21 papers · ranked by Valyu relevance
David Di Giorgio
Neuroscience research has produced many theories and computational neural models of sensory nervous systems. Notwithstanding many different perspectives towards developing intelligent machines, artificial intelligence has ultimately been influenced by neuroscience. Therefore, this paper provides an introduction to…
Silvia Natale, Maria Esteban Masferrer, Senthilkumar Deivasigamani, Cornelius T. Gross
The cerebral cortex is involved in the control of cognition and the processing of learned information and it appears to have a role in the adaptation of behavior in response to unpredictable circumstances. In addition, the cortex may have a role in the regulation of innate responses since rodents, cats or primates with…
Jiawei Zhang
In this paper, we will provide an introduction to the brain structure and function. Brain is an astonishing living organ inside our heads, weighing about 1.5kg, consisting of billions of tiny cells. The brain enables us to sense the world around us (to touch, to smell, to see and to hear, etc.), to think and to respond…
G. Ball, S. Oldham, V. Kyriakopoulou, L. Z. J. Williams + 9 more
The third trimester of human gestation is characterised by rapid increases in brain volume and cortical surface area. A growing catalogue of cells in the prenatal brain has revealed remarkable molecular diversity across cortical areas.^1,2^ Despite this, little is known about how this translates into the patterns of…
Gonçalo Lopes, Joana Nogueira, Joseph J. Paton, Adam R. Kampff
The role of motor cortex in the direct control of movement remains unclear, particularly in non-primate mammals. More than a century of research using stimulation, anatomical and electrophysiological studies has implicated neural activity in this region with all kinds of movement. However, following the removal of…
Luiz Pessoa
What is the relationship between brain and behavior? The answer to this question necessitates characterizing the mapping between structure and function. The aim of this paper is to discuss broad issues surrounding the link between structure and function in the brain that will motivate a network perspective to…
Hossein Haghir, Anika Kuckertz, Ling Zhao, Javad Hami + 1 more
'Nicola Palomero-Gallagher'] Neurotransmitters and their receptors are key molecules in information transfer between neurons, thus enabling inter-areal communication. Therefore, multimodal atlases integrating the brain’s cyto- and receptor architecture constitute crucial tools to understand the relationship between its…
Heejung Jung, Xiaochun Han, Ma Feilong, Jane Han + 6 more
Cortical resources are allocated into systems specialized for processing ecologically relevant features of the world. These features are typically studied in isolation using controlled experimental stimuli, making it difficult to assess the relative importance of different kinds of features that tend to overlap during…
Frédéric Chavane, Diego Contreras
Three rules govern the connectivity between neurons in the thalamus and inhibitory neurons in the visual cortex of rabbits.
Noam Saadon-Grosman, Tsahi Asher, Yonatan Loewenstein
It is well-known that cortical areas specializing in the processing of somatosensory information from different parts of the body are arranged in an orderly manner along the cortex. It is also generally accepted that in the cortex, somatosensory information is initially processed in the primary somatosensory cortex and…
Nicholas G Chehade
Motor cortex (M1) is a crucial brain area for controlling voluntary movements, such as reaching and grasping for a cup of coffee. M1 is organized in a somatotopic manner, such that M1 output driving movement to different parts of the body is organized along the cortical surface. In primates, the arm and hand are…
Matteo Monticelli, Pietro Zeppa, Marco Mammi, Federica Penner + 3 more
'Antonio Melcarne' 'Francesco Zenga' 'Diego Garbossa'] When discussing “mentalization,” we refer to a very special ability that only humans and few species of great apes possess: the ability to think about themselves and to represent in their mind their own mental state, attitudes, and beliefs and those of others. In…
Laurentius Huber, Emily S. Finn, Daniel A. Handwerker, Marlene Bönstrup + 8 more
The human brain coordinates a wide variety of motor activities. On a large scale, the cortical motor system is topographically organized such that neighboring body parts are represented by neighboring brain areas. This homunculus-like somatotopic organization along the central sulcus has been observed using…
Daniel Pouzzner
Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. In more recent studies they have been identified not only in the cerebral cortex and thalamus, but pervasively in the healthy basal ganglia. While correlations with stimuli, behavior, and mental…
Susumu Setogawa, Ryota Kanda, Shuto Tada, Takuya Hikima + 11 more
Characterization of inter-regional interactions in brain is essential for understanding the mechanism relevant to normal brain function and neurological disease. The recently developed flexible micro (μ)-electrocorticography (μECoG) device is one prominent method used to examine large-scale cortical activity across…
William Saban, Shai Gabay
Researchers often attribute higher cognition to the enlargement of cortical regions throughout evolution, reflecting the belief that humans sit at the top of the cognitive pyramid. Implicitly, this approach assumes that the subcortex is of secondary importance for higher-order cognition. While it is now recognized that…
Agnès Gruart, José M. Delgado-García
This review presents a broad perspective of the Neuroscience of our days with special attention to how the brain generates our behaviors, emotions, and mental states. It describes in detail how unconscious and conscious processing of sensorimotor and mental information takes place in our brains. Likewise, classic and…
Peter Coppola
How subjective experience (i.e., consciousness) arises out of objective material processes has been called the hard problem. The neuroscience of consciousness has set out to find the sufficient conditions for consciousness and theoretical and empirical endeavours have placed a particular focus on the cortex and…
Vladimir Shalgunov, Sara Irence Lopes van den Broek, Ida Vang Andersen, Rocío García Vázquez + 12 more
Vladimir Shalgunov 1 , Sara Lopes van den Broek 1 , Ida Vang Andersen 1 , Rocío García Vázquez 1 , Nakul Raval 1 , Mikael Palner 1 , Yuki Mori 1 , Gabriela Schäfer 2 , Hannes Mikula 3 , Natalie Beschorner 1 , Maiken Nedergaard 1 , Stina Syvänen 4 , Matthias Barz 2 , Gitte Moos Knudsen 1 , Umberto Maria Battisti 1 …
Jiwon Lee
Dopamine is a hormone that is released by the adrenal gland and influences motor control and motivation. Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family. The D1 family is known to play a role in motivation and motor control…
Kim-Viktoria Bolik, Jan Hellmann, Simone Maschauer, Eduard Neu + 8 more
Background: The orexin receptor (OXR) plays a role in drug addiction and appears as a tumor marker in colon carcinoma. Subtype-selective OXR PET ligands have not yet been reported. The present work deals with the development of 18F-labeled OXR ligands dervived from selective OX1R antagonist JH112. Methods: Applying…