Search · four archives
Search · four archives
25 papers · ranked by Valyu relevance
Erico Tjoa, Cuntai Guan
—Recently, artificial intelligence and machine learning in general have demonstrated remarkable performances in many tasks, from image processing to natural language processing, especially with the advent of deep learning. Along with research progress, they have encroached upon many different fields and disciplines.…
Pantelis Linardatos, Vasilis Papastefanopoulos, Sotiris Kotsiantis
Recent advances in artificial intelligence (AI) have led to its widespread industrial adoption, with machine learning systems demonstrating superhuman performance in a significant number of tasks. However, this surge in performance, has often been achieved through increased model complexity, turning such systems into…
Bishwamittra Ghosh, Dmitry Malioutov, Kuldeep S. Meel
Machine learning has become omnipresent with applications in various safety-critical domains such as medical, law, and transportation. In these domains, high-stake decisions provided by machine learning necessitate researchers to design interpretable models, where the prediction is understandable to a human. In…
Berk Ustun, Cynthia Rudin
We present an integer programming framework to build accurate and interpretable discrete linear classification models. Unlike existing approaches, our framework is designed to provide practitioners with the control and flexibility they need to tailor accurate and interpretable models for a domain of choice. To this…
Sapan Agarwal, Corey Hudson
This work presents a new classifier that is specifically designed to be fully interpretable. This technique determines the probability of a class outcome, based directly on probability assignments measured from the training data. The accuracy of the predicted probability can be improved by measuring more probability…
Emmanuel Pintelas, Meletis Liaskos, Ioannis E. Livieris, Sotiris Kotsiantis + 1 more
'Sotiris Kotsiantis' 'Panagiotis Pintelas'] Image classification is a very popular machine learning domain in which deep convolutional neural networks have mainly emerged on such applications. These networks manage to achieve remarkable performance in terms of prediction accuracy but they are considered as black box…
Oded Rotem, Tamar Schwartz, Ron Maor, Yishay Tauber + 5 more
The success of deep learning in identifying complex patterns exceeding human intuition comes at the cost of interpretability. Non-linear entanglement of image features makes deep learning a “black box” lacking human meaningful explanations for the models’ decision. We present DISCOVER, a generative model designed to…
Mohammad Ennab, Hamid Mcheick, Jae-Ho Han
The lack of interpretability in artificial intelligence models (i.e., deep learning, machine learning, and rules-based) is an obstacle to their widespread adoption in the healthcare domain. The absence of understandability and transparency frequently leads to (i) inadequate accountability and (ii) a consequent…
Mara Graziani, Lidia Dutkiewicz, Davide Calvaresi, José Pereira Amorim + 12 more
'José Pereira Amorim' 'Katerina Yordanova' 'Mor Vered' 'Rahul Nair' 'Pedro Henriques Abreu' 'Tobias Blanke' 'Valeria Pulignano' 'John O. Prior' 'Lode Lauwaert' 'Wessel Reijers' 'Adrien Depeursinge' 'Vincent Andrearczyk' 'Henning Müller'] Since its emergence in the 1960s, Artificial Intelligence (AI) has grown to…
Joao Marques-Silva, Alexey Ignatiev
Recent years witnessed a number of proposals for the use of the so-called interpretable models in specific application domains. These include high-risk, but also safety-critical domains. In contrast, other works reported some pitfalls of machine learning model interpretability, in part justified by the lack of a…
D. Petkovic, A. Alavi, D. Cai, J. Yang + 1 more
Machine Learning (ML) is becoming an increasingly critical technology in many areas. However, its complexity and its frequent non-transparency create significant challenges, especially in the biomedical and health areas. One of the critical components in addressing the above challenges is the explainability or…
Adrian Erasmus, Tyler D. P. Brunet, Eyal Fisher
We argue that artificial networks are explainable and offer a novel theory of interpretability. Two sets of conceptual questions are prominent in theoretical engagements with artificial neural networks, especially in the context of medical artificial intelligence: (1) Are networks explainable, and if so, what does it…
