25 papers · ranked by Valyu relevance
Yongyi Zhao, Ankit Raghuram, Fay Wang, Stephen Hyunkeol Kim + 3 more
'Andreas Hielscher' 'Jacob T. Robinson' 'Ashok Veeraraghavan'] Title: Abstract. Significance Imaging through scattering media is critical in many biomedical imaging applications, such as breast tumor detection and functional neuroimaging. Time-of-flight diffuse optical tomography (ToF-DOT) is one of the most promising…
Hao Yang Wu, Andrew Filer, Iain Styles, Hamid Dehghani
A multi-wavelength diffuse optical tomography (DOT) system has been developed to directly extract physiological information, such as total haemoglobin concentration, from tissue in human hand joints. Novel methods for 3D surface imaging and spectrally constrained image reconstruction are introduced and their potential…
Xiaohua Feng, Liang Gao
Diffuse optical tomography (DOT) is well known to be ill-posed and suffers from a poor resolution. While time domain DOT can bolster the resolution by time-gating to extract weakly scattering photons, it is often confronted by an inferior signal to noise ratio and a low measurement density. This is particularly…
Robin Dale, Biao Zheng, Felipe Orihuela-Espina, Nicholas Ross + 3 more
'Thomas D. O’Sullivan' 'Scott Howard' 'Hamid Dehghani'] Title: Abstract. Significance Frequency-domain diffuse optical tomography (FD-DOT) could enhance clinical breast tumor characterization. However, conventional diffuse optical tomography (DOT) image reconstruction algorithms require case-by-case expert tuning and…
Manabu Machida, Keita Osada, Keiichiro Kagawa
The stripe illumination lies between the illumination in the spatialfrequency domain and the point illumination. Although the stripe illumination has a periodic structure as the illumination in the spatial-frequency domain, light from the stripe illumination can reach deep regions in biological tissue since it can be…
Xiaofeng Zhang
Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence, and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument…
Philip Gemmell, Martin Bishop
Catheter ablation in patients suffering from chronic arrhythmias requires detailed knowledge of the underlying cardiac anatomy; such real-time, high resolution mapping is currently unavailable in a clinical setting. We present here preliminary work towards a novel optical strategy based on diffuse optical reflectance…
Anssi H Manninen, Meghdoot Mozumder, Tanja Tarvainen, Andreas Hauptmann
'Andreas Hauptmann'] Diffuse optical tomography (DOT) is a severely ill-posed nonlinear inverse problem that seeks to estimate optical parameters from boundary measurements. In the Bayesian framework, the ill-posedness is diminished by incorporating a priori information of the optical parameters via the prior…
Meghdoot Mozumder, Jarkko Leskinen, Tanja Tarvainen
In this work, feasibility of nanosecond scale light pulses as sources for time-domain DOT is studied. Nanosecond sources enable using relatively robust measurement setups with standard analog-to-digital converter waveform digitizers, such as digital oscilloscopes. However, this type of systems have some properties…
Joseph P. Angelo, Sez-Jade Chen, Marien Ochoa, Ulas Sunar + 2 more
'Sylvain Gioux' 'Xavier Intes'] Title: Abstract. Diffuse optical imaging probes deep living tissue enabling structural, functional, metabolic, and molecular imaging. Recently, due to the availability of spatial light modulators, wide-field quantitative diffuse optical techniques have been implemented, which benefit…
Zhi-Yuan Li, Chunlong Sun
In this work, an inverse problem on the determination of multiple coefficients arising from the time-domain diffuse optical tomography with fluorescence (DOT-FDOT) is investigated. We simultaneously recover the distribution of background absorption coefficient, photon diffusion coefficient as well as the fluorescence…
Mingwei He, Sujit K. Sahoo, Chengyuan Xiao, Cuong Dang
Various imaging techniques have significantly enhanced our ability to visualize objects embedded within complex media such as biological tissues, fog, atmosphere, or various turbid media. Optical imaging, in particular, offers multiple advantages, including non-invasive capabilities, absence of ionizing radiation, and…
Yanyu Zhao, Bowen Song, Ming Wang, Yang Zhao + 1 more
