Search · four archives
Search · four archives
20 papers · ranked by Valyu relevance
Zahra Amirkhanzadeh Barandouzi, Angela R. Starkweather, Wendy A. Henderson, Adwoa Gyamfi + 1 more
'Wendy A. Henderson' 'Adwoa Gyamfi' 'Xiaomei S. Cong'] Cumulative evidence shows a linkage between gut microbiota pattern and depression through the brain-gut microbiome axis. The aim of this systematic review was to identify the alterations of the gut microbiota patterns in people with depression compared to healthy…
Alexander Muacevic, John R Adler, Therese Limbana, Farah Khan + 1 more
'Noha Eskander'] The gut microbiome serves an important role in the human body. Reportedly, one of the benefits of these microflora is on mental health. Once established, food and other dietary sources that enhance quality microbiome content in our gastrointestinal system will be a significant consideration in…
Meiling Wang, Zhaoqi Song, Shirong Lai, Furong Tang + 2 more
Depression is one of the most prevalent mental disorders today. Over the past decade, there has been considerable attention given to the field of gut microbiota associated with depression. A substantial body of research indicates a bidirectional communication pathway between gut microbiota and the brain. In this…
Ameer Luqman, Mei He, Adil Hassan, Mehtab Ullah + 6 more
Depression is considered a multifaceted and intricate mental disorder of growing concern due to its significant impact on global health issues. The human gut microbiota, also known as the “second brain,” has an important role in the CNS by regulating it through chemical, immunological, hormonal, and neurological…
Zihua Li, Jingxi Sun, Jinlong Yang, Panpan Han + 4 more
Depression, a psychiatric disorder with significant morbidity and mortality, has a complex etiology. Recent advances in microbiome research have highlighted the potential role of gut microbiota in depression pathogenesis. This study utilized shotgun metagenomic sequencing to compare the fecal microbiota of 28…
Alina Wilkowska, Łukasz Piotr Szałach, Wiesław Jerzy Cubała
According to the WHO, major depressive disorder is the leading cause of disability worldwide, and it is a major contributor to the overall global burden of disease. The pathophysiology of this common and chronic disease is still not completely understood. The gut microbiome is an increasingly recognized environmental…
Yuchen Zhang, Wenkai Lai, Meiling Wang, Shirong Lai + 3 more
Depression is a common mental disorder worldwide, and its pathogenesis remains incompletely understood. However, increasing evidence suggests that gut microbiota play a significant role in the development of depression through the gut-brain-microbiota axis. However, due to the substantial individual variability in gut…
Ahmed Eltokhi, Iris E. Sommer
Depression is a severe mental disorder that places a significant economic burden on public health. The reciprocal link between the trillions of bacteria in the gut, the microbiota, and depression is a controversial topic in neuroscience research and has drawn the attention of public interest and press coverage in…
Yangbo Zhang, Changwei Liu, Qi Zhu, Hui Wu + 3 more
Depression, a serious mental illness, is characterized by high risk, high incidence, persistence, and tendency to relapse, posing a significant burden on global health. The connection between depression and gut microbiota is an emerging field of study in psychiatry and neuroscience. Understanding the gut-brain axis is…
Xin Zhou, Ariel B. Ganz, Andre Rayner, Tess Yan Cheng + 10 more
Depression is a leading cause of disability worldwide yet its underlying factors, particularly microbial associations, are poorly understood. We examined the longitudinal interplay between the microbiome and immune system in the context of depression during an immersive psychosocial intervention. 142 multi-omics…
Madelaine Leitman, Will Katza, David Zhang, Shrey Pawar + 3 more
Altered serotonin signaling is a well-established contributor to depression, with the serotonin transporter gene (SERT) playing a critical role in regulating serotonin reuptake. Mice lacking SERT (SERT -/-) serve as a robust model for depression, exhibiting significant depressive-like behaviors compared to littermate…
Benjamin Wingfield, Sonya Coleman, T.M. McGinnity, Anthony J. Bjourson
'Anthony J. Bjourson'] Abstract—Microbiota profiles measure the structure of microbial communities in a defined environment (known as microbiomes). In the past decade, microbiome research has focused on health applications as a result of which the gut microbiome has been implicated in the development of a broad range…
Camile Bahi
As the world's primary morbidity factor, depression has a considerable impact on both an individual as well as a societal level. It is a complex and multifactorial mental health disorder, one whose pathophysiology is not yet fully understood. Despite their discovery several decades ago, classical antidepressants have…
Isabella Schapira, Lillian Russo-Savage, Terdha Narla, Maggie O'Neill + 3 more
Despite the fact that tryptophan is an essential amino acid that humans typically obtain through diet, there are several interesting tryptophan dynamics at play in the body. Quantifying and understanding these dynamics are crucial in studies of depression, autism spectrum disorder, and other disorders that involve…
Authors not listed
The intricate bidirectional communication between mitochondria and the gut microbiota – termed mitochondria-microbiome crosstalk – plays a pivotal role in regulating host metabolism, immune responses, and overall physiological homeostasis. Emerging evidence highlights how microbial-derived metabolites, such as…
Authors not listed
One Health seeks to integrate and balance the health of humans, animals, and environmental systems. These three spheres are intricately interconnected through microbiomes, which are universally present and exchange microbes and genes, influencing not only human and animal health but also key environmental…
Authors not listed
The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer. Here, we developed a gas chromatography-coupled to tandem mass spectrometry (GC-MS/MS) method for the quantification of…
Todor Koev, Hou Hei Chung, Caitlin Wright, Evie Banister + 2 more
The human gut has emerged as a highly promising candidate for predicting the onset of pathologies and monitoring disease pro-gression. The gut microbiota plays a crucial role in maintaining gut homeostasis, modulating immune responses, metabolizing nutri-ents and regulating host physiology. These functions have been…
Cristian Orgaz, Andrés Sánchez-Ruiz, Gonzalo Colmenarejo
Human gut microbial metabolites are currently undergoing much research due to their involvement in multiple biological processes important for health, including immunity, metabolism, nutrition, and the nervous system. Metabolites exert their effect through the interaction with host and bacterial proteins, suggesting…
Sana Yasin, Syed Asad Hussain, Sinem Aslan, Imran Raza + 2 more
'Muhammad Muzammel' 'Alice Othmani'] - A summary of clinical background of MDD and BD, Brain structure and EEG based brain activity, - EEG experimental protocols study for mental disorders diagnosis, - An extensive study of state-of-the-art shallow and deep neural networks models for EEG based clinical depression…