Masrur Sobhan, Ananda Mohan Mondal
Lung cancer is the leading cause of cancer compared to other cancers in the USA despite being the most commonly diagnosed. The overall survival rate of lung cancer is not satisfactory even though having cutting edge treatment methods for cancers. Genomic profiling and biomarker gene identification of lung cancer…
Ping Yang, E. Adrian Henle, Cory M. Simon, Xiaoli Fern
Pesticides benefit agriculture by increasing crop yield, quality, and security. However, pesticides may inadvertently harm bees, which are valuable as pollinators. Thus, candidate pesticides in development pipelines must be assessed for toxicity to bees. Leveraging a data set of 382 molecules with toxicity labels from…
Authors not listed
Machine learning holds significant promise for accelerating biomarker discovery in clinical proteomics, yet its real-world impact remains limited by widespread methodological pitfalls and unrealistic expectations. In this perspective, we critically examine the integration of machine learning into clinical proteomics…
Amit Dhurandhar, Vijay S. Iyengar, Ronny Luss, Karthikeyan Shanmugam
We provide a novel notion of what it means to be interpretable, looking past the usual association with human understanding. Our key insight is that interpretability is not an absolute concept and so we define it relative to a target model, which may or may not be a human. We define a framework that allows for…
Vincent Margot
Interpretability is becoming increasingly important for predictive model analysis. Unfortunately, as remarked by many authors, there is still no consensus regarding this notion. The goal of this paper is to propose the definition of a score that allows to quickly compare interpretable algorithms. This definition…
Vivian Dos Santos Silva, André Freitas, Siegfried Handschuh
Artificial Intelligence models are becoming increasingly more powerful and accurate, supporting or even replacing humans' decision making. But with increased power and accuracy also comes higher complexity, making it hard for users to understand how the model works and what the reasons behind its predictions are.…
Authors not listed
Early-stage drug discovery often suffers from data scarcity and out-of-distribution (OOD) shifts, which constrain the reliability of predictive models. While deep learning has advanced representation learning from molecular and biological data, tabular modeling remains indispensable, particularly in small-sample and…
P. Karatza, Kalliopi Dalakleidi, Μαρία Αθανασίου, Konstantina S. Nikita
'Konstantina S. Nikita'] Abstract— Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide adoption in clinical practice. To address the…
Mehrshad Sadria, Anita Layton, Gary D. Bader
For predictive computational models to be considered reliable in crucial areas such as biology and medicine, it is essential for them to be accurate, robust, and interpretable. A sufficiently robust model should not have its output affected significantly by a slight change in the input. Also, these models should be…
Authors not listed
Ensuring the trustworthiness of machine learning (ML) models in high-stake applications is crucial. One such application is predicting anti-cancer drug sensitivity, where ML models are built with the final goal of integrating them into treatment recommendation systems for personalized medicine. Here, we propose a…
Raeuf Roushangar, George I. Mias
ClassificaIO is an open-source Python graphical user interface (GUI) for machine learning classification for the scikit-learn module. ClassificaIO aims to provide an easy-to-use interactive way to train, validate, and test data on a range of classification algorithms. The GUI enables fast comparisons within and across…
Prashanth Athri, Vidhya Murali, Pradyumna Y Muralidhar, Cassandra Königs + 4 more
- 1. Department of Computer Science and Engineering, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Bengaluru, India - 2. PES Center for Pattern Recognition, Department of Computer Science and Engineering, PES University, Bengaluru, India - 3. Bioinformatics and Medical Informatics, Bielefeld University…
Saer Samanipour, Jake O'Brien, Malcolm Reid, Kevin Thomas + 1 more
The European Chemicals Agency (ECHA) and US Environmental Protection Agency (EPA) have listed approximately 800k chemicals that must be further investigated for their potential environmental and/or human health risk. A significant number of these chemicals have large enough global volumes of consumption (e.g.…