25 papers · ranked by Valyu relevance
Ana A. Rentería-Palomo, Jose L. Montes-Ochoa, Adriana Martinez-Mayorga, Jorge Guillermo Reyes-Vaca + 1 more
'Adriana Martinez-Mayorga' 'Jorge Guillermo Reyes-Vaca' 'Ildefonso Rodríguez-Leyva'] Objective: The objective of this study was to determine the relationship between atrophy of the hippocampus and severity of epilepsy in patients with temporal lobe epilepsy (TLE) as the first step to evaluate the possibility of surgery…
Muhammad Shoaib Farooq, Aimen Zulfiqar, Shamyla Riaz
Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been conducted to support automatic diagnosis of epileptic seizures for the ease of…
Kristin M. Gunnarsdottir, Adam Li, Rachel J. Smith, Joon-Yi Kang + 12 more
Over 15 million epilepsy patients worldwide have medically refractory epilepsy (MRE), i.e., they do not respond to anti-epileptic drugs. Successful surgery is a hopeful alternative for seizure freedom but can only be achieved through complete resection or disconnection of the epileptogenic zone (EZ), the brain…
Bahareh Salafian, Eyal Fishel Ben-Knaan, Nir Shlezinger, Sandrine de Ribaupierre + 1 more
'Sandrine de Ribaupierre' 'Nariman Farsad'] Abstract—We develop a hybrid model-based data-driven seizure detection algorithm called Mutual Information-based CNN-Aided Learned factor graphs (MICAL) for detection of eclectic seizures from EEG signals. Our proposed method contains three main components: a neural mutual…
Alexander Muacevic, John R Adler, Abdullah Ahmed, Abdul-Habib Rahman + 6 more
'Shimul Williams' 'Mubeen Toufiq' 'Eyad Jamileh' 'Sheema Chaudhry' 'Khadijah Ahmed' 'Munir Ahmed'] Epilepsy is a common neurological disorder impacting millions globally, marked by recurrent, unprovoked seizures. This review article, tailored for UK medical students, provides a broad clinical overview of epilepsy…
Alexander Muacevic, John R Adler, Pranvera Hoxhaj, Sana K Habiya + 10 more
'Rithika Sayabugari' 'Roghan Balaji' 'Roshni Xavier' 'Arghal Ahmad' 'Mousumi Khanam' 'Meet Popatbhai Kachhadia' 'Tirath Patel' 'Zain U Abdin' 'Ali Haider' 'Zahra Nazir'] It has been noted that people who have epilepsy have an increased propensity for cognitive dysfunction. We explored 25 relevant articles on PubMed and…
Alhamdu Adamu, Rui Chen, An Li, Guofang Xue
Epilepsy affects 50 million people worldwide. Nearly 80% of people with epilepsy live in resource-constrained low-income and middle-income countries. In Asia, which has a population of over 4 billion or has 50% of the world's population, about 23 million people have epilepsy. In this review, we discuss the difficulties…
Ali K. Saad, Nadia Akawi
Background Monogenic epilepsies are a group of rare disorders that manifest in early childhood and are usually associated with neurodevelopmental abnormalities and poor drug response. The field of genetic epilepsy is continuously evolving in alignment with the vast advancements in genetic testing in the last decade.…
Rita Pontes Silva, João Gama Marques
This review aims to estimate the prevalence of seizures and epilepsy among homeless people in current literature as well as understand the main adversities that this group withstands. We conducted a search for “epilep”, “seizur”, and “homeles*” in titles and abstracts of articles in PubMed. Overall, 25 articles met the…
José Luis Hernández-Cáceres, Liudmila Lukianenko, Elena Venskaya, Yury D. Nechipurenko + 3 more
Epilepsy affects more than 52 million people worldwide and has been known since ancient times. Despite this long history, available therapeutic methods—both pharmacological and non-pharmacological—fail to control seizures in over 10% of patients. At the same time, there exists a diversity of theories regarding the…
Arsalan Heidarpanah
During the last three decades, many studies have been conducted in the field of treatment with non-invasive methods. In this way, researchers try to use alternative methods including the use of electromagnetic waves in the treatment of diseases. As a result, the therapeutic use of electromagnetic waves in the treatment…
Fatma El Abed, Ghada Baraket, Marion N. Nyamari, Careen Naitore + 1 more
Epilepsy is a neurological disease defined by episodes of synchronous convulsions. Recently, miRNAs have been proven as promising biomarkers for multiple ailments like tumors and neurodegenerative disorders; their role in epilepsy is still unclear. This study aimed to understand the involvement of miRNAs in the disease…
S. Martín-Suárez, JM Cortes, P. Bonifazi
