22 papers · ranked by Valyu relevance
Seyed Mehran Kazemi, Bahare Fatemi, Alexandra Kim, Zilun Peng + 4 more
'Moumita Roy Tora' 'Xing Zeng' 'Matthew Dirks' 'David Poole'] Relational probabilistic models have the challenge of aggregation, where one variable depends on a population of other variables. Consider the problem of predicting gender from movie ratings; this is challenging because the number of movies per user and…
Juntao Wang, Yang Liu, Yiling Chen
Crowdsourcing enables the solicitation of forecasts on a variety of prediction tasks from distributed groups of people. How to aggregate the solicited forecasts, which may vary in quality, into an accurate final prediction remains a challenging yet critical problem. Studies have found that weighing expert forecasts…
Zohreh Zahedi, Rodrigo Costas, Cassidy Rose Sugimoto
The data collection and reporting approaches of four major altmetric data aggregators are studied. The main aim of this study is to understand how differences in social media tracking and data collection methodologies can have effects on the analytical use of altmetric data. For this purpose, discrepancies in the…
Henry R. O’Donnell, Tia A. Tummino, Conner Bardine, Charles S. Craik + 1 more
To fight the SARS-CoV-2 pandemic, much effort has been directed toward drug repurposing, testing investigational and approved drugs against several viral or human proteins in vitro. Here we investigate the impact of colloidal aggregation, a common artifact in early drug discovery, in these repurposing screens. We…
Keivan Mallahi-Karai, Pedram Safari
Siegel's paradox is a fundamental question in international trade about exchange rates for futures contracts and has puzzled many scholars for over forty years. The unorthodox approach presented in this article leads to an arbitrage-free solution which is invariant under currency re-denominations and is symmetric, as…
Yoonsang Lee, Howard Yen, Xi Ye, Danqi Chen
We study parallel test-time scaling for long-horizon agentic tasks such as agentic search and deep research, where multiple rollouts are generated in parallel and aggregated into a final response. While such scaling has proven effective for chain-of-thought reasoning, agentic tasks pose unique challenges: trajectories…
Tania Szal, Shweta Singh Chauhan, Philipp Lewe, Fatima-Zahra Rachad + 6 more
Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium. Therefore, small molecules interfering with efflux pump function are considered adjuvants for improving antimicrobial therapies. Several…
Annalisa Appice, Grigorios Tsoumakas, Yannis Manolopoulos, Stan Matwin + 3 more
'Stan Matwin' 'Oghenejokpeme I. Orhobor' 'Larisa N. Soldatova' 'Ross D. King'] Ensemble learning has been shown to significantly improve predictive accuracy in a variety of machine learning problems. For a given predictive task, the goal of ensemble learning is to improve predictive accuracy by combining the predictive…
František Zapletal, Miroslav Hudec, Miloš Švaňa, Radek Němec
Valuable information for decision-making can be obtained by collecting and analyzing opinions from diverse stakeholder or respondent groups, which usually have different backgrounds and are variously affected by the topics under survey. For this to succeed, it is necessary to manage the uncertainty of respondents’…
Yuqi Zhou, Atsushi Yasumoto, Cheng Lei, Chun-Jung Huang + 6 more
Platelets are anucleate cells in blood whose principal function is to stop bleeding by forming aggregates for hemostatic reactions. In addition to their participation in physiological hemostasis, platelet aggregates are also involved in pathological thrombosis and play an important role in inflammation…
Jacob Aaron Klickstein, Sirisha Mukkavalli, Malavika Raman
Protein quality control is maintained by a number of integrated cellular pathways that monitor the folding and functionality of the cellular proteome. Defects in these pathways lead to the accumulation of misfolded or faulty proteins that may become insoluble and aggregate over time. Protein aggregates significantly…
Göklem Üner, Erdal Bedir, Onur Serçinoğlu, Petek Ballar Kırmızıbayrak
Induction of distinct cell death pathways is critical to deal with tumor heterogeneity and therapeutic resistance. In our previous study, we reported a promising saponin analog (AG-08) for cancer therapy inducing non-canonical necrotic cell death. Here, we describe that AG-08 forms unique supramolecular structures…
Omri Koshorek, Niv Granot, Aviv Alloni, Shahar Admati + 6 more
Retrieval-Augmented Generation (RAG) has become the dominant approach for answering questions over large corpora. However, current datasets and methods are highly focused on cases where only a small part of the corpus (usually a few paragraphs) is relevant per query, and fail to capture the rich world of aggregative…
Itai Areili, Yakov Babichenko, Rann Smorodinsky
Bayesian experts who are exposed to different evidence often make contradictory probabilistic forecasts. An aggregator, ignorant of the underlying model, uses this to calculate her own forecast. We use the notions of scoring rules and regret to propose a natural way to evaluate an aggregation scheme. We focus on a…
Peng Meng, Andreis Lau, Daigo Miyajima, Parvej Alam + 2 more
In the past two decades, the advancement of aggregation-induced emission (AIE) has greatly advanced our understanding of organic luminescence and facilitated the application of organic luminescent materials. AIEgens emit weakly in solutions but strongly in aggregated states. This significant difference in luminescence…
Authors not listed
In this work, we present two alternative computational strategies to determine the populations of non-bonded aggregates. One approach extracts these populations from molecular dynamics (MD) simulations, while the other employs quantum mechanical partition functions for the most relevant minima of the multimolecular…
Lakshani Weerarathna, Oliver Weismantel, Tanja Junkers
A fully automated robotic synthesizer for the screening of amphiphilic block copolymer nanoparticle synthesis is presented. To reach this aim, block copolymer solutions are mixed in continuous flow with water, allowing for the automated variation of overall polymer concentration, mixing ratio of the water and organic…
Juliette Griffié, Ruby Peters, Dylan M. Owen
Molecular clustering at the plasma membrane has long been identified as a key process and is associated with regulating signalling pathways across cell types. Recent advances in microscopy, in particular the rise of super-resolution, have allowed the experimental observation of nanoscale molecular clusters in the…
Parth S. Mehta, Prasenjit Majumder
> Abstract. Multi-document summarization has received a great deal of attention in the past couple of decades. Several approaches have been proposed, many of which perform equally well and it is becoming increasingly difficult to choose one particular system over another. An ensemble of such systems that is able to…
Federico Ottomano, Giovanni De Felice, Vladimir Gusev, Taylor Sparks
Recent Machine Learning (ML) developments have opened new perspectives on accelerating the discovery of new materials. However, in the field of materials informatics, the performance of ML estimators is heavily limited by the nature of the available training datasets, which are often severely restricted and unbalanced.…
Kalil Bernardino
Due to their physical properties including high thermal stability, very low vapor pressure and high microwave absorption, ionic liquids have attracted great attention as solvents for the synthesis of nanomaterials, being considered as greener alternatives to traditional solvents. While usual solvents often need…
Fabrizio Celli, Johannes Keizer, Yves Jaques, Stasinos Konstantopoulos + 1 more
'Stasinos Konstantopoulos' 'Dušan Vudragović'] The social media revolution is having a dramatic effect on the world of scientific publication. Scientists now publish their research interests, theories and outcomes across numerous channels, including personal blogs and other thematic web spaces where ideas, activities…