12 papers · ranked by Valyu relevance
Alma M. N. Nederlof, Jeroen Kappelhof, Anne Marijke Schel
The social complexity hypothesis for communication posits that species with elaborate social systems require more sophisticated vocal communication to navigate social life. Geladas (Theropithecus gelada), who live in complex multilevel societies and form diverse social bonds, are ideal for testing this hypothesis.…
Joshua Justison, Gustavo A. Ballen, Carlos Acosta-Cortés, Roberto Ceja + 2 more
Phylogenetic networks extend the traditional tree model to capture reticulate evolutionary processes such as gene flow and hybridization. Among available inference tools, SNaQ is a widely used quartet-based method that offers a computationally efficient, statistically grounded approach to network estimation, but is…
Claire Chenwen Zhong, Man Kin Yim, Mingtao Chen, Chung Yi Lo + 3 more
Physicians and policymakers also viewed HA Go as environmentally friendly because it reduced reliance on paper-based and cash-based processes ([ooag133-T5]). They noted that, through an “electronic platform,” many tasks could be handled more conveniently with “less paper used” and fewer “cash transactions” [PB002].…
Cheryl Kim, Denise Hinz, Aaron Middlebrook, Aaron J Tyznik + 4 more
Circulating cell-cell complexes (doublets) provide critical insights into in vivo immune interactions. Here, we leverage high-dimensional imaging spectral cytometry to systematically map the landscape of immune doublets in human peripheral blood. By integrating morphometric imaging features with a 22-color spectral…
Sum Yi Cheong, Trevors In Zen Liew, Chee Kin Wong, Xue Xin Teng + 4 more
Lung-on-a-chip (LoAC) technology has emerged as a human-relevant microphysiological approach for respiratory disease modelling and preclinical drug evaluation. However, substantial variation in device architecture, membrane properties, fluidic conditions, mechanical actuation, cellular composition, sensing and…
Raphael Mostov, Greyson Lewis, Gabriel Sturm, Wallace F. Marshall
This paper addresses the increasing need for comprehensive mathematical descriptions of cell organization by examining the algebraic structure of mitochondrial network dynamics. Mitochondria are cellular structures involved in metabolism that take the form of a network of membrane-based tubes that undergo continuous…
Adrien E.E. Dubois, Sarah Lippé, Charles-Olivier Martin, Inga S. Knoth + 27 more
Whether the heterogeneity of psychiatric conditions converges on shared neurophysiological alterations or translates into distinct signatures remains unclear. We assembled high-density electroencephalogram (hd-EEG) resting-state recordings from 4,812 individuals aged 5 months to 66 years across 11 psychiatric…
Mirna El Ghosh, Varvara Kalokyri, Maciej Bobowicz, Melanie Sambres + 11 more
Background Semantic interoperability in health care, essential for seamless integration of information systems, is partially achieved through the use of terminologies and common data standards that define the semantic structure of data. Various complexities arise when using real-world health care data, including…
Justina Stark, Christophe Godin
Biological transport networks range from tree-like to highly reticulated architectures, which have been proposed to reflect different balances between viscous dissipation and metabolic cost. This balance cannot currently be inferred from structure: available descriptors either discard edge width entirely or preserve it…
Ana Lúcia Leitão, Francisco J Enguita
The evolution of molecular visualization software represents a pivotal yet often underappreciated dimension of computational structural biology and bioinformatics. As the scale and complexity of structural datasets increase, spanning from cryo-electron microscopy reconstructions to proteome-wide AI-predicted models…
Maryam Majeed, Mara C.P. Rue, Aixin Zhang, Sabrina Cheng + 14 more
Parallel visual streams segregate information into pathways specialized for distinct computations, but how this segregation is achieved by anatomical segregation of primary visual cortex output remains unclear. This problem is complicated because individual neurons frequently send broadcasting projections to multiple…
John Tower
Biological information is generally thought to be subject to selection for faithful maintenance. However, accurate preservation is often combined with regulated mechanisms that generate state change. Selectively advantageous instability (SAI) is modeled here as instability that is favored because useful alternatives…