26 papers · ranked by Valyu relevance
Sanath Kumar Krishnamurthy, Susan Athey, Emma Brunskill
Technical Debt Authors: ['Sanath Kumar Krishnamurthy' 'Susan Athey' 'Emma Brunskill'] We formulate the problem of constructing multiple simultaneously valid confidence intervals (CIs) as estimating a high probability upper bound on the maximum error for a class/set of estimate-estimand-error tuples, and refer to this…
Huisi Tong, Hao Zhang, Huadong Meng, Xiqin Wang
Error bounds for nonlinear filtering are very important for performance evaluation and sensor management. This paper presents a comparative study of three error bounds for tracking filtering, when the detection probability is less than unity. One of these bounds is the random finite set (RFS) bound, which is deduced…
Anastasiia Izycheva, Eva Darulová
—State-of-the-art static analysis tools for verifying finite-precision code compute worst-case absolute error bounds on numerical errors. These are, however, often not a good estimate of accuracy as they do not take into account the magnitude of the computed values. Relative errors, which compute errors relative to the…
Ray-I Chang, Jui-Hua Tsai, Chia-Hui Wang, James (Jong Hyuk) Park
Since the power of transmitting one-bit data is higher than that of computing one thousand lines of code in IoT (Internet of Things) applications, it is very important to reduce communication costs to save battery power and prolong system lifetime. In IoT sensors, the transformation of physical phenomena to data is…
Alexandros Gezerlis, Martin Williams
This article discusses several erroneous claims which appear in textbooks on numerical methods and computational physics. These are not typos or mistakes an individual author has made, but widespread misconceptions. In an attempt to stop these issues from further propagating, we discuss them here, along with some…
Hongchun Sun, Min Sun, Yiju Wang
For the extended linear complementarity problem (ELCP), by virtue of a new residual function, we establish a new type of global error bound under weaker conditions. Based on this, we respectively obtain new global error bounds for the vertical linear complementarity problem and the mixed linear complementarity problem.…
Anna Foerster, Moritz Schiltenwolf, David Dignath, Roland Pfister
Binding and retrieval of stimulus features, response features, and their attentional weighting tune cognitive processing to situational demands. The two mechanisms promote successful actions, especially in situations in which such actions depend on controlled processing. Here we explored binding and retrieval of…
Bao-Gang Hu, Hong-Jie Xing
—The existing upper and lower bounds between entropy and error are mostly derived through an inequality means without linking to joint distributions. In fact, from either theoretical or application viewpoint, there exists a need to achieve a complete set of interpretations to the bounds in relation t o joint…
George M. Constantinides, Fredrik Dahlqvist, Zvonimir Rakamarić, Rocco Salvia
'Rocco Salvia'] Abstract. We present a detailed study of roundoff errors in probabilistic floating-point computations. We derive closed-form expressions for the distribution of roundoff errors associated with a random variable, and we prove that roundoff errors are generally close to being uncorrelated with their…
Ilse C. F. Ipsen, Hua Zhou
Probabilistic models are proposed for bounding the forward error in the numerically computed inner product (dot product, scalar product) between of two real n-vectors. We derive probabilistic perturbation bounds, as well as probabilistic roundoff error bounds for the sequential accumulation of the inner product. These…
Qiwei Yu, Joel D. Mallory, Anatoly B. Kolomeisky, Jiqiang Ling + 1 more
Living systems maintain a high fidelity in key biological processes through kinetic proofreading, a mechanism to preferentially remove incorrect substrates at the cost of energy dissipation and slower speed. Proofreading mechanisms must balance their demand for higher speed, fewer errors, and lower dissipation, but it…
Jacob Beal, Brian Teague, John T. Sexton, Sebastian Castillo-Hair + 4 more
Reliable, predictable engineering of cellular behavior is one of the key goals of synthetic biology. As the field matures, biological engineers will become increasingly reliant on computer models that allow for the rapid exploration of design space prior to the more costly construction and characterization of candidate…
Authors not listed
The rapid growth of worldwide computing power has transformed in silico chemistry into a discipline that is integrated into the daily work of many chemists. Nowadays, researchers find it increasingly straightforward to predict a wide range of molecular properties and chemi- cal processes at reasonable computational…