The ability to quantify optical properties (i.e., absorption and scattering) of strongly turbid media has major implications on the characterization of biological tissues, fluid fields, and many others. However, there are few methods that can provide wide-field quantification of optical properties, and none is able to…
Yuyao Pan, Kui Ren, Shanyin Tong
photoacoustic and diffuse optical imaging Authors: ['Yuyao Pan' 'Kui Ren' 'Shanyin Tong'] This paper studies inverse problems in quantitative photoacoustic tomography with additional optical current data supplemented from diffuse optical tomography. We propose a three-stage image reconstruction method for the…
Daniele Ancora
| Abstract 9 | | --- | | Introduction 11 | | Chapter I THEORY OF LIGHT DIFFUSION IN BIOLOGICAL TISSUES 15 | | I.1 Light Diffusion in Biological Tissues 17 | | I.2 Radiative Transfer Equation 23 | | I.2.1 DERIVATION OF THE RADIATIVE TRANSFER EQUATION 26 | | I.2.2 DIFFUSION EQUATION 29 | | I.3 Monte Carlo Photon…
Leo Puyó, Clara Pfäffle, Hendrik Spahr, Jonas Franke + 3 more
'Daniel Bublitz' 'Dierck Hillmann' 'Gereon Hüttmann'] Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing diffuse illumination of…
Hao Yang, Shixie Jiang, Huabei Jiang
Early detection of Alzheimer’s disease (AD) remains limited by the inability of current imaging biomarkers to capture dynamic tissue changes preceding overt neurodegeneration. Conventional approaches primarily reflect molecular burden or structural atrophy and incompletely characterize the intermediate…
Giulia Giubertoni, Marina Gomes Rachid, Carolyn Moll, Michiel Hilbers + 2 more
Based on concepts from nuclear magnetic resonance, we have developed UV/Vis Diffusion-Ordered Spectroscopy, which simultaneously probes the size and the electronic spectrum of molecules and particles. We use simple flow technology to create a step-function concentration profile inside an optical sample cell, and by…
Elzbieta Stepula, Anders R. Walther, Dev Mehrotra, Magnus Jensen + 6 more
The ability to image tissues in three-dimensions (3-D) with label-free molecular contrast at mesoscale would be a valuable capability in biology and biomedicine. Here, we introduce Raman spectral projection tomography (RSPT) for live volumetric molecular imaging of tissues with sub-millimeter spatial resolution. We…
Sarthak Patnaik
We know that the diffusion is defined as the movement of molecules under a potential gradient. It is characterized by the diffusion coefficient. Diffusion coefficient determination can be done via various techniques, but in this paper, we have had a broad look at interferometry based optical methods for diffusion…
Connor Darling, Samuel P.X. Davis, Sunil Kumar, Paul M.W. French + 1 more
We present a single-shot adaptation of Optical Projection Tomography (OPT) for high-speed volumetric snapshot imaging of dynamic mesoscopic samples. Conventional OPT has been applied to in vivo imaging of animal models such as D. rerio but the sequential acquisition of projection images required for volumetric…
Axel Ekman, Venera Weinhardt, Jian-Hua Chen, Gerry McDermott + 2 more
In this manuscript, we introduce a linear approximation of the forward model of soft x-ray tomography (SXT), such that the reconstruction is solvable by standard iterative schemes. This linear model takes into account the three-dimensional point spread function (PSF) of the optical system, which consequently enhances…
Kejian Qu, Hrishikesh Bale, Zachary Riedel, Junehu Park + 3 more
Single crystals of rhombohedral KBiS2 were synthesized for the first time, and the structure, growth habit and properties of this layered semiconductor are presented. The single crystals form from a reactive K2S5 salt flux and are still embedded in the residual flux, without removal from the reaction vessel throughout…
Authors not listed
nDTomo is a Python-based software suite for the simulation, reconstruction and analysis of X-ray chemical imaging and computed tomography data. It provides a collection of Python function-based tools designed for accessibility and education as well as a graphical user interface (GUI). Prioritising transparency and ease…
Ashley Fidler, Yen-Cheng Lin, James Gaynor, William McCurdy + 3 more
Nonlinear spectroscopies can disentangle spectra that are congested due to inhomogeneous broadening. In conjunction with theoretical calculations, attosecond extreme ultraviolet (XUV) four-wave mixing (FWM) spectroscopy is utilized here to probe the dynamics of autoionizing, inner valence excited Rydberg states of the…