21 papers · ranked by Valyu relevance
Andrew S. LaCroix, Andrew D. Lynch, Matthew E. Berginski, Brenton D. Hoffman
Molecular tension sensors have contributed to a growing understanding of mechanobiology. However, the limited dynamic range and inability to specify the mechanical sensitivity of these sensors has hindered their widespread use in diverse contexts. Here, we systematically examine the components of tension sensors that…
Sheryl Hsu, Manda Tran, Aurore Fass
This paper is the first attempt at providing a holistic view of the Chrome Web Store (CWS). We leverage historical data provided by ChromeStats to study global trends in the CWS and security implications. We first highlight the extremely short life cycles of extensions: roughly 60% of extensions stay in the CWS for one…
Pablo Curiel, Ana B. Lago
Mobile phones enable us to carry out a wider range of tasks every day, and as a result they have become more ubiquitous than ever. However, they are still more limited in terms of processing power and interaction capabilities than traditional computers, and the often distracting and time-constricted scenarios in which…
Catia Pesquita, Francisco M. Couto, K. Bretonnel Cohen
Developing and extending a biomedical ontology is a very demanding task that can never be considered complete given our ever-evolving understanding of the life sciences. Extension in particular can benefit from the automation of some of its steps, thus releasing experts to focus on harder tasks. Here we present a…
David Buján, David Martín, Ortzi Torices, Diego López-de-Ipiña + 3 more
'Carlos Lamsfus' 'Joseba Abaitua' 'Aurkene Alzua-Sorzabal'] The notion of context has been widely studied and there are several authors that have proposed different definitions of context. However, context has not been widely studied in the framework of human mobility and the notion of context has been imported…
Authors not listed
This work presents the LabIMotion extension for the Chemotion Electronic Lab Notebook (ELN), expanding its capabilities from organic chemistry to support interdisciplinary research and enabling the description of workflows. LabIMotion enhances documentation by introducing customizable components structured across three…
Avihay Cohen
Modern software supply chains face an increasing threat from malicious code hidden in trusted components such as browser extensions, IDE extensions, and opensource packages. This paper introduces JavaSith, a novel client-side framework for analyzing potentially malicious extensions in web browsers, Visual Studio Code…
Hashai Papneja
This paper attempts to synthesize various conceptualizations of the term 'context' as found in computing literature. Ten conceptual dimensions of context thus emerge—location; user, task, and system characteristics; physical, social, organizational, and cultural environments; time-related aspects, and historical…
Daniel Duzdevich, Christopher E. Carr, Jack W. Szostak
Life emerging in an RNA world is expected to propagate RNA as hereditary information, requiring some form of primitive replication without enzymes. Nonenzymatic template-directed RNA primer extension is a model of the polymerisation step in this posited form of replication. The sequence space accessed by primer…
José Miguel Moreno, Narseo Vallina-Rodrìguez, Juan Tapiador
through Browser Extension Similarity Authors: ['José Miguel Moreno' 'Narseo Vallina-Rodrìguez' 'Juan Tapiador'] Abstract—Web browsers, particularly Google Chrome and other Chromium-based browsers, have grown in popularity over the past decade, with browser extensions becoming an integral part of their ecosystem. These…
Konrad Kollnig, Siddhartha Datta, Nigel Shadbolt
In this work, we investigate mobile app extensions, a previously underexplored concept to study and address digital harms within mobile apps in a decentralised, community-driven way. We analyse challenges to adoption of this approach so far, and present a readyto-use implementation for Android as a result of…
Samuel Genheden, Agnes Mårdh, Gustav Lahti, Ola Engkvist + 2 more
We present machine learning models for predicting the chemical context for Buchwald-Hartwig coupling reactions. Using reaction data from in-house electronic lab notebooks, we train two models: one based on single-label data and one based on multi-label data. Both models show excellent top-3 accuracy around 90%, which…
Kaisa Helttunen, Heikki Kainulainen, J. M. García-Ruiz
The design and features of the CIF extension for Visual Studio Code are presented.
Sela Ferdman, Einat Minkov, Ron Bekkerman, David Gefen + 1 more
'Hussein Suleman'] Contrary to the assumption that web browsers are designed to support the user, an examination of a 900,000 distinct PCs shows that web browsers comprise a complex ecosystem with millions of addons collaborating and competing with each other. It is possible for addons to “sneak in” through third party…
Georgios Kontonatsios, Ioannis Korkontzelos, BalaKrishna Kolluru, Paul Thompson + 1 more
'Paul Thompson' 'Sophia Ananiadou'] Background U-Compare is a text mining platform that allows the construction, evaluation and comparison of text mining workflows. U-Compare contains a large library of components that are tuned to the biomedical domain. Users can rapidly develop biomedical text mining workflows by…
Alexander Muacevic, John R Adler, Goki Kamei, Akinori Nekomoto + 3 more
Purpose There have been no reports comparing the change in medial and lateral posterior condylar offset (PCO) and the extension gaps. The purpose of this study was to elucidate the relationship between the change in medial and lateral PCO and the extension gap in total knee arthroplasty (TKA). The hypothesis is that an…
Emanuel Becerra Soto, Adam J. Oliver, Marcos H. de Moraes
The rapid expansion of bacterial genome databases presents significant opportunities for functional discovery, yet a large fraction of genes and protein domains remain uncharacterized. Analyzing genomic context and domain architecture are powerful approaches for functional inference, but existing tools often lack the…
Authors not listed
Synthetic accessibility is a key issue in the current compound generation. Unlike conventional approaches that assess synthetic accessibility after compound generation, the fragment-based method proposed in this study links the fragments in the reverse direction of the retrosynthesis analysis guaranteeing the synthetic…
Benjamin Liffner, Thiago Luiz Alves e Silva, Joel Vega-Rodriguez, Sabrina Absalon
Study of malaria parasite cell biology is challenged by their small size, which can make visualisation of individual organelles difficult or impossible using conventional light microscopy. In recent years, the field has attempted to overcome this challenge through the application of ultrastructure expansion microscopy…
Jennifer L. Chlebek, Triana N. Dalia, Nicolas Biais, Ankur B. Dalia
Bacteria utilize dynamic appendages called type IV pili (T4P) to interact with their environment and mediate a wide variety of functions. Pilus extension is mediated by an extension ATPase motor, commonly called PilB, in all T4P. Pilus retraction, however, can either occur with the aid of an ATPase motor, or in the…
Ons M’Saad, Michael Shribak, Joerg Bewersdorf
The spatial resolution and contrast sensitivity of the human eye is limited, restricting our ability to directly see subcellular structures. We report a new principle for unaided eye cellular visualization in a method we call Unclearing Microscopy. By expanding cells and tissue >8,000 volumetrically and opaquing their…