21 papers · ranked by Valyu relevance
Marco López, Helmuth Hofer, Stefan Kück
A highly accurate method for the determination of the detection efficiency of a silicon single-photon avalanche diode (Si-SPAD) is presented. This method is based on the comparison of the detected count rate of the Si-SPAD compared to the photon rate determined from a calibrated silicon diode using a modified…
Klodian Dhoska, Helmuth Hofer, Beatrice Rodiek, Marco López + 2 more
'Toomas Kübarsepp' 'Stefan Kück'] Background Silicon single-photon avalanche diodes (Si-SPADs) are the most used devices for measuring ultra-weak optical radiant fluxes in many quantum technology fields, such as quantum optics, quantum communication, quantum computing, etc. In all these fields, the detection efficiency…
William C. Chuirazzi, Aaron E. Craft
Digital camera-based neutron imaging systems consisting of a neutron scintillator screen optically coupled to a digital camera are the most common digital neutron imaging system used in the neutron imaging community and are available at any state-of-the-art imaging facility world-wide. Neutron scintillator screens are…
Sumire Sogawa, Kotetsu Sasaki, Akira Kitamura
Protein aggregates are known to disrupt normal cellular functions and homeostasis, serving as key hallmarks of various neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). Automated detection of cytoplasmic, disease-associated aggregates in…
Nolan P. Banish, Summer M. Burdick, Katherine R. Moyer, Z. Daniel Deng
'Z. Daniel Deng'] Portable antennas have become an increasingly common technique for tracking fish marked with passive integrated transponder (PIT) tags. We used logistic regression to evaluate how species, fish length, and physical habitat characteristics influence portable antenna detection efficiency in…
Xiaoqiang Ren, Jiaqi Yan, Yilin Mo
This paper studies binary hypothesis testing based on measurements from a set of sensors, a subset of which can be compromised by an attacker. The measurements from a compromised sensor can be manipulated arbitrarily by the adversary. The asymptotic exponential rate, with which the probability of error goes to zero, is…
Meng Jia, Troy Sorensen, Dorit Hammerling
We propose a generic, modular framework to optimize the placement of continuous monitoring sensors on oil and gas sites aiming to maximize the methane emissions detection efficiency. Our proposed framework substantially expands the problem scale compared to previous related studies and can be adapted for different…
Authors not listed
Colorimetric lateral flow immunoassays (LFIA) have revolutionized point-of-care testing (POCT) methods by providing simple, rapid, accessible, and instrumentation-free detection of infectious diseases. However, conventional LFIAs relying on gold nanospheres (GNPs) can suffer from limited sensitivity due to weak…
Léonard Bezinge, Niklas Tappauf, Daniel A. Richards, Chih-Jen Shih + 1 more
The development of low-cost, disposable electrochemical sensors is an essential step in moving traditionally inaccessible quantitative diagnostic assays towards the point of need. However, a major remaining limitation of current technologies is the reliance on standardized reference electrode materials. Integrating…
Jean‐Luc Margot, Megan G. Li, Pavlo Pinchuk, Nathan Myhrvold + 77 more
'Larry Lesyna' 'Lea E. Alcantara' 'Megan T. Andrakin' 'Jeth Arunseangroj' 'Damien S. Baclet' 'Madison H. Belk' 'Zerxes R. Bhadha' 'Nicholas W. Brandis' 'Robert E. Carey' 'Harrison P. Cassar' 'Sai S. Chava' 'Calvin Chen' 'James L. Chen' 'Kellen T. Cheng' 'Alessia Cimbri' 'Benjamin Cloutier' 'Jordan A. Combitsis' 'Kelly…
Xiaochen Liu, Lihao Wang, Junyuan Zhao, Yinfang Zhu + 2 more
'Fuhua Yang'] A novel microcantilever sensor was batch fabricated for Yersinia detection. The microcantilever surface modification method was optimized by introducing a secondary antibody to increase the number of binding sites. A novel microfluidic platform was designed and fabricated successfully. A 30 μL solution…
Thomas D. Schneider
Unlike the Carnot heat engine efficiency published in 1824, an isothermal efficiency derived from thermodynamics and information theory can be applied to biological systems. The original approach by Pierce and Cutler in 1959 to derive the isothermal efficiency equation came from Shannon’s channel capacity of 1949 and…
Xiaoting Xue, Helena Persson, Lei Ye
Accurate and rapid detection of nucleic acid sequences is of utmost importance in various fields, including disease monitoring, clinical treatment, gene analysis and drug discovery. In this study, we developed a "turn-on" fluorescence biosensor that enables simple and highly efficient detection of nucleic acid…
Ana Díaz-Fernández, Simona Ranallo, Francesco Ricci
Here we report the development of a method for the electrochemical ultrasensitive detection of antibodies that couples the programmability and versatility of DNA-based systems with the sensitivity provided by enzymatic amplification. The platform, termed Enzyme-Linked DNA Displacement (ELIDIS), is based on the use of…
Kiyofumi Miyoshi, Shin’ya Nishida
Human decision behavior entails a graded awareness of its certainty, known as a feeling of confidence. Until now, considerable interest has been paid to behavioral and computational dissociations of decision and confidence, which has raised an urgent need for measurement frameworks that can quantify the efficiency of…
David Luong, Sreeraman Rajan, Bhashyam Balaji
—Quantum two-mode squeezing (QTMS) radars and noise radars detect targets by correlating the received signal with an internally stored recording. A covariance matrix can be calculated between the two which, in theory, is a function of a single correlation coefficient. This coefficient can be used to decide whether a…
G.F. Hatke, M. Montanari, S. Appadwedula, Michael Wentz + 4 more
The process of contact tracing to reduce the spread of highly infectious and life-threatening diseases has traditionally been a primarily manual process managed by public health entities. This process becomes challenged when faced with a pandemic of the proportions of SARS-CoV2. Digital contact tracing has been…
Vijaya Yajnanarayana, Satyam Dwivedi, Peter Händel
—Optimal detection of ultra wideband (UWB) pulses in a UWB transceiver employing multiple detector types is proposed and analyzed in this paper. To enable the transceiver to be used for multiple applications, the designers have different types of detectors such as energy detector, amplitude detector, etc., built in to…
Pascal Mamassian, Vincent de Gardelle
Over the last decade, different approaches have been proposed to interpret confidence rating judgments obtained after perceptual decisions. One very popular approach is to compute meta-d’ which is a global measure of the sensibility to discriminate the confidence rating distributions for correct and incorrect…
David Luong, Bhashyam Balaji, Sreeraman Rajan
—We derive a detector that optimizes the target detection performance of any single-input single-output noise radar satisfying the following properties: it transmits Gaussian noise, it retains an internal reference signal for matched filtering, all external noise is additive white Gaussian noise, and all signals are…
Authors not listed
Lateral flow assays (LFAs) are point-of-care devices known for their affordability, speed, and simplicity. However, their sensitivity is often limited due to the need for fast associative rates between assay components. This work presents a strategy towards reducing the demand for fast test line associative kinetics…