Biodegradable metals emerged as promising temporary bone implants. The integration of additional features such as local drug delivery (LDD) can also support their osteointegration, promote bone regeneration, and prevent biomaterial-centered infections that are difficult to treat. LDD is achieved by drug-eluting…
Raquel J. Ibáñez Alcalá, Andrea Y. Macias, Cory N. Heaton, Ricardo Sosa Jurado + 12 more
Electrophysiological implants enable exploration of the relationship between neuronal activity and behavior. These technologies evolve rapidly, with multiple iterations of recording systems developed and utilized. Chronic implants must address a litany of complications, including retention of high signal-to-noise ratio…
Aziliz Guezou‐Philippe, Arnaud Clavé, Ehouarn Maguet, Ludivine Maintier + 5 more
implants: application to total knee arthroplasty Authors: ['Aziliz Guezou‐Philippe' 'Arnaud Clavé' 'Ehouarn Maguet' 'Ludivine Maintier' 'Charles Garraud' 'Jean-Rassaire Fouefack' 'Valérie Burdin' 'Éric Stindel' 'Guillaume Dardenne'] Osteoarthritis affects about 528 million people worldwide, causing pain, swelling and…
Authors not listed
Advancements in biomedical technologies increasingly demand biocompatible and biodegradable materials capable of integrating with the body for real-time monitoring of physiological processes. Aortic annuloplasty, a procedure to stabilize the aortic root and restore valve function in cases of regurgitation and root…
Gabriel Onyenso, Swathi Naidu Vakamulla Raghu, Patrick Hartwich, Manuela Killian
The integration of drug delivery coating in orthopedic applications is attracting interest due to its potential to improve the success rate of implant systems. Several published reports have focused on the aspect of controlled drug release to aid in the optimization of drug delivery. Herein, we report on a novel and…
Gabriel Onyenso, Jiwar AI-Zawity, Nastaran Farahbakhsh, Annika Schardt + 6 more
The outcome of an implant procedure largely depends on the implant's surface properties. Biomaterials are now required to have surfaces with multifunctionality such as favorable tissue integration and the ability to combat bacterial adhesion and colonization. Herein, we report on a simple approach to improving the…
Authors not listed
Dental implants have become the primary alternative for patients with lost teeth, but biofilm formation and subsequent bacterial-associated infections, like peri-implantitis, are persistent challenges. The development of antibacterial implant coatings is an important approach to reduce or prevent bacterial infections…
Authors not listed
The development of metal-organic framework (MOF) crystal-glass composites (CGCs) has been hindered by the scarcity of MOF glass matrices with low glass transition temperatures (Tgs). Here, we investigate a CGC consisting of a low-Tg MOF glass, (agZIF-UC-7) and UiO-66. Powder X-ray diffraction and stability tests in…
Noor Abu Jarad, Jeffrey I Weitz, Tohid Didar
Improving the performance of blood-contacting medical implants is a global health necessity aimed at reducing mortality and morbidity in patients with cardiovascular diseases. Surface modification of the biomaterials from which the implants are constructed has been used to reduce the risk of complications such as…