24 papers · ranked by Valyu relevance
Lydiane Hirschler, Nico Sollmann, Bárbara Schmitz‐Abecassis, Joana Pinto + 37 more
'Joana Pinto' 'Fatemehsadat Arzanforoosh' 'Frederik Barkhof' 'Thomas Booth' 'Marta Calvo‐Imirizaldu' 'Guilherme Cassia' 'Marek Chmelik' 'Patricia Clement' 'Ece Ercan' 'Maria A. Fernández‐Seara' 'Julia Furtner' 'Elies Fuster‐Garcia' 'Matthew Grech‐Sollars' 'Nazmiye Tugay Guven' 'Gokce Hale Hatay' 'Golestan Karami' 'Vera…
Otto M. Henriksen, María del Mar Álvarez-Torres, Patricia Figueiredo, Gilbert Hangel + 7 more
'Gilbert Hangel' 'Vera C. Keil' 'Ruben E. Nechifor' 'Frank Riemer' 'Kathleen M. Schmainda' 'Esther A. H. Warnert' 'Evita C. Wiegers' 'Thomas C. Booth'] Objective Summarize evidence for use of advanced MRI techniques as monitoring biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods…
Alexandru V. Avram, Kadharbatcha S. Saleem, Peter J. Basser
Diffusion MRI studies with resolutions of a few hundred micrometers have consistently shown that in the cortex water diffusion occurs preferentially along radial and tangential orientations with respect to the cortical surface, in agreement with histology. These dominant orientations do not change significantly even if…
Anna Caroli
Since its discovery in the 1980s [1], diffusion-weighted MRI (DWI), a non-invasive imaging method that does not require any tracer injection, has experienced exponential growth, becoming a pillar of modern clinical imaging. DWI enables the investigation of tissue microstructure. In fact, during their random…
Ileana Jelescu, Francesco Grussu, Andrada Ianuş, Brian Benjamin Hansen + 53 more
'Brian Benjamin Hansen' 'Rachel Barrett' 'Manisha Aggarwal' 'Stijn Michielse' 'Fatima A. Nasrallah' 'Warda Syeda' 'Nian Wang' 'Jelle Veraart' 'Alard Roebroeck' 'Andrew F. Bagdasarian' 'Cornelius Eichner' 'Farshid Sepehrband' 'Jan Zimmermann' 'Lucas Soustelle' 'Christien Bowman' 'Benjamin C. Tendler' 'Andreea Hertanu'…
Pamela Wochner, Torben Schneider, Jason Stockmann, Jack Lee + 2 more
'Ralph Sinkus' 'Pew-Thian Yap'] Diffusion MRI classically uses gradient fields that vary linearly in space to encode the diffusion of water molecules in the signal magnitude by tempering its intensity. In spin ensembles, a presumably equal number of particles move in positive and negative direction, resulting in…
Ramona Cirstian, Natalie J. Forde, Jesper L.R. Andersson, Stamatios N. Sotiropoulos + 2 more
Diffusion MRI is a neuroimaging modality used to evaluate brain structure at a microscopic level and can be exploited to map white matter fibre bundles and microstructure in the brain. One common issue is the presence of artefacts, such as acquisition artefacts, physiological artefacts, distortions or image…
Alexandru V. Avram, Kadharbatcha S. Saleem, Peter J. Basser
High-resolution imaging studies have consistently shown that in cortical tissue water diffuses preferentially along radial and tangential orientations with respect to the cortical surface, in agreement with histology. These dominant orientations do not change significantly even if the relative contributions from…
Anna Falk Delgado
Glial tumors and especially glioblastoma present a major challenge in neuro-oncology due to their infiltrative growth, resistance to therapy, and poor overall survival-despite aggressive treatments such as maximal safe resection and chemoradiotherapy. These tumors typically manifest through neurological symptoms such…
Coelho, Santiago, Lemberskiy, Gregory + 12 more
This work was partially supported by National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering; Grant/Award Number: P41-EB017183, R01-EB027075, and K99-EB036080, and National Institute of Neurological Disorders and Stroke; Grant/Award Number: R01-NS088040, and Office of the Director and…
Rafael Neto Henriques, Richard N. Henson, Cam‐CAN, Marta Correia
R.N.H. was supported by the Scientific Employment Stimulus 4th Edition from Fundação para a Ciência e Tecnologia, Portugal, ref 2021.02777.CEECIND. R.H. was supported by MRC programme grant SUAG/046 G101400. Cam-CAN was supported by the Biotechnology and Biological Sciences Research Council under grant BB/H008217/1.…
Jessica T.E. Johnson, M. Okan Irfanoglu, Eppu Manninen, Thomas J. Ross + 5 more
Diffusion MRI with free gradient waveforms, combined with simultaneous relaxation encoding, referred to as multidimensional MRI (MD-MRI), offers microstructural specificity in complex biological tissue. This approach delivers intravoxel information about the microstructure, local chemical composition, and importantly…
