22 papers · ranked by Valyu relevance
Qiuyi Liu, Lili Sun, Xinyi Zhao, Wenbin Qu + 5 more
Understanding how large-scale brain networks dynamically coordinate during complex, real-world experiences remains a crucial topic in contemporary neuroscience. Leveraging naturalistic paradigm, this study employed energy landscape modeling to characterize the temporal dynamics of brain state transitions and their…
Alexander Poltorak
Brain states, which correlate with specific motor, cognitive, and emotional states, may be monitored with noninvasive techniques such as electroencephalography (EEG) and magnetoencephalography (MEG) that measure macroscopic cortical activity manifested as oscillatory network dynamics. These rhythmic cortical signatures…
Irene Rembado, David K. Su, Ariel Levari, Larry E. Shupe + 3 more
Vagus nerve stimulation (VNS) is tested as therapy for several brain disorders and as a means to modulate brain plasticity. Cortical effects of VNS, manifesting as vagal-evoked potentials (VEPs), are thought to arise from activation of ascending cholinergic and noradrenergic systems. However, it is unknown whether…
Piergiorgio Salvan, Alberto Lazari, Diego Vidaurre, Francesca Mandino + 2 more
'Francesca Mandino' 'Heidi Johansen-Berg' 'Joanes Grandjean'] Title: Summary Human neuroimaging studies have shown that, during cognitive processing, the brain undergoes dynamic transitions between multiple, frequency-tuned states of activity. Although different states may emerge from distinct sources of neural…
Jörn M. Horschig, Johanna M. Zumer, Ali Bahramisharif
Cortical oscillations have been shown to represent fundamental functions of a working brain, e.g., communication, stimulus binding, error monitoring, and inhibition, and are directly linked to behavior. Recent studies intervening with these oscillations have demonstrated effective modulation of both the oscillations…
Natalie Schaworonkow, Jochen Triesch, Ulf Ziemann, Christoph Zrenner
Corticospinal excitability depends on the current brain state. The recent development of real-time EEG-triggered transcranial magnetic stimulation (EEG-TMS) allows studying this relationship in a causal fashion. Specifically, it has been shown that corticospinal excitability is higher during the scalp surface negative…
Paul Schmid, Timon Klein, Piotr Minakowski, Sebastian Sager + 3 more
We investigated the effects of brain states on human perception and early visual response comparing focused wakefulness (ON state) to external inattention (OFF state). In two experiments, we investigated the temporal kinetics of brain states changes during stimulus processing and assessed fluctuations across extended…
MinKyung Kim, Richard E. Harris, Alexandre F. DaSilva, UnCheol Lee
Fibromyalgia (FM) is a chronic pain condition that is characterized by hypersensitivity to multimodal sensory stimuli, widespread pain, and fatigue. We have previously proposed explosive synchronization (ES), a phenomenon wherein a small perturbation to a network can lead to an abrupt state transition, as a potential…
Mohammad-Reza Zarrindast, Fatemeh Khakpai
There is much evidence demonstrating that not only state-dependent memory is produced by the systemic administration of drugs but also is induced by the injection of drugs into the various brain areas. Several studies in our laboratory revealed that various neurotransmitter mechanisms, e.g., glutamatergic, GABAergic…
Milena Čukić, Miodrag Stokić, Slavoljub Radenković, Miloš Ljubisavljević + 1 more
'Miloš Ljubisavljević' 'Dragoljub Pokrajac'] Transcranial direct current stimulation (tDCS) is known to have a modulatory effect on neural tissue and that it is polarity specific. It is also shown that tDCS demonstrated the lasting effect in therapeutic applications. The main aim of the study was to examine the effects…
Rodrigo Cofré, Rubén Herzog, Pedro A. M. Mediano, Juan Piccinini + 3 more
'Fernando E. Rosas' 'Yonatan Sanz Perl' 'Enzo Tagliazucchi'] - 1 CIMFAV-Ingemat, Facultad de Ingeniería 2340000, Universidad de Valparaíso, Valparaíso, Chile - 2 Centro Interdisciplinario de Neurociencia de Valparaíso 2360103, Universidad de Valparaíso, Valparaíso, Chile - 3 Department of Psychology, University of…
Tao Xie, Zehan Wu, Thomas J Foutz, Xinjun Sheng + 5 more
Objective. Slow-wave modulation occurs during states of unconsciousness and is a large-scale indicator of underlying brain states. Conventional methods typically characterize these large-scale dynamics by assuming that slow-wave activity is sinusoidal with a stationary frequency. However, slow-wave activity typically…
L. Beynel, L. Deng, C.A. Crowell, M. Dannhauer + 8 more
The brain is an inherently dynamic system, and much work has focused on the ability to modify neural activity through both local perturbations and changes in the function of global network ensembles. Network controllability is a recent concept in network science that purports to predict the influence of individual…
Authors not listed
This paper formally defines an operational isomorphism between spectral damping in molecular vibronic systems and neuromodulatory control in biological sensory systems. Without asserting causal continuity or physical identity across scales, we show that both domains instantiate the same class of output-selective…
Yang Wang, Dongrui Wu
In recent years, the rapid development of neuroimaging technology has been providing many powerful tools for cognitive neuroscience research. Among them, the functional magnetic resonance imaging (fMRI), which has high spatial resolution, acceptable temporal resolution, simple calibration, and short preparation time…
He, Jiangshan, Xie, Hui + 22 more
- 1 Center for Biomedical-photonics and Molecular Imaging, Advanced Diagnostic-Therapy Technology and Equipment Key Laboratory of Higher Education Institutions in Shaanxi Province, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710126, China; - 2 Xi'an Key Laboratory of Intelligent Sensing and…
John D. Medaglia, Perry Zurn, Walter Sinnott‐Armstrong, Danielle S. Bassett
'Danielle S. Bassett'] ∗Department of Psychology, University of Pennsylvania, Philadelphia, PA, 19104 USA,†Center for Curiousity, University of Pennsylvania, Philadelphia, PA, 19104 USA,‡Department of Philosophy, American University, Washington, DC, 20016 USA,§Department of Philosophy and Kenan Institute for Ethics…
Siddhartha Sen
In this paper a theoretical model for measuring consciousness based on experimental observations is proposed. Consciousness, the awareness of one's self and one's immediate environment, is defined, in this paper, in terms of the information about this awareness that is contained in or being processed by the brain. This…
Gagan Acharya, Sebastian F. Ruf, Erfan Nozari
Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as epilepsy, Parkinson's Disease, and depression. The provided stimulation can be of different types, such as electric, magnetic, and…
Spencer Kim, Dylan Gray, Michelle Shanguhyia, Rachel Steinhardt
Recreating the signaling profile a chemical synapse to analyze serotonin receptor activation is a challenge. This is due in part to the kinetics of the synapse, where neurotransmitters are rapidly released and quickly cleared by active reuptake machinery. One strategy to produce a rapid rise in a bio-orthogonally…
Authors not listed
The GluK1 receptor, an ionotropic glutamate receptor, operates as a ligand-gated ion channel. Opioids stand as the most potent pain-relieving medications currently prescribed in the medical field. Inhibiting this receptor is anticipated to result in a reduction of dopamine release in the Nucleus Accumbens, effectively…
Authors not listed
The therapeutic potential of cannabis remains constrained by persistent physiological side effects that limit both medical applications and user tolerability. This paper presents a theo- retical framework for addressing these limitations through coordinated multi-target pharma- cological intervention. By synthesizing…