20 papers · ranked by Valyu relevance
Boucheron Stephane, Élisabeth Gassiat, Mesrob I. Ohannessian
—In this paper, we study the problem of lossless universal source coding for stationary memoryless sources on countably infinite alphabets. This task is generally not achievable without restricting the class of sources over which universality is desired. Building on our prior work, we propose natural families of…
Jayadev Acharya, Ashkan Jafarpour, Alon Orlitsky, Ananda Theertha Suresh
'Ananda Theertha Suresh'] The Poisson-sampling technique eliminates dependencies among symbol appearances in a random sequence. It has been used to simplify the analysis and strengthen the performance guarantees of randomized algorithms. Applying this method to universal compression, we relate the redundancies of…
Anna Ben-Hamou, Stéphane Boucheron, Élisabeth Gassiat
Adaptive coding faces the following problem: given a collection of source classes such that each class in the collection has non-trivial minimax redundancy rate, can we design a single code which is asymptotically minimax over each class in the collection? In particular, adaptive coding makes sense when there is no…
Silvana Bazzoni, Giovanna Le Gros
Given a 1-tilting cotorsion pair over a commutative ring, we characterise the rings over which the 1-tilting class is an enveloping class. To do so, we consider the faithful finitely generated Gabriel topology G associated to the 1-tilting class T over a commutative ring as illustrated by Hrbek. We prove that a…
Elizabeth A. Ellithorpe, Gaspard Duchêne, Steven W. Stahler
We present a quantitative, empirically based argument that at least some Class I sources are lowmass, pre-main-sequence stars surrounded by spatially extended envelopes of dusty gas. The source luminosity arises principally from stellar gravitational contraction, as in optically visible pre-mainsequence stars that lack…
Dylan A. Frabutt, Yong-Hui Zheng, Jaquelin Dudley
Enveloped viruses represent a significant category of pathogens that cause serious diseases in animals. These viruses express envelope glycoproteins that are singularly important during the infection of host cells by mediating fusion between the viral envelope and host cell membranes. Despite low homology at protein…
Courtney E Garry, Robert F Garry
The Bunyaviridae family of enveloped RNA viruses includes five genuses, orthobunyaviruses, hantaviruses, phleboviruses, nairoviruses and tospoviruses. It has not been determined which Bunyavirus protein mediates virion:cell membrane fusion. Class II viral fusion proteins (beta-penetrenes), encoded by members of the…
Yongtao Xu, Shui Yu, Jian-Wei Zou, Guixiang Hu + 5 more
'Noorsaadah A. B. D. Rahman' 'Rozana Binti Othman' 'Xia Tao' 'Meilan Huang' 'Massimiliano Galdiero'] The peptides derived from envelope proteins have been shown to inhibit the protein-protein interactions in the virus membrane fusion process and thus have a great potential to be developed into effective antiviral…
Courtney E Garry, Robert F Garry
Background Members of the Baculoviridae encode two types of proteins that mediate virus:cell membrane fusion and penetration into the host cell. Alignments of primary amino acid sequences indicate that baculovirus fusion proteins of group I nucleopolyhedroviruses (NPV) form the GP64 superfamily. The structure of these…
Michael G Metzen, Maurice J Chacron
Natural sensory stimuli are characterized by time varying moments such as mean (first-order) and variance (second-order). While psychophysical studies have shown that second order attributes (the envelope) are critical for perception, how they are encoded in the brain remains largely unknown. Here we focused on…
Camille Lozada, Thomas M. A. Barlow, Simon Gonzalez, Nadège Lubin-Germain + 1 more
'Nadège Lubin-Germain' 'Steven Ballet'] Membrane fusion events allow enveloped viruses to enter and infect cells. The study of these processes has led to the identification of a number of proteins that mediate this process. These proteins are classified according to their structure, which vary according to the viral…
Moshe Y. Flugelman, Robert M. Glueck, Doron Aronson, Avinoam Shiran
Purpose: Active learning improves knowledge acquisition and provides medical students with learning habits that become an integral part of their behavior. As an integral element of our institution’s transition from a lecture hall teaching culture to active learning, the current project, conducted with fourth year…
Chetan S Poojari, Tobias Bommer, Jochen S Hub
Viral infection requires stable binding of viral fusion proteins to host membranes, which contain hundreds of lipid species. How viruses sense lipid compositions to target suitable host cells is poorly understood. Using multi-scale molecular simulations, we computed 66 membrane binding free energies of fusion proteins…
Ping Zhu, Hanspeter Winkler, Elena Chertova, Kenneth A. Taylor + 2 more
'Kenneth H. Roux' 'Michael Farzan'] A detailed understanding of the morphology of the HIV-1 envelope (Env) spike is key to understanding viral pathogenesis and for informed vaccine design. We have previously presented a cryoelectron microscopic tomogram (cryoET) of the Env spikes on SIV virions. Several structural…
Sanika Dolas, Gaurav Sharma
According to the World Health Organization, the number of people infected with COVID-19 continues to increase globally, highlighting the urgent need for effective treatments. Research has shown that certain antibodies targeting the envelope (E) protein of the virus can prevent viral entry. This study aimed to…
Mustafa Arif, Gaurav Sharma
HIV (human immunodeficiency virus) is a virus that attacks the immune system, which serves as the body’s defense mechanism. If untreated, HIV can lead to AIDS (acquired immunodeficiency syndrome), which raises risk for a host of problems, especially infections and cancers. According to data from 2022, there are 39…
Chenxi Sui, Jiankun Pu, Ting-Hsuan Chen, Yi-Ting Lai + 5 more
Radiative thermoregulation has been considered a promising approach for reducing the heating, ventilation, and air-conditioning (HVAC) energy consumption of buildings and solving the global climate change issues. Electrochromism is a powerful way to dynamically control the heat balance of buildings in response to…
Xudong Ouyang, Jelmer Hoeksma, Tjalling K. Siersma, Leendert W. Hamoen + 1 more
Antimicrobial resistance is a major threat to human health. Basic knowledge of antimicrobial mechanism of action (MoA) is imperative for patient care and for identification of novel antimicrobials. However, the process of antimicrobial MoA identification is relatively laborious. Here, we developed a simple…
Ahanjit Bhattacharya, Nahal Bagheri, Steven G. Boxer
Fusion of enveloped viruses with endosomal membranes and subsequent release of viral genome into the cytoplasm is crucial to the viral infection cycle. It is often modelled by carrying out fusion between virus particles and target lipid vesicles. We utilized fluorescence microscopy to characterize the kinetic and…
David H. Klinges, Ilya M. D. Maclean, Brett R. Scheffers
Scientists have long categorized the planet’s climate using the Köppen-Geiger (KG) classification to understand climate change impacts, biogeographical realms, agricultural suitability, and conservation. However, global KG maps primarily rely on macroclimate data collected by weather stations, which may not represent…