26 papers · ranked by Valyu relevance
Mona Pourjafar, Vijay K. Tiwari
Cell migration is fundamental to both development and adult physiology, including gastrulation, brain development, angiogenesis, wound healing, bone remodeling, tissue homeostasis, and the immune response. Additionally, misguided cellular migration is implicated in disease pathologies such as cancer metastasis and…
Francisco Merino-Casallo, Maria Jose Gomez-Benito, Silvia Hervas-Raluy, Jose Manuel Garcia-Aznar
'Silvia Hervas-Raluy' 'Jose Manuel Garcia-Aznar'] Title: ABSTRACT Cell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors. Cells change their migratory strategy based…
Ignacio Montenegro-Rojas, Martín Andaur-Lobos, Karol Soler, Diego Castelli-Lacunza + 3 more
The persistence of cell migration is a fundamental property of motile behavior, enabling cells to maintain directionality while adapting to fluctuations and external cues. This feature underlies essential processes such as development, immune responses, and cancer invasion. Classical mathematical models have offered…
Ayuko Sakane, Shin Yoshizawa, Hideo Yokota, Takuya Sasaki
Collective cell migration is observed during morphogenesis, angiogenesis, and wound healing, and this type of cell migration also contributes to efficient metastasis in some kinds of cancers. Because collectively migrating cells are much better organized than a random assemblage of individual cells, there seems to be a…
Laeschkir Würthner, Frederik Graw
Cell migration is a dynamic process that is of critical importance to various aspects of living organisms, including organogenesis, wound healing, and immune responses. Several external factors are known to influence and direct active cell movement, such as chemokine gradients or the composition and mechanical…
Ildefonso M. De la Fuente, Jose Carrasco-Pujante, Borja Camino-Pontes, Maria Fedetz + 6 more
Directional motility is an essential property of cells. Despite its enormous relevance in many fundamental physiological and pathological processes, how cells control their locomotion movements remains an unresolved question. Here we have addressed the systemic processes driving the directed locomotion of cells.…
Yang Hu, Matthew L. Becker, Rebecca Kuntz Willits
Cell migration plays an essential role in physiological and pathological states, such as immune response, tissue generation and tumor development. This phenomenon can occur spontaneously or it can be triggered by an external stimuli, including biochemical, mechanical, or electrical cues that induce or direct cells to…
Ildefonso M De la Fuente, Jose Carrasco-Pujante, Borja Camino-Pontes, Maria Fedetz + 7 more
'Maria Fedetz' 'Carlos Bringas' 'Alberto Pérez-Samartín' 'Gorka Pérez-Yarza' 'José I López' 'Iker Malaina' 'Jesus M Cortes' 'Horacio Espinosa'] Title: Abstract Directional motility is an essential property of cells. Despite its enormous relevance in many fundamental physiological and pathological processes, how cells…
Tian Lan, Kai Cheng, Tina Ren, Stephen Hugo Arce + 1 more
Cell migration is an essential process in organism development and physiological maintenance. Although current methods permit accurate comparisons of the effects of molecular manipulations and drug applications on cell motility, effects of alterations in subcellular activities on motility cannot be fully elucidated…
Sai P. Visweshwaran, Tanja Maritzen
Title: Graphical abstract
Ildefonso M. De la Fuente, Jose Carrasco-Pujante, Borja Camino-Pontes, Maria Fedetz + 6 more
Directional locomotion is a fundamental characteristic of many cells with great relevance in essential physiological and human pathological processes. For decades, research efforts have focused on studying specific individual processes and their corresponding biomolecular components involved in cellular locomotion…
Katsuhiko Sato
Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a cluster, referred to as cluster migration, are poorly understood. A key reason…
Theresa Jakuszeit, Mathieu Deygas, Mathilde Bernard, Aastha Mathur + 6 more
Directed migration in chemical gradients is crucial to the immune response, yet how immune cells navigate complex tissues remains incompletely understood. Using in vitro migration assays and theoretical modeling, we uncover distinct chemotactic strategies in two key immune cell types: neutrophils and dendritic cells…
Yuri Belotti, David McGloin, Cornelis J. Weijer