Roy M. Howard
A spline based integral approximation is utilized to define a sequence of approximations to the error function that converge at a significantly faster manner than the default Taylor series. The real case is considered and the approximations can be improved by utilizing the approximation for and with optimally chosen.…
Anna Foerster, Birte Moeller, Christian Frings, Roland Pfister
The cognitive system readily detects and corrects erroneous actions by establishing episodic bindings between representations of the acted upon stimuli and the intended correct response. If these stimuli are encountered again, they trigger the retrieval of the correct response. Thus, binding and retrieval efficiently…
Anna Foerster, Svante Linz, Birte Moeller, Maria Nemeth + 2 more
Perceptual and action representations consist of multiple independent features such as color and location of an encountered stimulus, or effector and direction of a performed action. Performing an action further establishes bindings between perceptual and action features, so that reencountering one feature retrieves…
Thierry Mora, Ilya Nemenman
Cells adapt to changing environments by sensing ligand concentrations using specific receptors. The accuracy of sensing is ultimately limited by the finite number of ligand molecules bound by receptors. Previously derived physical limits to sensing accuracy have assumed that the concentration was constant and ignored…
Arina Soboleva, Kailas S. Honasoge, Eva Molnárová, Anne-Marie Dingemans + 3 more
Evolutionary cancer therapy (ECT) applies principles of evolutionary game theory to prolong the effectiveness of cancer treatment by curbing the development of treatment resistance. It was shown to increase time to progression while decreasing the cumulative drug dose. ECT individually tailors treatment schedules for…
Yang Tian, Justin L. Gardner, Guoqi Li, Pei Sun
Information experiences complex transformation processes in the brain, involving various errors. A daunting and critical challenge in neuroscience is to understand the origin of these errors and their effects on neural information processing. While previous efforts have made substantial progresses in studying the…
Omer Markovitch, Juntian Wu, Otto Sijbren
Copying information is vital for life's propagation. Current life forms maintain a low error rate in replication using complex machinery to prevent and correct errors. However, primitive life had to deal with higher error rates, limiting its ability to evolve. Discovering mechanisms to reduce errors would alleviate…
Authors not listed
Solvated electrons are highly reactive species that can drive many high-energy redox reactions. This study presents an efficient computational method to calculate the electronic bound states of the solvated electron. In chemically hard solvents, the interaction with the solvated electron can be captured by a…
Robert Taylor, Paul M Bays
Observers reproducing elementary visual features from memory after a short delay produce errors consistent with the encoding-decoding properties of neural populations. While inspired by electrophysiological observations of sensory neurons in cortex, the population coding account of these errors is based on a…
Authors not listed
Development of meta-generalized gradient approximations (meta-GGAs) has generally led to more accurate density-functional approximations, albeit ones that have more stringent requirements for the quadrature grids that are used to evaluate the exchange-correlation energy. Here, we demonstrate that grid-induced errors…
Martín Carballo-Pacheco, Jonathan Desponds, Tatyana Gavrilchenko, Andreas Mayer + 4 more
Cells need to reliably sense external ligand concentrations to achieve various biological functions such as chemotaxis or signaling. The molecular recognition of ligands by surface receptors is degenerate in many systems leading to crosstalk between different receptors. Crosstalk is often thought of as a deviation from…
Authors not listed
State of the art in silico ∆∆G predictions for antibody-antigen complexes achieve an accuracy of ±1 kcal/mol. While this is sufficient for high throughput screening or affinity maturation, it is insufficient for assessing the criticality of post-translational modifications (PTMs) during clinical development. PTMs that…
Authors not listed
Quantities calculated from molecular simulations are often subject to an initial bias due to unrepresentative starting configurations. Initial data are usually discarded to reduce bias. Chodera's method for automated truncation point selection [J. Chem. Theory Comput. 2016, 12, 4, 1799–1805] is popular but has not been…