26 papers · ranked by Valyu relevance
Shao-Hung Chan, Shuenn-Yuh Lee, Qiang Fang, Huimin Ma
This special issue of the Journal of Medical and Biological Engineering highlights the field of advanced bioelectronics and bioinformatics. Several papers were considered for this special issue, including those on bioelectronics in wearable and implantable medical devices, such as sensors, and bioinformatics in…
Omolara Adenaike, Olufemi Emmanuel Olabanjo, Ayansewa Adeleke Adedeji
The employability of young graduates has gained increasing significance in the labour market of the 21st century. Universities turn out millions of graduates annually, but at the same time, employers highlight their lack of the requisite skills for sustainable employment. We live today in a world of data, and therefore…
Antony T. Vincent, Steve J. Charette
The bioinformatics Like microscopes and thermal cyclers, computers are routinely used in many laboratories. Bioinformatics is a recent scientific discipline that has undergone strong and rapid progression and evolution (Ouzounis, [12]). The use of bioinformatics analyses in biological studies in fields as diverse as…
Khalid Raza
In recent years, rapid developments in genomics and proteomics have generated a large amount of biological data. Drawing conclusions from these data requires sophisticated computational analyses. Bioinformatics, or computational biology, is the interdisciplinary science of interpreting biological data using information…
Dagoberto Armenta-Medina, Christian Díaz de León-Castañeda, Brenda Valderrama-Blanco, Mariagrazia Benassi
'Brenda Valderrama-Blanco' 'Mariagrazia Benassi'] In this work, we present a diagnostic analysis of strengths, weaknesses, opportunities and threats (SWOT) of the current state of Bioinformatics in Mexico. We conducted semi-structured interviews among researchers and academics with key expertise in this field…
Clément Levin, Emeric Dynomant, Bruno J. Gonzalez, Laurent Mouchard + 3 more
'David Landsman' 'Eivind Hovig' 'Kristian Vlahoviček'] omicX, Seine Innopolis, 72 rue de la Republique, 76140 Le-Petit-Quevilly, France. Normandie Univ, INSA Rouen, LITIS, 76000 Rouen, France. Département d'Informatique et d'Information Médicales, D2IM, CHU de Rouen, France. Normandie Univ, UNIROUEN, Inserm U1245 and…
Abhishek Agarwal, Piyush Agrawal, Aditi Sharma, Vinod Kumar + 2 more
IndiaBioDb (https://webs.iiitd.edu.in/raghava/indiabiodb/) is a manually curated comprehensive repository of bioinformatics resources developed and maintained by Indian researchers. This repository maintains information about more than 550 freely accessible functional resources that include around 263 biological…
Adeeb Noor, Othman Soufan
Background Bioinformatics software is developed for collecting, analyzing, integrating, and interpreting life science datasets that are often enormous. Bioinformatics engineers often lack the software engineering skills necessary for developing robust, maintainable, reusable software. This study presents review and…
Arshia Rehman, Saeeda Naz, Imran Razzak
Clinicians decisions are becoming more and more evidence-based meaning in no other field the big data analytics so promising as in healthcare. Due to the sheer size and availability of healthcare data, big data analytics has revolutionized this industry and promises us a world of opportunities. It promises us the power…
Anne E. Kruchten
Biologists with bioinformatic skills will be better prepared for the job market, but relatively few biology programs require bioinformatics courses. Inclusion in the curriculum may be hindered by several barriers, including lack of faculty expertise, student resistance to computational work, and few examples in the…
Gilderlanio Santana de Araújo
Teaching computer programming is not a simple task and it is challenging to introduce the concepts of programming in graduate programs of other fields. Little efforts have been made on engaging students in computational development after programming trainings. An emerging need is to establish subjects of bioinformatics…
P Bryan Heidorn, Carole L Palmer, Dan Wright
Data management and integration are complicated and ongoing problems that will require commitment of resources and expertise from the various biological science communities. Primary components of successful cross-scale integration are smooth information management and migration from one context to another. We call for…
Murilo Montanini Breve, Matheus Henrique Pimenta-Zanon, Fabrício Martins Lopes
'Fabrício Martins Lopes'] Abstract—The discovery of nucleic acids and the structure of DNA have brought considerable advances in the understanding of life. The development of next-generation sequencing technologies has led to a large-scale generation of data, for which computational methods have become essential for…
