26 papers · ranked by Valyu relevance
Kalyan Saginala, Adam Barsouk, John Sukumar Aluru, Prashanth Rawla + 2 more
'Sandeep Anand Padala' 'Alexander Barsouk'] Based on the latest GLOBOCAN data, bladder cancer accounts for 3% of global cancer diagnoses and is especially prevalent in the developed world. In the United States, bladder cancer is the sixth most incident neoplasm. A total of 90% of bladder cancer diagnoses are made in…
Chao-Zhe Zhu, Hua-Nong Ting, Kwan-Hoong Ng, Teng-Aik Ong
Background and purpose: Bladder cancer is the most common malignant tumour in the urinary system, with a high incidence and recurrence rate. While the incidence of bladder cancer has been rising in recent years, the prevalence of bladder carcinoma is showing an increasing tendency in the younger age group. There are…
Alexander Muacevic, John R Adler, Sattam A Halaseh, Shahed Halaseh + 3 more
'Yaman Alali' 'Mohannad E Ashour' 'Mohammad J Alharayzah'] Bladder cancer is any tumor that originates in the urinary bladder. It is the most prevalent tumor of the urinary system, with urothelial carcinoma being the most prevalent histologic subtype. It impacts both men and women. The development of bladder cancer was…
Hugo Klempfner, Paul Anderson
1## INTRODUCTION 1.1### bladder Cancer Bladder cancer (BCa) is the ninth most diagnosed cancer worldwide, accounting for 3% of all cancer diagnoses with over 550 000 incidences in 2018, a notable increase from 430 000 in 2012. Its high recurrence rates and significant morbidity contribute to BCa having one of the…
Martina Minoli, Thomas Cantore, Mirjam Kiener, Tarcisio Fedrizzi + 11 more
Bladder Cancer (BLCa) inter-patient heterogeneity is considered the primary cause of tumor reoccurrence and treatment failure, suggesting that BLCa patients could benefit from a more personalized treatment approach. Patient-derived organoids (PDOs) have been successfully used as a functional model for predicting drug…
Jillian Marie Walker, Padraic O’Malley, Mei He, Cristina Manuela Drăgoi + 2 more
'Cristina Manuela Drăgoi' 'Alina Crenguța Nicolae' 'Ion-Bogdan Dumitrescu'] Muscle Invasive Bladder Cancer (MIBC) is a subset of bladder cancer with a significant risk for metastases and death. It accounts for nearly 25% of bladder cancer diagnoses. A diagnostic work-up for MIBC is inclusive of urologic evaluation…
Jinliang Yu, Xie, Mingduo, Yue Wang + 3 more
Methods: Leveraging recent advancements in deep learning, this study proposes an integrated multitask deep learning framework specifically designed for bladder cancer diagnosis from cystoscopic images. Our framework includes a robust classification model using EfficientNet-B0 enhanced with Convolutional Block Attention…
Saram Abbas, Dr Rishad Shafik, Prof Naeem Soomro, Prof Rakesh Heer + 1 more
Bladder Cancer Recurrence Prediction Authors: ['Saram Abbas' 'Dr Rishad Shafik' 'Prof Naeem Soomro' 'Prof Rakesh Heer' 'Dr Kabita Adhikari'] Abstract—Bladder cancer, the leading urinary tract cancer, is responsible for 15 deaths daily in the UK. This cancer predominantly manifests as non-muscle-invasive bladder cancer…
Zhi-wen Cao, Yue-yi Chen, Nan-xi Fu, Fu-rui Fu + 3 more
Cell death mechanisms offer therapeutic strategies for bladder cancer, yet lack comprehensive bibliometric analysis. Map global research trends and hotspots in bladder cancer cell death mechanisms via bibliometrics. We analyzed 5,392 publications (1991–2024) from Web of Science using VOSviewer (co- authorship/keyword…
Savantha Thenuwara, Ben Schneider, Allison Mosichuk, Vojtech Gabriel + 11 more
Bladder cancer is the ninth most common malignancy in the world. Transitional cell carcinoma (TCC), also referred to as urothelial carcinoma (UC) is the most common form of bladder cancer, occurring in 90% of cases. In this study, we explore urine-derived, 3-dimensional, canine TCC organoids as a possible model to…
Takuji Tanaka, Katsuhito Miyazawa, Tetsuya Tsukamoto, Toshiya Kuno + 1 more
'Koji Suzuki'] Our understanding of the pathogenesis of bladder cancer has improved considerably over the past decade. Translating these novel pathobiological discoveries into therapies, prevention, or strategies to manage patients who are suspected to have or who have been diagnosed with bladder cancer is the ultimate…
Gabriel Garcı́a, Anna Esteve, Adrián Colomer, David Ramos + 1 more
'Valery Naranjo'] Recently, bladder cancer has been significantly increased in terms of incidence and mortality. Currently, two subtypes are known based on tumour growth: non-muscle invasive (NMIBC) and muscle-invasive bladder cancer (MIBC). In this work, we focus on the MIBC subtype because it is of the worst…
Garima Singh, Anil Kumar, Lalit Kumar, Neelu Mishra + 6 more
miRNAs represent a transformative advancement in both research and clinical management of urinary bladder cancer (UBC), emerging as clinically significant molecular targets with the potential to revolutionize existing diagnostic standards. This study exploited the robust stability of miRNAs and profiled urinary miRNAs…