Epilepsy, the condition of recurrent unprovoked seizures resulting from a wide variety of causes, is one of the world’s most prominent brain syndrome. Seizures which are an expression of neuronal network dysfunction occur in a positive feedback loop of concomitant factors where seizures generate more seizures…
Aravind Kumar Kamaraj, Matthew Parker Szuromi, Daniel Galvis, William Stacey + 2 more
Epileptic seizures are characterized by abnormal synchronous bursting of neurons. This is commonly attributed to an imbalance between excitatory and inhibitory neurotransmission. We introduce compartmental models from epidemiology to study this interaction between excitatory and inhibitory populations of neurons in the…
A I Bhatti
The prediction of epileptic seizure, like the disease itself, is a very old but largely unresolved problem. The prediction may highly improve the quality of life for an epileptic patient. A low cost measurement like Electroencephalogram (EEG) involves the non-invasive monitoring of the brain voltage signals to detect…
Sekhar Talluri
Epilepsy is a common disorder of the Central Nervous System. Although several drugs are available for treatment of epilepsy, none of them are applicable for all cases, and some have serious adverse affects. The rational design of small molecule drugs for disorders of the Central Nervous System is a difficult process…
Rafael Chitolina, Matheus Gallas-Lopes, Carlos G. Reis, Radharani Benvenutti + 4 more
The use of zebrafish as a model organism is gaining evidence in the field of epilepsy as it may help to understand the mechanisms underlying epileptic seizures. As zebrafish assays became popular, the heterogeneity between protocols increased, making it hard to choose a standard protocol to conduct research while also…
Salim Rukhsar, Anil Kumar Tiwari
Background: Epilepsy is a neurological illness affecting the brain that makes people more likely to experience frequent, spontaneous seizures. There has to be an accurate automated method for measuring seizure frequency and severity in order to assess the efficacy of pharmacological therapy for epilepsy. The drug…
Atefeh Khoshkhahtinat, Hoda Mohammadzade
—Epilepsy is a neurological disorder identified by sudden and recurrent seizures, which are believed to be accompanied by distinct changes in brain dynamics. Exploring the dynamic changes of brain network states during seizures can pave the way for improving the diagnosis and treatment of patients with epilepsy. In…
Miguel Bhagubai, Christos Chatzichristos, Lauren Swinnen, Jaiver Macea + 9 more
'Jaiver Macea' 'Jingwei Zhang' 'Lieven Lagae' 'Katrien Jansen' 'Andreas Schulze‐Bonhage' 'Francisco Sales' 'Benno Mahler' 'Yvonne G. Weber' 'Wim Van Paesschen' 'Maarten De Vos'] The increasing technological advancements towards miniaturized physiological measuring devices have enabled continuous monitoring of epileptic…
Zag ElSayed, Murat Özer, Nelly Elsayed
—A seizure tracking system is crucial for monitoring and evaluating epilepsy treatments. Caretaker seizure diaries are used in epilepsy care today, but clinical seizure monitoring may miss seizures. Monitoring devices that can be worn may be better tolerated and more suitable for long-term ambulatory use. Many…
Martyna Śliwińska, Anna Rakuś-Kwiatosz, Magdalena Chrościńska-Krawczyk, Guillermo Estivill-Torrús
Introduction: Epilepsy is a chronic brain disorder causing recurrent seizures as a result of abnormal electrical brain activity. Approximately 70 million people worldwide suffer from it and need antiseizure treatment. The diagnosis and assessment of the effectiveness of the therapy are mainly based on symptoms…
Junming Ren, Zhoujian Xiao, Yujia Zhang, Yujie Yang + 7 more
mouse model for anti-epilepsy drug screening Authors: ['Junming Ren' 'Zhoujian Xiao' 'Yujia Zhang' 'Yujie Yang' 'Ling He' 'Ezra Yoon' 'Stephen Temitayo Bello' 'Xi Chen' 'Dapeng Wu' 'Micky D. Tortorella' 'Jufang He'] Background: In the preclinical translational studies, drug candidates with remarkable anti-epileptic…
Authors not listed
The GluK1 receptor, an ionotropic glutamate receptor, operates as a ligand-gated ion channel. Opioids stand as the most potent pain-relieving medications currently prescribed in the medical field. Inhibiting this receptor is anticipated to result in a reduction of dopamine release in the Nucleus Accumbens, effectively…
Authors not listed
Researching the EEEV virus is challenging due to the virus's high lethality and significant risk. This study employed bioinformatics methods for domain search to investigate the pathogenesis and infection process of the EEEV virus P protein. The results demonstrated that the EEEV virus P protein contains domains that…