B. Hesper, Paulien Hogeweg
What kind of theory we gain from the scientific study of systems strongly depends on our choice of model. By 'model' we here mean a representation of the aspects that currently interest us of the studied object, in a form that is tractable for analysis. For example: when we are interested in the interactions between…
A. C. Gorakshakar, K. Ghosh
Bioinformatics is a relatively new discipline. It is a field of science in which Computer science, Mathematics, Molecular biology and Information technology merges to form a single discipline. Database development, sequence alignment, protein structure prediction, RNA folding, evolutionary tree construction are some of…
Emanuel Diamant
- In the last few decades or so, we witness a paradigm shift in our nature studies – from a data-processing based computational approach to an information-processing based cognitive approach. The process is restricted and often misguided by the lack of a clear understanding about what information is and how it should…
Yuka Yoshimura, Akifumi Hamada, Yohann Augey, Manato Akiyama + 1 more
Biological sequence classification is the most fundamental task in bioinformatics analysis. For example, in metagenome analysis, binning is a typical type of DNA sequence classification. In order to classify sequences, it is necessary to define sequence features. The k-mer frequency, base composition, and…
Chonghuan Zhang, Qianyue Zhang, Alexei Lapkin
Biochemical transformations may allow significant improvements in synthetic efficiency of complex functional molecules through reduction in the number of synthetic steps or avoidance of harsh conditions and/or toxic solvents/reactants. Yet, there is a limited access to biochemical reaction data, which reduces the…
Luiz Gadelha, Pedro C. de Siracusa, Artur Ziviani, Eduardo Dalcin + 9 more
'Helen Michelle de Jesus Affe' 'Marinez Ferreira de Siqueira' 'Luís Alexandre Estevão da Silva' 'Douglas A. Augusto' 'Eduardo Krempser' 'Márcia Chame' 'Raquel L. Costa' 'Pedro Milet Meirelles' 'Fabiano L. Thompson'] > 1National Laboratory for Scientific Computing, Petrópolis, Brazil 2Rio de Janeiro Botanical Garden…
Michael C. Schatz
The last 20 years have been a remarkable era for biology and medicine. One of the most significant achievements has been the sequencing of the first human genomes, which has laid the foundation for profound insights into human genetics, the intricacies of regulation and development, and the forces of evolution.…
Rebecca Brunk, Kriti Shukla, Bryant Hutson, Yue Wang + 7 more
Genomic sequencing and other big biological data is unquestionably of paramount value, however the success in recruiting highly skilled individuals with diverse backgrounds has been limited. A main reason for this deficiency could be due to the lack of educational resources and early exposure to the field. With the…
Authors not listed
Untargeted metabolomics is a powerful approach for exploring the chemical diversity and dynamics of biological systems. However, the types of questions that can be addressed depend not only on experimental design but also on the data processing and analysis workflows employed, many of which require advanced…
Elaina Graham, John Heidelberg, Benjamin Tully
Metagenomics has become an integral part of defining microbial diversity in various environments. Many ecosystems have characteristically low biomass and few cultured representatives. Linking potential metabolisms to phylogeny in environmental microorganisms is important for interpreting microbial community functions…
Eric W Deutsch, Juan Antonio Vizcaíno, Andrew R Jones, Pierre-Alain Binz + 25 more
The Human Proteome Organization (HUPO) Proteomics Standards Initiative (PSI) has been successfully developing guidelines, data formats, and controlled vocabularies (CVs) for the proteomics community and other fields supported by mass spectrometry since its inception twenty years ago. Here we describe the general…
Maia I Kelly, Christopher Ashwood
Glycans are sugar-based polymers found to modify biomolecules including lipids and proteins, as well as occur unconjugated as free polysaccharides. Due to their ubiquitous cellular presentation, glycans mediate crucial biological processes and are frequently sought after as biomarkers for a wide range of diseases.…
Authors not listed
One Health seeks to integrate and balance the health of humans, animals, and environmental systems. These three spheres are intricately interconnected through microbiomes, which are universally present and exchange microbes and genes, influencing not only human and animal health but also key environmental…