20 papers · ranked by Valyu relevance
Zhien Feng, Qiao Shi Xu, Chong Wang, Jin Zhong Li + 4 more
'Hua Li' 'Li Zheng Qin' 'Zhengxue Han'] The lymph node ratio(LNR) has been described as a novel predictor of the survival of patients with oral and oropharyngeal squamous cell carcinoma(O/OPSCC). The purpose of this study was to evaluate whether LNR is better at predicting survival and the need for adjuvant treatment…
Arikin Abdeyrim, Shizhi He, Yang Zhang, Gulbostan Mamtali + 3 more
'Aibadla Asla' 'Mirkamil Yusup' 'Jiang Liu'] Background Several recent studies have indicated that the lymph node ratio (LNR) is an independent prognostic factor for laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC). The purpose of this paper is to assess the prognostic value of LNR and explore appropriate…
Yu-Long Wang, Duan-Shu Li, Yu Wang, Zhuo-Ying Wang + 2 more
'Renato Franco'] Background Lymph node metastasis has a significant impact on laryngeal cancer prognosis. The role of lymph node ratio (LNR, ratio of metastatic to examined nodes) in the staging of laryngeal cancer was not reported. Patients and Methods Records of laryngeal cancer patients with lymph node involvement…
William Castrucci, Donald Lannin, Bruce G. Haffty, Susan A. Higgins + 1 more
'Meena S. Moran'] Purpose. The value of nodal ratios (NRs) as a prognostic variable in breast cancer is continually being demonstrated. The purpose of this study was to use NR in patients with ≥4+ nodes to assess a correlation of NR with regional (lymph node) recurrence. Methods. Inclusion criteria was ≥8 nodes…
Nan Ding, ZhaoFei Pang, Xiangwei Zhang, Cuicui Huang + 3 more
'Qi Liu' 'Jiajun Du'] In the eighth TNM staging system proposal for NSCLC recently, classification of N stage is based on anatomical position of positive lymph nodes. We aimed to expand the sample volume to identify the value of positive lymph node number or ratio in prognosis and predictive effect for postoperative…
Breno Cordeiro PORTO, Marina Alessandra PEREIRA, Marcus Fernando Kodama Pertille RAMOS, André Roncon DIAS + 3 more
'Marcus Fernando Kodama Pertille RAMOS' 'André Roncon DIAS' 'Fábio Pinatel LOPASSO' 'Luiz Augusto Carneiro D’ALBUQUERQUE' 'Ulysses RIBEIRO JUNIOR'] Title: ABSTRACT BACKGROUND: Lymph node status is vital for gastric cancer (GC) prognosis, but the conventional pN stage may be limited by variations in lymphadenectomy and…
T Van Gorp, A J Kruse, B F Slangen, R F Kruitwagen
Sir, We read with interest the paper by [3] in which they evaluated the prognostic value of lymph node density (LND) in patients with lymph node-positive cervical cancer. LND is defined as the ratio of the number of metastatic lymph nodes to the total number of lymph nodes removed. They showed that LND>10% is…
Gemma van der Voort, Maike Effern, Michelle C. R. Yong, Lukas Kiwitz + 9 more
Reactive neutrophil infiltration can restrain CD8^+^ T cell expansion in lymph nodes during adoptive T cell therapy (ACT), yet its spatiotemporal regulation remains incompletely understood. Levaraging flow cytometry and multiplex immunofluorescence data, we performed a time-resolved quantitative assessment of immune…
Ann Ramirez, Vedanth Sriram, Yassmin Abbouchi, Reina Patolia + 3 more
Lymph nodes are highly specialized immune organs that orchestrate the adaptive immune response. In the lymph nodes, naïve B and T lymphocytes encounter cognate antigens, sparking their activation and response to foreign substances. Lymph nodes grow in response to an immune challenge, at least in part to accommodate…
Frank P. Assen, Miroslav Hons, Robert Hauschild, Shayan Shamipour + 12 more
