19 papers · ranked by Valyu relevance
Cornelis Klop, Ruud Schreurs, Ailin M.J. Ackermans, Valerie G. Niehe + 4 more
Objective: To establish normative data for key morphometric measurements in prenatal mandibular development. Methods: Forty-two human embryonic and fetal specimens, ranging from 8 to 37 weeks of gestational age (GA), without known abnormalities, were selected. Mandibles were segmented on histologic, micro-CT, or MDCT…
Evan C. Brooks, Simon J.Y. Han, Christian Louis Bonatto Paese, Amya A. Lewis + 2 more
The mandible is composed of several musculoskeletal tissues including bone, cartilage, and tendon that require precise patterning to ensure structural and functional integrity. Interestingly, most of these tissues are derived from one multipotent cell population called cranial neural crest cells (CNCCs). How CNCCs are…
José María Bermúdez de Castro, María Martinón-Torres, Mark Jan Sier, Laura Martín-Francés + 1 more
'Laura Martín-Francés' 'David Frayer'] The description of a new skull (D4500) from the Dmanisi site (Republic of Georgia) has reopened the debate about the morphological variability within the genus Homo. The new skull fits with a mandible (D2600) often referred as ‘big’ or ‘enigmatic’ because of its differences with…
Julia C. Boughner
and Great Ape ( Pan paniscus and P. troglodytes ) Mandibles: Possible Ontogenetic Strategies and Solutions Authors: Julia C. Boughner While mandible proportions do not appear to constrain permanent molar initiation times, how adequate space is created in the corpus for these teeth in a timely way is not well…
Maria Hovorakova, Herve Lesot, Miroslav Peterka, Renata Peterkova
In this review, classical data on the early steps in human odontogenesis are summarized and updated with specific insights into the development of the upper and lower embryonic jaws to help in understanding some oral pathologies. The initial step of human odontogenesis is classically characterized by two parallel…
Georgia Kotantoula, Ioannis A. Tsolakis, Ioannis Lyros, Miltiadis A. Makrygiannakis + 4 more
Simple Summary Facial symmetry is a crucial determinant of facial appearance; treatment of asymmetry can be challenging. When it comes to the mandible’s development the muscles play a significant role in the development and growth direction of the mandible. However, it is unclear how the masticatory muscles contribute…
Kimberly E. Inman, Patricia Purcell, Tsutomu Kume, Paul A. Trainor + 1 more
'Gregory S. Barsh'] Syngnathia (bony fusion of the upper and lower jaw) is a rare human congenital condition, with fewer than sixty cases reported in the literature. Syngnathia typically presents as part of a complex syndrome comprising widespread oral and maxillofacial anomalies, but it can also occur in isolation.…
Daniel J. Paluh, Madeline Brinkman, Kyliah Gilliam-Beale, Daniela Salcedo-Recio + 3 more
Teeth have been a prominent feature of most vertebrates for 400 million years, and the core regulatory network underlying embryonic tooth formation is deeply conserved from fishes to amniotes. In frogs, however, odontogenesis is delayed, occurring instead during the postembryonic metamorphosis. Nearly all adult frogs…
Claudia Compagnucci, Michael J. Depew
Gnathostome jaw patterning involves focal instructive signals from the embryonic surface cephalic ectoderm (SCE) to a fungible population of cranial neural crest. The spatial refinement of these signals, particularly for those patterning the upper jaws, is not fully understood. We demonstrate that Foxg1, broadly…
Miki Shimizu, Nicolas Narboux-Nême, Yorick Gitton, Camille de Lombares + 11 more
During gnathostome development, lower and upper jaws derive from the first pharyngeal arch (PA1), a complex structure constituted by Neural Crest Cells (NCCs), mesodermal, ectodermal and endodermal cell populations. Lower jaw (mandibular) identity depends on endothelin-1 (Edn1)-mediated activation of Dlx5/6 in PA1…
Neal Anthwal, Abigail S Tucker
The novel mammalian jaw joint, known in humans as the temporomandibular joint or TMJ, is cushioned by a fibrocartilage disc. This disc is secondarily absent in therian mammals that have lost their dentition, such as giant anteaters and some baleen whales. The disc is also absent in all monotremes. However, it is not…
Agnieszka Anna Tomaka, Krzysztof Domino, Dariusz Pojda, Michał Tarnawski
A computational method for quantitative analysis of temporomandibular joint (TMJ) configuration using occlusal positioning splints is proposed and demonstrated. The method models a positioning splint as a physical realization of a predefined rigid transformation of the mandible, derived from multimodal data, including…
Héctor E. Ramírez-Chaves, Stephen W. Wroe, Lynne Selwood, Lyn A. Hinds + 4 more
The tympanic ring, malleus and incus of the mammalian middle ear derive from the ancestral primary jaw joint of land vertebrates. In Mesozoic mammals, evolutionary detachment of the mammalian middle ear from the lower jaw occurred when Meckel’s cartilage - the last connection between the middle ear bones and the…
Jürgen Wallner, Kerstin Hochegger, Xiaojun Chen, Irene Mischak + 7 more
1 Department of Oral & Maxillofacial Surgery, Medical University of Graz, Auenbruggerplatz 5/1, Graz, Austria, 2 Computer Algorithms for Medicine (Cafe) Laboratory, Graz, Austria, 3 Institute for Computer Graphics and Vision, Graz University of Technology, Inffeldgasse 16c/II, Graz, Austria, 4 School of Mechanical…
Karyna Isaieva, Justine Leclère, Guillaume Paillart, Guillaume Drouot + 3 more
'Guillaume Drouot' 'Jacques Felblinger' 'Xavier Dubernard' 'Pierre‐André Vuissoz'] Twenty healthy subjects underwent real-time MRI while opening and closing their jaws. One axial and two sagittal slices were segmented using a U-Net-based algorithm. The centers of mass of the resulting masks were projected onto the…
Xiaojun Chen, Xing Li, Lu Xu, Yi Sun + 2 more
'Jan Egger'] In the orthognathic surgery, dental splints are important and necessary to help the surgeon reposition the maxilla or mandible. However, the traditional methods of manual design of dental splints are difficult and time-consuming. The research on computer-aided design software for dental splints is rarely…
Marie Sémon, Laurent Guéguen, Coraline Petit, Carine Rey + 3 more
In evolution, it is widely believed that phenotypic changes root in developmental changes and phenotype conservation, in developmental conservation. Seeming phenotype conservation may however hide evolutionary changes in the underlying developmental mechanisms by which a trait is produced. This cryptic evolution is…
Jorma Järnstedt, Jaakko Sahlsten, Joel Jaskari, Kimmo Kaski + 7 more
'Helena Mehtonen' 'Ari Hietanen' 'Osku Sundqvist' 'Vesa Varjonen' 'Vesa Mattila' 'Sangsom Prapayasotok' 'Sakarat Nalampang'] Preoperative radiological identification of mandibular canals is essential for maxillofacial surgery. This study demonstrates the reproducibility of a deep learning system (DLS) by evaluating its…
Alessandro Riga, Maria Giovanna Belcastro, Jacopo Moggi‐Cecchi
Development is a complex phenomenon where the forming phenotype interacts with genetic and environmental inputs. Teeth are an important model for developmental studies and their development has been thoroughly investigated. However, despite of an extensive literature on the genetics of dental development, no studies…