22 papers · ranked by Valyu relevance
Tijl Grootswagers, Susan G. Wardle, Thomas A. Carlson
Multivariate pattern analysis (MVPA) or brain decoding methods have become standard practice in analysing fMRI data. Although decoding methods have been extensively applied in Brain Computing Interfaces (BCI), these methods have only recently been applied to timeseries neuroimaging data such as MEG and EEG to address…
Rosy Southwell, Candida Tufo, Maria Chait
In classical studies of auditory pattern learning, neuronal responses exhibit repetition suppression, where sequences of repeated tones show a reduced evoked response. This may be due in part to adaptation, but is also hypothesized to indicate suppression of expected stimuli. Repetition suppression is thought to form a…
Shinho Cho, Hoon-Ki Min, William S. Gibson, Myung-Ho In + 2 more
Functional magnetic resonance imaging (fMRI) concurrently conducted with the deep brain stimulation (DBS) has shown that diffuse BOLD activation occurred not only near stimulation locus, but in multiple brain networks, supporting that network-wide modulation would underlie its therapeutic effect. While the extent and…
MinKyung Kim, UnCheol Lee
Brains in sleep, anesthesia, and traumatic injury are characterized by significantly limited responsiveness to stimuli. Even during conscious wakefulness, responsiveness is highly dependent on on-going brain activity, specifically, of alpha oscillations (∼10Hz). However, despite many empirical studies, the ways in…
Taylor Bolt, Jason S. Nomi, B. T. Thomas Yeo, Lucina Q. Uddin
Decades of cognitive neuroscience research have revealed two basic facts regarding task-driven brain activation patterns. First, distinct patterns of activation occur in response to different task demands. Second, a superordinate, dichotomous pattern of activation/de-activation, is commonly observed across a variety of…
Michaël E Belloy, Jacob Billings, Anzar Abbas, Amrit Kashyap + 8 more
'Wen-Ju Pan' 'Rukun Hinz' 'Verdi Vanreusel' 'Johan Van Audekerke' 'Annemie Van der Linden' 'Shella D Keilholz' 'Marleen Verhoye' 'Georgios A Keliris'] Title: Abstract How do intrinsic brain dynamics interact with processing of external sensory stimuli? We sought new insights using functional magnetic resonance imaging…
Daniel Golkowski, Rebecca Willnecker, Jennifer Rösler, Andreas Ranft + 3 more
'Gerhard Schneider' 'Denis Jordan' 'Rüdiger Ilg'] The neurophysiology of the subjective sensation of being conscious is elusive; therefore, it remains controversial how consciousness can be recognized in patients who are not responsive but seemingly awake. During general anesthesia, a model for the transition between…
Emmanuelle Tognoli, Daniela Benites, J. A. Scott Kelso
— The functioning of an organ such as the brain emerges from interactions between its constituent parts. Further, this interaction is not immutable in time but rather unfolds in a succession of patterns, thereby allowing the brain to adapt to constantly changing exterior and interior milieus. This calls for a framework…
Başak Türker, Dragana Manasova, Benoît Béranger, Lionel Naccache + 2 more
'Claire Sergent' 'Jacobo D. Sitt'] The neuroscience of consciousness aims to identify neural markers that distinguish brain dynamics in healthy individuals from those in unconscious conditions. Recent research has revealed that specific brain connectivity patterns correlate with conscious states and diminish with loss…
L. Bonetti, E. Brattico, S.E.P. Bruzzone, G. Donati + 4 more
Pattern recognition is a major scientific topic. Strikingly, while machine learning algorithms are constantly refined, the human brain emerges as an ancestral biological example of such complex procedure. However, how it transforms sequences of single objects into meaningful temporal patterns remains elusive. Using…
Jeremy R. Manning
> Abstract. Identifying stimulus-driven neural activity patterns is critical for studying the neural basis of cognition. This can be particularly challenging in intracranial datasets, where electrode locations typically vary across patients. This chapter first presents an overview of the major challenges to identifying…
Johanna Norrlid, Jonas M. D. Enander, Hannes Mogensen, Henrik Jörntell
'Henrik Jörntell'] The brain has a never-ending internal activity, whose spatiotemporal evolution interacts with external inputs to constrain their impact on brain activity and thereby how we perceive them. We used reproducible touch-related spatiotemporal sensory inputs and recorded intracellularly from rat…
Mario Garcés, Lucila Finkel
In recent decades, the existence of a close relationship between emotional phenomena and rational processes has certainly been established, yet there is still no unified definition or effective model to describe them. To advance our understanding of the mechanisms governing the behavior of living beings, we must…
Roger Orpwood
Re-entrant feedback, either within sensory cortex or arising from prefrontal areas, has been strongly linked to the emergence of consciousness, both in theoretical and experimental work. This idea, together with evidence for local micro-consciousness, suggests the generation of qualia could in some way result from…
Amanda K. Robinson, Anina N. Rich, Alexandra Woolgar
The human brain is extremely flexible and capable of rapidly selecting relevant information in accordance with task goals. Regions of frontoparietal cortex flexibly represent relevant task information such as task rules and stimulus features when participants perform tasks successfully, but less is known about how…
Semir Zeki, Oliver J. Hulme, Barrie Roulston, Michael Atiyah + 1 more
'Ernest Greene'] In the work reported here, we set out to study the neural systems that detect predictable temporal patterns and departures from them. We used functional magnetic resonance imaging (fMRI) to locate activity in the brains of subjects when they viewed temporally regular and irregular patterns produced by…
Mark H. Histed
cortex Authors: ['Mark H. Histed'] Our brains encode many features of the sensory world into memories: we can sing along with songs we have heard before, interpret spoken and written language composed of words we have learned, and recognize faces and objects. Where are these memories stored? Each area of the cerebral…
Kieran Greer
- This paper describes a new mechanism that might help with defining pattern sequences, by the fact that it can produce an upper bound on the ensemble value that can persistently oscillate with the actual values produced from each pattern. With every firing event, a node also receives an on/off feedback switch. If the…
Mohammadreza Edalati, Mahdi Mahmoudzadeh, Javad Safaie, Fabrice Wallois + 1 more
'Fabrice Wallois' 'Sahar Moghimi'] Abstract- Rhythm processing involves building expectations according to the hierarchical temporal structure of auditory events. Although rhythm processing has been addressed in the context of predictive coding, the properties of the oscillatory response in different cortical areas is…
Authors not listed
Molecular mechanisms governing initiation steps of the assembly of thousands of endogenous multi-protein complexes (EMCs) remain incompletely understood. Here, multiple lines of observations are reported reflecting the biological functions-aligned initiation sequence of hybrid assembly pathways (HAPs) of EMCs. HAPs…
Yuanmo Wang, Ajay Pradhan, Pankaj Gupta, Jörg Hanrieder + 2 more
Acetylcholine (ACh) is a critical neurotransmitter influencing various neurophysiological functions. Despite its significance, there is a lack of quantitative methods with adequate spatiotemporal resolution for recording single exocytotic efflux of ACh. In this study, we present an ultrafast amperometric ACh biosensor…
Koichi Handa, Daichi Fujita, Mariko Hirano, Saki Yoshimura + 2 more
Given the aging populations in advanced countries globally, many pharmaceutical companies have focused on developing central nervous system (CNS) drugs. However, due to the blood-brain barrier, drugs do not easily reach the target area in the brain. Although conventional screening methods for drug discovery involve the…