Mengni Yang, Rui Li, Yu Dong, Mengting Zhou + 3 more
Bladder cancer (BC), particularly muscle-invasive and metastatic disease, remains a major clinical challenge despite recent advances in immunotherapy. In this study, we aimed to identify a promising antitumor compound from five candidate small molecules and to explore its potential roles in BC progression. Through…
Victoria Vitti Gambim, Renee Laufer-Amorim, Ricardo Fonseca Alves, Valeria Grieco + 1 more
Canine and human bladder cancer present several similar anatomical, morphological and molecular characteristics and dogs can be considered a model for human bladder cancer. However, the veterinary literature lacks information regarding cross validation analysis between human and canine large-scale data. Therefore, this…
Zihan Zhao, Ning Jiang, Yulin Zhang, Yuhao Bai + 4 more
Bladder cancer (BLCA) is one of the most common malignant tumors of the urinary system, but current therapeutic strategy based on chemotherapy and immune checkpoint inhibitors (ICIs) therapy cannot meet the treatment needs, which mainly owing to the endogenous or acquired apoptotic resistance of cancer cells. Targeting…
Mark Bandyk, Dheeraj Reddy Gopireddy, Chandana Lall, K.C. Balaji + 1 more
'José Dolz'] Precise determination and assessment of bladder cancer (BC) extent of muscle invasion involvement guides proper risk stratification and personalized therapy selection. In this context, segmentation of both bladder walls and cancer are of pivotal importance, as it provides invaluable information to stage…
Ahmad Umar, Buhari Ibrahim, Mustapha Mohammed, Ahmed Faris Aldoghachi + 11 more
Cancer biomarkers are biological molecules available in tissues, body fluids, or blood that helps in cancer prognosis, diagnosis, prediction of response to treatment, and monitoring disease progression (86, 87). To date, there have been several studies conducted to determine potential bladder cancer biomarkers in order…
Elizaveta Savchenko, Svetlana Bunimovich‐Mendrazitsky
In today's complex healthcare landscape, the pursuit of delivering optimal patient care while navigating intricate economic dynamics poses a significant challenge for healthcare service providers (HSPs). In this already complex dynamics, the emergence of clinically promising personalized medicine based treatment aims…
Tala Jouma Alhejazi, Hassan Bdeiwi, Mohamad W. Sukkari, Mohamad Ibrahim + 2 more
'Mohamad Ibrahim' 'Ammar Sukari' 'Hani Alloush'] Title: Abstract Although treated appropriately, bladder cancer can recur and metastasize. We are reporting the case of a patient with a well-cured bladder cancer who presented after 14 months with femoral pain which turned out to be a bony metastasis. The patient…
Andrea M. Tomko, Erin G. Whynot, Denis J. Dupré
With the legalization of cannabis in multiple jurisdictions throughout the world, a larger proportion of the population consumes cannabis. Several studies have demonstrated anti-tumor effects of components present in cannabis in different models. Unfortunately, little is known about the potential anti-tumoral effects…
Authors not listed
Immuno-oncology, a rapidly evolving field at the forefront of cancer research, leverages the body’s immune system to fight cancer. In this follow up report, we extend our natural language processing (NLP)-based analysis to pinpoint the context of emergence of the previously identified emerging concepts. To achieve this…
Kavita Iyer, Julian Ivanov, Rumiana Tenchov, Krittika Ralhan + 4 more
Rapid and sustained growth in the field of immuno-oncology has resulted in expansion of available scientific literature. Gaining valuable insights and establishing deep and often hidden meaningful connections in such a large body of work is the need of the hour. In this report we summarize our findings from a novel…
Authors not listed
Cancer is highly complex, including cross-talks between signalling pathways and multiple genes. Fortunately, successful anti-cancer drugs, such as cisplatin, are promising to treat cancer. Despite its clinical success, cisplatin presents several issues, including neurotoxicity, ototoxicity, nephrotoxicity and drug…
Yuan Ge, Donal O'Shea
The term “fluorescence” was first proposed nearly two centuries ago, yet its application in Medicine has a relatively brief history of only 70 years. Nowadays, as fluorescence was gradually approaching into more medicine studies, fluorescence image-guided surgery has become the new arena for this technology. It allows…
Rumiana Tenchov, Aparna Sapra, Janet Sasso, Krittika Ralhan + 3 more
Cancer is one of the leading causes of death worldwide. Early cancer detection is critical because it can significantly improve treatment outcome thus saving lives, reducing suffering, and lessening psychological and economic burdens. Cancer biomarkers provide varied information about cancer, from early detection of…