Lymph nodes (LNs) comprise two main structural elements: Fibroblastic reticular cells (FRCs) that form dedicated niches for immune cell interaction and capsular fibroblasts that build a shell around the organ. While LNs are fairly stable in size during homeostatic conditions, immunological challenge causes more than…
Yongrui Yu, Hanyu Chen, Zitian Zhang, Qiong Xiao + 7 more
Segmentation Authors: ['Yongrui Yu' 'Hanyu Chen' 'Zitian Zhang' 'Qiong Xiao' 'Wenhui Lei' 'Linrui Dai' 'Yu Fu' 'Tan Hui' 'Guan Wang' 'Peng Gao' 'Xiaofan Zhang'] Abstract. Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided…
Xin SU, Ariane Brassard, Alexandra Bartolomucci, Iqraa Dhoparee-Dooma + 16 more
Lymph nodes (LNs) are frequently the first sites of metastasis. Currently, the only prognostic LN assessment is determining metastasis status. However, there is evidence suggesting that LN metastasis is facilitated by a pre-metastatic niche induced by tumour derived extracellular vehicles (EVs). Therefore, it is…
Ke Yan, Dakai Jin, Dazhou Guo, Minfeng Xu + 4 more
'Xianghua Ye' 'Le Lü'] Abstract. Finding abnormal lymph nodes in radiological images is highly important for various medical tasks such as cancer metastasis staging and radiotherapy planning. Lymph nodes (LNs) are small glands scattered throughout the body. They are grouped or defined to various LN stations according…
Maura C. Belanger, Alexander G. Ball, Megan A. Catterton, Andrew W.L. Kinman + 6 more
The lymph node is a highly organized and dynamic structure that is critical for facilitating the intercellular interactions that constitute adaptive immunity. Most ex vivo studies of the lymph node begin by reducing it to a cell suspension, thus losing the spatial organization, or fixing it, thus losing the ability to…
Tejas Sudharshan Mathai, Bohan Liu, Ronald M. Summers
Purpose: Lymph nodes (LNs) in the chest have a tendency to enlarge due to various pathologies, such as lung cancer or pneumonia. Clinicians routinely measure nodal size to monitor disease progression, confirm metastatic cancer, and assess treatment response. However, variations in their shapes and appearances make it…
Soukaina Sabir, Odelaisy León-Triana, Sergio Serrano, Roberto Barrio + 1 more
node Authors: ['Soukaina Sabir' 'Odelaisy León-Triana' 'Sergio Serrano' 'Roberto Barrio' 'Vı́ctor M. Pérez-Garcı́a'] CAR-T cell therapies have demonstrated significant success in treating B-cell leukemia in children and young adults. However, their effectiveness in treating B-cell lymphomas has been limited. Unlike…
Chaoyi Wu, Feng Chang, Xiao Su, Zhihan Wu + 3 more
'Ya Zhang'] Metastasis on lymph nodes (LNs), the most common way of spread for primary tumor cells, is a sign of increased mortality. However, metastatic LNs are time-consuming and challenging to detect even for professional radiologists due to their small sizes, high sparsity, and ambiguity in appearance. It is…
David Bouget, André Pedersen, Johanna Vanel, Haakon Olav Leira + 1 more
'Thomas Langø'] Purpose: As lung cancer evolves, the presence of enlarged and potentially malignant lymph nodes must be assessed to properly estimate disease progression and select the best treatment strategy. Following the clinical guidelines, estimation of short-axis diameter and mediastinum station are paramount for…
Tedi Ramaj, Xingfu Zou
We develop and analyze a mathematical model of oncolytic virotherapy in the treatment of melanoma. We begin with a special, local case of the model, in which we consider the dynamics of the tumour cells in the presence of an oncolytic virus at the primary tumour site. We then consider the more general regional model…
Mahya Aghaee, Victoria Cicchirillo, Milner, Rowan + 13 more
- 1. Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA. - 2. Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA. - 3. Department of Mathematics, College of Liberal Arts and Sciences, University of Florida…