23 papers · ranked by Valyu relevance
Zhengwu Sun, Payel Sen, Jules Hamers, Thomas Seidel + 3 more
'Andreas Dendorfer' 'Petra Kameritsch' 'Stefania Romeo'] The cultivation of excitable cells typically profits from continuous electrical stimulation, but electrochemical consequences are mostly harmful and must be minimized. The properties of the electrode materials and stimulation impulses are key. Here, we developed…
Authors not listed
The nerve cell, or neuron, is the key player in the activity of the nervous system. It conveys information both electrically and chemically. Within the neuron itself, information is passed along through the movement of an electrical charge (i.e., impulse). The neuron has three main components: (1) the dendrites, thin…
Benjamin Drukarch, Micha M. M. Wilhelmus
Ever since the work of Edgar Adrian, the neuronal action potential has been considered as an electric signal, modeled and interpreted using concepts and theories lent from electronic engineering. Accordingly, the electric action potential, as the prime manifestation of neuronal excitability, serving processing and…
Michel Peyrard
In the last fifteen years a debate emerged about the validity of the famous Hodgkin-Huxley model for nerve impulse. Mechanical models have been proposed. This note reviews the experimental properties of the nerve impulse and discusses the proposed alternatives. The experimental data, which rule out some of the…
M. Pekker, M.N. Shneider
A theoretical model of electrical synapses is proposed, in which connexons play the role of “nails” that hold unmyelinated areas of neurons at a distance of about 3.5 nm, and the electrical connection between them is provided by charging the membrane of an inactive neuron with currents generated in the intercellular…
William Winlow, Andrew S. Johnson
> "The great sins of the world take place in the brain, but it is in the brain that everything takes place.... it is in the brain that the poppy is red, that the apple is odorous, that the skylark sings" (Wilde, 1891 105) and the soliton and the action potential are the primary elements underlying sentience 5 – they…
Emanuele Formento, Edoardo D’Anna, Sandra Gribi, Stéphanie P. Lacour + 1 more
Electrical stimulation is an effective method to communicate with the nervous system. Here, we demonstrate that current stimulation paradigms fail to reproduce the stochastic and asynchronous properties of natural patterns of neural activity, and introduce a novel biomimetic stimulation (BioS) strategy that overcomes…
Hui Ye, Jenna Hendee, Joyce Ruan, Alena Zhirova + 2 more
'Maria Dima'] Neuromodulation with electromagnetic stimulation is widely used for the control of abnormal neural activity, and has been proven to be a valuable alternative to pharmacological tools for the treatment of many neurological diseases. Tremendous efforts have been focused on the design of the stimulation…
Silvia Ronchi, Michele Fiscella, Camilla Marchetti, Vijay Viswam + 3 more
'Jan Müller' 'Urs Frey' 'Andreas Hierlemann'] Non-invasive electrical stimulation can be used to study and control neural activity in the brain or to alleviate somatosensory dysfunctions. One intriguing prospect is to precisely stimulate individual targeted neurons. Here, we investigated single-neuron current and…
Tuan Pham, Julie S. Haas
As information about the world traverses the brain, the signals exchanged between neurons are passed and modulated by synapses, or specialized contacts between neurons. While neurotransmitter-based synapses tend to be either relay excitatory or inhibitory pulses of influence on the postsynaptic neuron, electrical…
Alfredo González‐Pérez, Rima Budvytytė, Lars D. Mosgaard, Søren Nissen + 1 more
'Søren Nissen' 'Thomas Heimburg'] The collisions of two simultaneously generated impulses in the giant axons of both earthworms and lobster propagating in orthodromic and antidromic direction were investigated. The experiments have been performed on the extracted ventral cords of Lumbricus terrestris and the abdominal…
Andrew Adamatzky, Antoni Gandia
Fungi exhibit action-potential like spiking activity. Up to date most electrical activity of oyster fungi has been characterised in sufficient detail. It remains unclear if there are any patterns of electrical activity specific only for a certain set of species or if all fungi share the same ‘language’ of electrical…
Rita Matta, Davide Reato, Alberto Lombardini, David Moreau + 1 more
Electrical stimulation is a powerful tool for investigating and modulating brain activity, as well as for treating neurological disorders. However, understanding the precise effects of electrical stimulation on neural activity has been hindered by limitations in recording neuronal responses near the stimulating…
Jiahui Wang, Hao Wang, Xin Yuan Thow, Nitish V. Thakor + 1 more
'Chengkuo Lee'] Electrical stimulation is an artificial way to initiate action potentials in excitable neural tissues. We conducted pure physical reasoning of electrical stimulation influence on transmembrane ion distribution and found that neuron excitability can be affected to either increase (stronger force) or…
Nicholas J. Michelson, James R. Eles, Alberto L. Vazquez, Kip A Ludwig + 1 more
Electrical stimulation of the brain has become a mainstay of fundamental neuroscience research and an increasingly prevalent clinical therapy. Despite decades of use in basic neuroscience research and the growing prevalence of neuromodulation therapies, gaps in knowledge regarding activation or inactivation of neural…
Erich W. Schmid, Wolfgang Fink
2Visual and Autonomous Exploration Systems Research Laboratory, Division of Physics, Mathematics and Astronomy, California Institute of Technology, Pasadena, CA 91125, USA 3Visual and Autonomous Exploration Systems Research Laboratory, Departments of Electrical & Computer Engineering, Biomedical Engineering, Systems &…
Jiahui Wang, Hao Wang, Xin Yuan Thow, Nitish V. Thakor
The existing Finite Element Modeling (FEM) fails to model the real electric field that activates a neuron, because the computation capability is insufficient to represent the neural tissue down to an atom-level. Thus, to reveal the real electrode-tissue interactions, we adopt the idea of using a circuit to simulate…
Sasi S. Madugula, Lauren E. Grosberg, Nishal P. Shah, Alexandra Kling + 5 more
High-fidelity sensory neural implants must be calibrated to precisely activate specific cells via extracellular stimulation. However, collecting and analyzing the required electrical stimulation data may be difficult in the clinic. A potential solution is to infer stimulation sensitivity from intrinsic electrical…
Andrew S. Johnson, William Winlow
Conventionally it is assumed that the nerve impulse is an electrical process based upon the observation that electrical stimuli produce an action potential as defined by Hodgkin Huxley (1952) (HH). Consequently, investigations into the computation of nerve impulses have almost universally been directed to electrically…
Jesse C. Dean, Joanna M. Clair-Auger, Olle Lagerquist, David F. Collins
'David F. Collins'] Motoneurons receive a barrage of inputs from descending and reflex pathways. Much of our understanding about how these inputs are transformed into motor output in humans has come from recordings of single motor units during voluntary contractions. This approach, however, is limited because the input…
Andrew S Johnson, William Winlow
Conventionally it is assumed that the nerve impulse is an electrical process based upon the observation that electrical stimuli produce an action potential as defined by Hodgkin Huxley (1952) (HH). Consequently, investigations into the computation of nerve impulses have almost universally been directed to electrically…
Authors not listed
As demand rises for scalable and sustainable energy storage, fast and low-cost diagnostics capable of identifying cell-to-cell variations are urgently needed, particularly for factory-produced sorting and second-life assessment. Electrochemical impedance spectroscopy (EIS) is widely used but remains slow, expensive and…
Andie Robinsons, Craig McBeth, Ruman Rahman, Richard Hague + 1 more
The field of bioelectronics is developing exponentially. There is now a drive to interface electronics with biology for the development of new technologies to improve our understanding of electrical forces in biology. This builds on our recently published work in which we show wireless electrochemistry could be used to…