12 papers · ranked by Valyu relevance
Qiuyi Liu, Lili Sun, Xinyi Zhao, Wenbin Qu + 5 more
Understanding how large-scale brain networks dynamically coordinate during complex, real-world experiences remains a crucial topic in contemporary neuroscience. Leveraging naturalistic paradigm, this study employed energy landscape modeling to characterize the temporal dynamics of brain state transitions and their…
Irene Rembado, David K. Su, Ariel Levari, Larry E. Shupe + 3 more
Vagus nerve stimulation (VNS) is tested as therapy for several brain disorders and as a means to modulate brain plasticity. Cortical effects of VNS, manifesting as vagal-evoked potentials (VEPs), are thought to arise from activation of ascending cholinergic and noradrenergic systems. However, it is unknown whether…
Natalie Schaworonkow, Jochen Triesch, Ulf Ziemann, Christoph Zrenner
Corticospinal excitability depends on the current brain state. The recent development of real-time EEG-triggered transcranial magnetic stimulation (EEG-TMS) allows studying this relationship in a causal fashion. Specifically, it has been shown that corticospinal excitability is higher during the scalp surface negative…
Paul Schmid, Timon Klein, Piotr Minakowski, Sebastian Sager + 3 more
We investigated the effects of brain states on human perception and early visual response comparing focused wakefulness (ON state) to external inattention (OFF state). In two experiments, we investigated the temporal kinetics of brain states changes during stimulus processing and assessed fluctuations across extended…
Maria Pfeiffer, Andrea Kübler, Kirsten Hilger
Human brain activity consists of different frequency bands associated with varying functions. Oscillatory activity of frontal brain regions in the theta range (4-8Hz) is linked to cognitive processing and can be modulated by neurofeedback - a technique where participants receive real-time feedback about their brain…
Aaron N. McInnes, Victoria L. Pipia, Kiyana L. Maynard, Güldamla Kalender + 1 more
Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for major depressive disorder (MDD), yet variability of therapeutic responses remains high. A key contributor to this variability may be state-dependent effects of brain stimulation, where activity in underlying circuits can shape the…
Zeinab Fazlali, Yadollah Ranjbar-Slamloo, Erfan Zabeh, Ehsan Arabzadeh
Locus Coeruleus (LC) noradrenergic system has widespread projections throughout the brain and affects sensory processing. LC modulation of sensory-evoked cortical activity and brain state is documented by electrical micro-stimulation, optogenetic experiments, and the local application of norepinephrine (NE). The…
Florian H. Kasten, Christoph S. Herrmann
Non-invasive techniques to electrically stimulate the brain such as transcranial direct and alternating current stimulation (tDCS/tACS) are increasingly used in human neuroscience and offer potential new avenues to treat brain disorders. However, their often weak and variable effects have also raised concerns in the…
Pavel Sanda, Jaroslav Hlinka, Monica van den Berg, Maxim Bazhenov + 2 more
Brain activity during the resting state is widely used to examine brain organization, cognition and alterations in disease states. While it is known that neuromodulation and the state of alertness impact restingstate activity, neural mechanisms behind such modulation of resting-state activity are unknown. In this work…
Daniel S. Kluger, Joachim Gross
Despite recent advances in understanding how respiration affects neural signalling to influence perception, cognition, and behaviour, it is yet unclear to what extent breathing modulates brain oscillations at rest. We acquired respiration and resting state magnetoencephalography (MEG) data from human participants to…
L. Beynel, L. Deng, C.A. Crowell, M. Dannhauer + 8 more
The brain is an inherently dynamic system, and much work has focused on the ability to modify neural activity through both local perturbations and changes in the function of global network ensembles. Network controllability is a recent concept in network science that purports to predict the influence of individual…
Ram Kumar Pari
Stroboscopic stimulation has been previously shown to induce visual hallucinations and altered states of consciousness, state by entraining the brain to the driving frequency, similar to those reported during the psychedelics although little systematic research exists on the effect of specific stimulation frequency on…