23 papers · ranked by Valyu relevance
Marc Lim, Vishnu Dharmaraj, Boying Gong, Ting Xu
Understanding the complex interplay of factors affecting nanoparticle accumulation in solid tumors is a challenge that must be surmounted to develop effective cancer nanomedicine. The tumor microenvironment is unique in comparison to healthy tissue, possessing elevated interstitial pressure that limits convective…
Fabio Tatti, Marco Petrangeli Papini, Massimo Raboni, Paolo Viotti
In this study, the long-term tailing derived from the storage process of contaminants in low-permeability zones is investigated. The release from these areas in the groundwater can be considered a long-term source that often undermines remediation efforts. An Image Analysis technique is used to analyze the process and…
Christophe Tournassat, Carl I. Steefel, Patricia M. Fox, Ruth M. Tinnacher
'Ruth M. Tinnacher'] The reactive transport code CrunchClay was used to derive effective diffusion coefficients (D*e), clay porosities (ε), and adsorption distribution coefficients (K**D) from through-diffusion data while considering accurately the influence of unavoidable experimental biases on the estimation of these…
B. U. Felderhof
It is shown that in isothermal isobaric diffusion of a binary fluid mixture the mean volume velocity vanishes in the linear regime, independent of the equation of state. The partial specific volumes of the two components are uniform and constant in the process of mutual diffusion. The properties lead to a simple…
Gregory L. Eyink, Amir Homayoun Jafari
We discuss application of methods from the Kraichnan model of turbulent advection to the study of non-equilibrium concentration fluctuations arising during diffusion in liquid mixtures at high Schmidt numbers. This approach treats nonlinear advection of concentration fluctuations exactly, without linearization.…
J. A. del Río, S. Whitaker
In this study the laws of mechanics for multi-component systems are used to develop a theory for the diffusion of ions in the presence of an electrostatic field. The analysis begins with the governing equation for the species velocity and it leads to the governing equation for the species diffusion velocity.…
Francisca Guzmán-Lastra, Hartmut Löwen, Arnold J. T. M. Mathijssen
Biological activity is often highly concentrated on surfaces, across the scales from molecular motors and ciliary arrays to sessile and motile organisms. These ‘active carpets’ locally inject energy into their surrounding fluid. Whereas Fick’s laws of diffusion are established near equilibrium, it is unclear how to…
Aleksandar Donev, Thomas G. Fai, Eric Vanden‐Eijnden
A model for diffusion in liquids that couples the dynamics of tracer particles to a fluctuating Stokes equation for the fluid is investigated in the limit of large Schmidt number. In this limit, the concentration of tracers is shown to satisfy a closed-form stochastic advection-diffusion equation that is used to…
Iman Abdoli, Hidde Derk Vuijk, Jens‐Uwe Sommer, J. M. Brader + 1 more
'Abhinav Sharma'] The Fokker-Planck equation provides complete statistical description of a particle undergoing random motion in a solvent. In the presence of Lorentz force due to an external magnetic field, the Fokker-Planck equation picks up a tensorial coefficient, which reflects the anisotropy of the particle's…
Authors not listed
Predicting how often molecules collide in dilute solution remains a long-standing challenge often with several orders of magnitude difference between theoretical values and experimental values also among different experimental values. Traditional frameworks from Smoluchowski and Langmuir rely on the formation of stable…
Jixin Chen
Predicting the reaction kinetics, that is, how fast a reaction can happen in a solution, is essential information for many processes, such as industrial chemical manufacturing, refining, synthesis and separation of petroleum products, environmental processes in air and water, biological reactions in cells, biosensing…
Rena Elkin, Saad Nadeem, Eve LoCastro, Ramesh Paudyal + 5 more
Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) provides a quantitative measure of pharmacokinetic (PK) parameters in body tissues; it entails collection of a series of T1-weighted images following the administration of a paramagnetic contrast agent (CA). Current state-of-the-art models for estimating…
Hidde Derk Vuijk, Jens‐Uwe Sommer, Holger Merlitz, J. M. Brader + 1 more
'Abhinav Sharma'] We consider the nonequilibrium dynamics of a charged active Brownian particle in the presence of a space dependent magnetic field. It has recently been shown that the Lorentz force induces a particle flux perpendicular to density gradients, thus preventing a diffusive description of the dynamics.…
Iman Abdoli, Hidde Derk Vuijk, René Wittmann, Jens‐Uwe Sommer + 2 more
'J. M. Brader' 'Abhinav Sharma'] In systems with overdamped dynamics, the Lorentz force reduces the diffusivity of a Brownian particle in the plane perpendicular to the magnetic field. The anisotropy in diffusion implies that the Fokker-Planck equation for the probabiliy distribution of the particle acquires a…
Jixin Chen
Diffusive adsorption/association is a fundamental step in almost all chemical reactions in diluted solutions, such as organic synthesis, polymerization, self-assembly, biomolecular interactions, electrode dynamics, catalysis, chromatography, air and water environmental dynamics, and social and market dynamics. However…
Achuthan Raja Venkatesh, Kathy H Le, David M Weld, Onn Brandman + 2 more
'Pierre Sens' 'Aleksandra M Walczak'] While inhomogeneous diffusivity has been identified as a ubiquitous feature of the cellular interior, its implications for particle mobility and concentration at different length scales remain largely unexplored. In this work, we use agent-based simulations of diffusion to…
Srijana Pandey, Dinesh Gautam, Jixin Chen
Many interactions between small molecules and particles occur in solutions. They are surrounded by other molecules that do not react, for example, biological processes in water, chemical reactions in gas or liquid solutions, and environmental reactions in air and water. Predicting the rate of such interactions involves…
Felix J. Meigel, Thomas Darwent, Leonie Bastin, Lucas Goehring + 1 more
'Karen Alim'] Understanding and controlling transport through complex media is central for a plethora of processes ranging from technical to biological applications. Yet, the effect of micro-scale manipulations on macroscopic transport dynamics still poses conceptual conundrums. Here, we demonstrate the predictive…
Steven J. Moran, Ryan Oglietti, Kathleen C. Smith, Jed C. Macosko + 2 more
Viral and cellular particles too large to freely diffuse have two different types of mobility in the eukaryotic cell cytoplasm: directed motion mediated by motor proteins moving along cytoskeletal elements with the particle as its load, and motion in random directions mediated by motor proteins interconnecting…
Debabrata Dey, Shir Marciano, Gideon Schreiber
A cell is a densely packed conglomerate of macromolecules, where diffusion is essential for their function. The crowded conditions may affect diffusion both through hard (occluded space) and soft (weak, non-specific) interactions. Multiple-methods have been developed to measure diffusion rates at physiological protein…
Sina Jazani, Ioannis Sgouralis, Omer M. Shafraz, Sanjeevi Sivasankar + 1 more
Fluorescence correlation spectroscopy (FCS), is a flexible and widely used tool routinely exploited in vivo. While FCS provides estimates of dynamical quantities, such as diffusion coefficients, it demands high molecular concentrations, high signal to noise ratio and long time traces typically in the minute range. This…
Jixin Chen
Predicting the reaction kinetics, that is, how fast a reaction can happen in a solution, is essential information for many processes, such as industrial chemical manufacturing, refining, synthesis and separation of petroleum products, environmental processes in air and water, biological reactions in cells, biosensing…
Jixin Chen
Predicting the reaction kinetics, that is, how fast a reaction can happen in a solution, is essential information for many processes, such as industrial chemical manufacturing, refining, synthesis and separation of petroleum products, environmental processes in air and water, biological reactions in cells, biosensing…