Neutrophils and dendritic cells have, besides their well characterised chemotactic movement responses, been shown to be able to detect and respond to local differences in hydraulic resistance (barotaxis). Furthermore, for neutrophils, it has been suggested that barotaxis overrides chemotaxis. Here, we investigate…
Jesse R. Holt, Jinghao Chen, Elizabeth L. Evans, John S. Lowengrub + 1 more
The collective migration of keratinocytes during wound healing requires both the generation and transmission of mechanical forces for individual cellular locomotion as well as for the coordination of movement across cells. Leader cells initiated along the wound edge transmit mechanical and biochemical cues to ensuing…
Előd Méhes, Tamás Vicsek
- 5 Swarming or collective motion of living entities is one of the most common and spectacular manifestations of living systems having been extensively studied in recent years. A number of general principles have been established. The interactions at the level of cells are quite different from those among individual…
Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, G Swan + 4 more
'Alex Laude' 'Majlinda Lako' 'Anvar Shukurov' 'N. G. Parker'] Abstract. We perform a detailed analysis of the migratory motion of human embryonic stem cells in two-dimensions, both when isolated and in close proximity to another cell, recorded with time-lapse microscopic imaging. We show that isolated cells tend to…
Elena Agliari, Pablo J. Sáez, Adriano Barra, Matthieu Piel + 2 more
'Pablo Vargas' 'Michele Castellana'] Migration of cells can be characterized by two, prototypical types of motion: individual and collective migration. We propose a statistical-inference approach designed to detect the presence of cell-cell interactions that give rise to collective behaviors in cell-motility…
Qiyao Peng, F.J. Vermolen, Daphne Weihs
Cancer cell migration between different body parts is the driving force behind cancer metastasis, which is the main cause of mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in locally stiff, yet flexible tissues. In our previous work, we developed a model for cell…
Arie Horowitz, Akiko Mammoto, Vladimir Sytnyk, Igor Jakovcevski
Adhesion, whether to the extracellular matrix (ECM) ([18]) or to adjacent cells ([4]; [13]) is essential for cell migration. This dependence is the focus of the current Research Topic, comprising six reviews and two original research papers. Cell movement occurs in multicellular organisms both singly and collectively…
Jiayi Liu, Javier Boix-Campos, Jonathan E. Ron, Johan M. Kux + 2 more
'Nir S. Gov' 'Pablo J. Sáez'] Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues. In another example, to properly irrigate the…
Noriyuki Uchida, Takahiro Muraoka
This article focuses on recent studies of the development of bioinspired supramolecular materials mimicking the contact events seen at the dynamic bio-interfaces. A diverse range of cellular activities occurs through the dynamic actions of biomacromolecules and supramolecular assemblies such as extracellular matrices…
Authors not listed
The ability to track therapeutic cells is critical for advancing adoptive cell therapy (ACT). Positron emission tomography (PET) offers sensitive and quantitative imaging, yet improved cell radiolabeling strategies are sorely needed. We report a metabolic glycoengineering (MGE) approach that installs azide moieties on…
Kazeem Olanrewaju, Ashlee N. Ford Versypt
The human physiological system consists of several biological units carefully organized to engage in a bio-physicochemical interaction with complex fluids transporting nutritional and life-supporting species (oxygen and carbon dioxide) needed for the proper functioning of the body. The nutritional species are products…
Mohsen Sotoudeh, Axel Gross
Ion mobility in electrolytes and electrodes is a critical factor influencing the performance of batteries. Low ion mobility is for example one of the major factors reducing the range of battery-electric vehicles in winter time. On the other hand, with respect to the ion mobility in battery cathode materials there are…
Mohsen Sotoudeh, Sebastian Baumgart, Manuel Dillenz, Johannes Döhn + 4 more
Ion mobility in electrolytes and electrodes is an important performance parameter in electrochemical devices, particularly in batteries. In this review, we concentrate on the charge carrier mobility in crystalline battery materials where the diffusion basically corresponds to hopping processes between lattice sites.…