Haykel Snoussi, Benoît Combès, Olivier Commowick, Élise Bannier + 4 more
'Anne Kerbrat' 'Julien Cohen‐Adad' 'Christian Barillot' 'Emmanuel Caruyer'] Abstract. In Multiple Sclerosis (MS), there is a large discrepancy between the clinical observations and how the pathology is exhibited on brain images, this is known as the clinical-radiological paradox (CRP). One of the hypotheses is that the…
Maxime Yon, Omar Narvaez, Daniel Topgaard, Alejandra Sierra
Massively Multidimensional Diffusion MRI combines tensor-valued encoding, oscillating gradients, and diffusion-relaxation correlation to provide multicomponent sub-voxel parameters depicting the tissue microstructure. This method was successfully implemented ex vivo in micro-imaging systems and in clinical conditions…
Marc Azagra, David Gomez-Cabeza, Alejandro Portela, Gergo Matajsz + 3 more
To foster the efficient development of 3D cell culture models, we developed a strategy to assess the liquid flow perfusion through biocompatible scaffolds. Biocompatible scaffolds play a crucial role in creating 3D in vitro models for precision medicine. Therefore, it is imperative to thoroughly characterise the…
Stephanie Crater, Surendra Maharjan, Yi Qi, Qi Zhao + 4 more
Diffusion magnetic resonance imaging has been widely used in both clinical and preclinical studies to characterize tissue microstructure and structural connectivity. The diffusion MRI protocol for the Human Connectome Project (HCP) has been developed and optimized to obtain high-quality, high-resolution diffusion MRI…
Maxime Yon, Omar Narvaez, Daniel Topgaard, Alejandra Sierra
Massively multidimensional diffusion magnetic resonance imaging combines tensor-valued encoding, oscillating gradients, and diffusion-relaxation correlation to provide multicomponent subvoxel parameters depicting some tissue microstructural features. This method was successfully implemented ex vivo in microimaging…
Kanza Awais, Žiga Snoj, Erika Cvetko, Igor Serša + 3 more
'Federico Bruno' 'Ayesha Jameel'] The magnetic resonance Diffusion Tensor Imaging (DTI) is a powerful extension of Diffusion Weighted Imaging (DWI) utilizing multiple bipolar gradients, allowing for the evaluation of the microstructural environment of the highly anisotropic tissues. DTI was predominantly used for the…
Eloïse Mougel, Julien Valette, Marco Palombo
In this work we use diffusion-weighted MR spectroscopy (dMRS) of water and metabolite as a function of diffusion time in vivo in mouse gray matter to shed light on: i) which of these concomitant mechanisms (structural disorder, restriction and exchange) dominates the MR measurements and ii) with which specific…
Zejun Wu, Jiechao Wang, Zunquan Chen, Qinqin Yang + 3 more
'Zhong Chen' 'Congbo Cai'] Abstract. Objective: Most deep neural network-based diffusion tensor imaging methods require the diffusion gradients' number and directions in the data to be reconstructed to match those in the training data. This work aims to develop and evaluate a novel dynamic-convolution-based method…
Arthur P C Spencer, Jasmine Nguyen-Duc, Inès de Riedmatten, Filip Szczepankiewicz + 1 more
Functional MRI (fMRI) using the blood-oxygen level dependent (BOLD) signal provides valuable insight into grey matter activity. However, uncertainty surrounds the white matter BOLD signal. Apparent diffusion coefficient (ADC) offers an alternative fMRI contrast sensitive to transient cellular deformations during neural…
Kadharbatcha S Saleem, Alexandru V Avram, Cecil Chern-Chyi Yen, Kulam Najmudeen Magdoom + 2 more
Subcortical nuclei and other deep brain structures play essential roles in regulating the central and peripheral nervous systems. However, many of these nuclei and their subregions are challenging to identify and delineate in conventional MRI due to their small size, hidden location, and often subtle contrasts compared…
Authors not listed
When producing plant-protein-based meat analogues via high moisture extrusion (HME), the structure of extrudates is determined by complex interactions between ingredient composition and processing conditions. To facilitate consumers in their transition towards a diet higher in plant-based proteins, the food industry…
Authors not listed
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and widespread neurovascular disturbances. Traditional fMRI provides valuable spatial maps of blood-oxygen-level-dependent (BOLD) changes but often lacks the capacity to quantify the interplay of cerebral blood flow…