20 papers · ranked by Valyu relevance
Behnaz Abdorrahimi, Atefeh Nekouie, Amir Masoud Rahmani, Jan Lansky + 3 more
'Vladimír Nulíček' 'Mehdi Hosseinzadeh' 'Mohammad Hossein Moattar'] With electronic healthcare systems undergoing rapid change, optimizing the crucial process of recording physician prescriptions is a task with major implications for patient care. The power of blockchain technology and the precision of the Raft…
Zhenyan Ji, Xiao Zhang, Jianghao Hu, Yuan Lu + 2 more
'Maurizio Talamo'] Blockchain technology can be used in the IoT to ensure the data privacy collected by sensors. In blockchain systems, consensus mechanisms are a key technology for maintaining data consistency and correctness. Among the various consensus protocols, asynchronous Byzantine consensus protocols offer…
Vittorio Capocasale, Rahul Shah
Consensus algorithms play a crucial role in facilitating decision-making among a group of entities. In certain scenarios, some entities may attempt to hinder the consensus process, necessitating the use of Byzantine fault-tolerant consensus algorithms. Conversely, in scenarios where entities trust each other, more…
Wei Yao, Fadi P. Deek, Renita Murimi, Guiling Wang
Blockchain is a distributed ledger that is decentralized, immutable, and transparent, which maintains a continuously growing list of transaction records ordered into blocks. As the core of blockchain, the consensus algorithm is an agreement to validate the correctness of blockchain transactions. For example, Bitcoin is…
Yansong Zhang, Bo Shen, Yingsi Zhao
Generally, system failures, such as crash failures, Byzantine failures, and so on, are considered as common reasons for the inconsistencies of distributed consensus and have been extensively studied. In fact, strategic manipulations by rational agents are not ignored for reaching consensus in a distributed system. In…
Xiaoxiong Wu, Wangxi Jiang, Mingyang Song, Zhenhong Jia + 1 more
The consensus algorithm is very critical in any blockchain system, because it directly affects the performance and security of the blockchain system. At present, the classic Practical Byzantine Fault Tolerance Algorithm (PBFT), which is mainly used in the consortium chain, will lead to system communication congestion…
Robbert van Renesse
Fault tolerant consensus protocols usually involve ordered rounds of voting between a collection of processes. In this paper, we derive a general specification of fault tolerant asynchronous consensus protocols and present a class of consensus protocols that refine this specification without using rounds.…
Shashank Joshi
Blockchain is a type of decentralized distributed network which acts as an immutable digital ledger. Despite the absence of any central governing authority to validate the blocks in the ledger, it is considered secure and immutable due to the consensus protocol among various nodes of the network. A consensus algorithm…
Wouter Kuijper
We propose a refinement to the well known, and widely used, proof-of-work scheme of zeroing a cryptographic hash [4, 1]. Our refinement is interesting because it allows multiple autonomous users to cooperate on the proof-of-work for their own transactions in order to bring about consensus on the order of said…
Lukas Mastilak, Pavol Helebrandt, Marek Galinski, Ivan Kotuliak + 2 more
The whole Internet consists of thousands of autonomous systems that transfer data with one another. The BGP plays a significant role in routing, but its behaviour is essentially naive, trusting neighbours without authenticating advertised IP prefixes. This is the main reason why BGP endures various path manipulation…
Robert Escriva, Robbert van Renesse
Consus is a strictly serializable geo-replicated transactional key-value store. The key contribution of Consus is a new commit protocol that reduces the cost of executing a transaction to three wide area message delays in the common case. Augmenting the commit protocol are multiple Paxos implementations optimized for…
Chenxing Li, Peilun Li, Dong Zhou, Wei Xu + 2 more
'Andrew Chi-Chih Yao'] This paper presents Conflux, a fast, scalable and decentralized blockchain system that optimistically process concurrent blocks without discarding any as forks. The Conflux consensus protocol represents relationships between blocks as a direct acyclic graph and achieves consensus on a total order…
Ana M. Daugherty, Valerie Carr, Kelsey L. Canada, Gustaf Rådman + 36 more
Hippocampal subfields differentially develop and age, and they vary in vulnerability to neurodegenerative diseases. Innovation in high-resolution imaging has accelerated clinical research on human hippocampal subfields, but substantial differences in segmentation protocols impede comparisons of results across…
Antoine Lacour, Hamza Ibrahim, Andrea Volkamer, Anna K. H. Hirsch
In this study, we introduce DockM8, an innovative open-source platform designed for consensus virtual screening in drug design. Leveraging various docking algorithms and scoring functions, DockM8 provides a highly customizable workflow for structure-based virtual screening. In rigorous evaluations across the DEKOIS…
Zhiqiang Du, Wendong Zhang, Liangxin Liu, Yanfang Fu
Sharding blockchain is a technology designed to improve the performance and scalability of traditional blockchain systems. However, due to its design, communication between shards depends on shard leaders for transmitting information, while shard members are unable to detect communication activities between shards.…
Robin de Flores, Kelsey L Canada, Thackery Brown, Nicole J Gervais + 24 more
The hippocampus is a heterogeneous structure with cytoarchitectonically distinct subfields that exhibit heterogeneous lifespan trajectories and are differentially susceptible to diseases. Advances in high-resolution imaging have accelerated research on these structures, yet variability in segmentation protocols limits…
Andreagiovanni Reina, Thomas Bose, Vaibhav Srivastava, James A. R. Marshall
It is usually assumed that information cascades are most likely to occur when an early but incorrect opinion spreads through the group. Here we analyse models of confidence-sharing in groups and reveal the opposite result: simple but plausible models of naïve Bayesian decision-making exhibit information cascades when…
Daniele Carlesso, Madelyne Stewardson, Simon Garnier, Ofer Feinerman + 1 more
Animal groups need to achieve and maintain consensus to minimise conflict among individuals and prevent group fragmentation. An excellent example of a consensus challenge is cooperative transport, where multiple individuals cooperate to move a large item together. This behavior, regularly displayed by ants and humans…
Andrea Kopp, Peter Hartog, Martin Šícho, Guillaume Godin + 1 more
The EUOS/SLAS challenge has its goal to develop reliable algorithms to predict solubility of small molecules experimentally measured aqueous solubility of 100k compounds. In total, hundred teams took part in the challenge to predict low, medium and highly soluble compounds as measured by nephelometry assay. This…
Authors not listed
Computing the free energy of protein-ligand binding by employing molecular dynamics (MD) simulations is becoming a valuable tool in the early stages of drug discovery. However, the cost and complexity of such simulations are often prohibitive for high-throughput studies. We present an automated workflow for the…