16 papers · ranked by Valyu relevance
Haleema Anwar, Qudsia Umaira Khan, Natasha Nadeem, Iqra Pervaiz + 2 more
'Muhammad Ali' 'Fatima Fayyaz Cheema'] Epilepsy is a condition marked by abnormal neuronal discharges or hyperexcitability of neurons with synchronicity and is recognized as a major public health concern. The pathology is categorized into three subgroups: acquired, idiopathic, and epilepsy of genetic or developmental…
Aida Mihaela Manole, Carmen Adella Sirbu, Mihaela Raluca Mititelu, Octavian Vasiliu + 4 more
'Octavian Vasiliu' 'Lorenzo Lorusso' 'Octavian Mihai Sirbu' 'Florentina Ionita Radu' 'Chiara Villa'] Epilepsy is a common condition worldwide, with approximately 50 million people suffering from it. A single seizure does not mean epilepsy; almost 10% of the population can have a seizure during their lifetime. In…
Alexander Muacevic, John R Adler, Abdullah Ahmed, Abdul-Habib Rahman + 6 more
'Shimul Williams' 'Mubeen Toufiq' 'Eyad Jamileh' 'Sheema Chaudhry' 'Khadijah Ahmed' 'Munir Ahmed'] Epilepsy is a common neurological disorder impacting millions globally, marked by recurrent, unprovoked seizures. This review article, tailored for UK medical students, provides a broad clinical overview of epilepsy…
Puja Patel, Solomon L. Moshé
This review aims to highlight the historical hallmarks in the development of the concepts of seizures and epilepsy. It begins with a discussion of seizure semiology and terminology, followed by the pathophysiology of seizures. We then discuss the definition of epilepsy, its etiologies, and ultimately classification…
Alexander Muacevic, John R Adler, Pranvera Hoxhaj, Sana K Habiya + 10 more
'Rithika Sayabugari' 'Roghan Balaji' 'Roshni Xavier' 'Arghal Ahmad' 'Mousumi Khanam' 'Meet Popatbhai Kachhadia' 'Tirath Patel' 'Zain U Abdin' 'Ali Haider' 'Zahra Nazir'] It has been noted that people who have epilepsy have an increased propensity for cognitive dysfunction. We explored 25 relevant articles on PubMed and…
Abbas Tafakhori, Vajiheh Aghamollaii, Sara Faghihi-Kashani, Payam Sarraf + 1 more
'Payam Sarraf' 'Laleh Habibi'] Epilepsy is one of the most common neurological disorders. Studies have demonstrated that genetic factors have a strong role in etiology of epilepsy. Mutations in genes encoding ion channels, neurotransmitters and other proteins involved in the neuronal biology have been recognized in…
Sanobar Shariff, Halah A. Nouh, Samuel Inshutiyimana, Charbel Kachouh + 4 more
1## INTRODUCTION The medical condition of epilepsy is characterized by two or more seizure episodes and uncontrolled and unprovoked firing of the brain neurons. This chronic disease is noncommunicable, and it affects an estimated number of 50 million people, all ages included, globally., Seizures result from inadequate…
Shampa Ghosh, Jitendra Kumar Sinha, Tarab Khan, Kuramkote Shivanna Devaraju + 4 more
'Kuramkote Shivanna Devaraju' 'Prabhakar Singh' 'Kumar Vaibhav' 'Pankaj Gaur' 'Jacopo Meldolesi'] Epilepsy affects around 50 million people across the globe and is the third most common chronic brain disorder. It is a non-communicable disease of the brain that affects people of all ages. It is accompanied by…
Jaya Kumar, Amro Solaiman, Pasuk Mahakkanukrauh, Rashidi Mohamed + 1 more
'Srijit Das'] In the last several decades, sleep-related epilepsy has drawn considerable attention among epileptologists and neuroscientists in the interest of new paradigms of the disease etiology, pathogenesis and management. Sleep-related epilepsy is nocturnal seizures that manifest solely during the sleep state.…
Sahithi Madireddy, Samskruthi Madireddy, Chandra Prakash, Deepak Sharma + 1 more
'Deepak Sharma' 'Pavan Kumar'] Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures that affects 50 million individuals globally. Because approximately one-third of patients with epilepsy do not respond to drug therapy, the development of new therapeutic strategies against epilepsy…
Alexander Muacevic, John R Adler, Tara Sabzvari, Muhammed Aflahe Iqbal + 8 more
'Muhammed Aflahe Iqbal' 'Akash Ranganatha' 'Jean C Daher' 'Isabel Freire' 'Syeda Maham Fatima Shamsi' 'Oriona Vinishia Paul Anthony' 'Anusha G Hingorani' 'Aparita S Sinha' 'Zahra Nazir'] Epilepsy is a neurological disorder that affects millions of people worldwide, with a significant proportion of patients experiencing…
H. V. Srinivas
Epilepsy is a common neurological disease accounting for 1% of global burden of disease (WHO). This equals lung cancer in men and breast cancer in women. In India it is estimated to have 60-80 lakhs of people with epilepsy. Eventhough epilepsy is known to mankind for several thousands of years, it is only in the last…
Alexander Muacevic, John R Adler, Seraj Makkawi, Fahad S Alshehri + 7 more
'Abdulrahman A Malaikah' 'Abdulkarim M Alghamdi' 'Raghad M Al-Zahrani' 'Rana J Nahas' 'Muhammad A Khan' 'Alqassem Y Hakami' 'Duaa A Babaer'] Background Epilepsy is a chronic neurologic condition with different risk factors and genetic predispositions. It is characterized by the occurrence of an epileptic seizure. To…
Ajith Cherian, Sanjeev V. Thomas
Status epilepticus (SE) is a medical emergency associated with significant morbidity and mortality. SE is defined as a continuous seizure lasting more than 30 min, or two or more seizures without full recovery of consciousness between any of them. Based on recent understanding of the pathophysiology, it is now…
Sadaf Afif, Syeda Tayyaba Rehan, Hassan ul Hussain, Md. Saiful Islam
Approximately 80% of patients with epilepsy reside in poor resource settings. Despite the continued advancements and development of new treatment approaches, epilepsy remains a major health problem in developing countries. Consistent findings of epidemiologic studies reflect that both prevalence and treatment gap are…
Mekdes Tigistu, Telake Azale, Habtamu Kebebe, Temesgen Yihunie
Objective About three-fourth of adults with new-onset epilepsy become seizure-free with current anti-epileptic drugs, but around one-fourth of the patients continue to experience seizure which increases the risk of accident, disability, death and treatment side effects. Therefore, this study aimed to address the gap in…