16 papers · ranked by Valyu relevance
Claudio Tomi-Andrino, Rupert Norman, Thomas Millat, Philippe Soucaille + 4 more
Metabolic engineering in the post-genomic era is characterised by the development of new methods for metabolomics and fluxomics, supported by the integration of genetic engineering tools and mathematical modelling. Particularly, constraint-based stoichiometric models have been widely studied: (i) flux balance analysis…
Claudio Tomi-Andrino, Rupert Norman, Thomas Millat, Philippe Soucaille + 5 more
'Philippe Soucaille' 'Klaus Winzer' 'David A. Barrett' 'John King' 'Dong-Hyun Kim' 'Costas D. Maranas'] Metabolic engineering in the post-genomic era is characterised by the development of new methods for metabolomics and fluxomics, supported by the integration of genetic engineering tools and mathematical modelling.…
Ka Moustapha, Druillennec Sabine, Chabi Sara, Roullé Céline + 13 more
Mafa is a critical transcription factor in pancreatic beta-cell biology, orchestrating insulin expression in response to glucose elevations. As a member of the large MAF protein family, MAFA’s stability and activity are intricately regulated by GSK3-mediated phosphorylation. To decipher the functional roles of these…
Emily M. Walker, Xin Tong, Jeeyeon Cha, Min Guo + 9 more
A heterozygous missense variant in the islet β-cell-enriched MAFA (Ser(S)64Phe(F)) transcription factor was identified in humans who developed either diabetes or insulinomatosis, with males more prone to diabetes. This mutation engenders increased stability to the normally unstable MAFA protein. To obtain insight into…
Zachary Loyd, Dongsoo Lee, Mallory Maurer, Lizabeth Buzzelli + 7 more
Pancreatic β-cells require the coordinated expression of transcription factors such as MAFA to dynamically secrete insulin to maintain euglycemia. A naturally occurring mutation in MAFA (MAFA^S64F^) produces a long-lived variant protein which predisposes carriers to dichotomous conditions of either maturity…
Yihan Hu, Yiheng Lin, Wei Wang, Yao Zhao + 2 more
'Humphrey Shi'] Abstract. Existing natural image matting algorithms inevitably have flaws in their predictions on difficult cases, and their one-step prediction manner cannot further correct these errors. In this paper, we investigate a multi-step iterative approach for the first time to tackle the challenging natural…
Xuelong Li, Kang Liu, Yongsheng Dong, Dacheng Tao
—Image matting is generally modeled as a space transform from the color space to the alpha space. By estimating the alpha factor of the model, the foreground of an image can be extracted. However, there are some dimensional information redundancy in the alpha space. It usually leads to the misjudgments of some pixels…
Authors not listed
Trifluoroacetic acid (TFA) is a persistent and mobile substance that has been increasing in concentrations within diverse environmental media, including rain, soils, human serum, plants, plant-based foods, and drinking water. Currently, TFA concentrations are orders of magnitude higher than those of other per- and…
Emma Carey, Francesca Hill, Amy Devine, Dénes Szűcs
Mathematics anxiety (MA) can be observed in children from primary school age into the teenage years and adulthood, but many MA rating scales are only suitable for use with adults or older adolescents. We have adapted one such rating scale, the Abbreviated Math Anxiety Scale (AMAS), to be used with British children aged…
Truong Son Hy, Thieu Khang, Risi Kondor
Optimization and Evolutionary Metaheuristics Authors: ['Truong Son Hy' 'Thieu Khang' 'Risi Kondor'] Multiresolution Matrix Factorization (MMF) is unusual amongst fast matrix factorization algorithms in that it does not make a low rank assumption. This makes MMF especially well suited to modeling certain types of graphs…
Kinga Morsanyi, Irene C. Mammarella, Dénes Szücs, Carlo Tomasetto + 2 more
Mathematical anxiety (MA) is a feeling of apprehension and fear related to mathematics (e.g., Ashcraft, ). High levels of MA have serious implications for a person's life prospects, as they can lead to an avoidance of elective maths courses, which, in turn, affects people's career opportunities (e.g., Hembree, ). The…
Sweta Ojha, P. Travis Thompson, Christian D. Powell, Hunter N.B. Moseley + 1 more
Per- and polyfluoroalkyl substances (PFAS) contamination in water sources near potential PFAS users is well known. Therefore, it is useful for PFAS stakeholders to visualize hot-spot areas and bring attention to the water systems that are near to those areas. Towards this end, we extracted information about PFAS…
Silvia Joseph, Irwandi Hipiny, Hamimah Ujir
Borneo indigenous communities are blessed with rich craft heritage. One such examples is the Iban's plaited mat craft. There have been many efforts by UNESCO and the Sarawak Government to preserve and promote the craft. One such method is by developing a mobile app capable of recognising the different mat motifs. As a…
Di Wu, Peng Zhang, Yi He, Xin Luo
1 Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China. 2 Institute of Artificial Intelligence and Blockchain, Guangzhou University, Guangzhou 510006, Guangdong, China. 3 School of Computer Science and Technology, Chongqing University of Posts and…
Mariaelena Bottazzi Schenone, Carlo Cavicchia, Maurizio Vichi, Giorgia Zaccaria
This article introduces a novel methodology to model the hierarchical dependence structure of manifest variables (MVs). This is done by reconstructing their correlation matrix considering a hierarchy of latent factors which forms an ultrametric correlation matrix. The proposed ultrametric factor analysis model will be…
Aleksandra Kołodziej, Mikołaj Magnuski, Anastasiia Ruban, Aneta Brzezicka
Frontal alpha asymmetry (FAA) is one of the most common electrophysiological measures in research on depressive disorders (DD). Many previous studies reported a relatively higher alpha band power in the left versus right frontal channels (left-sided FAA) in people with DD compared to healthy controls. Recently…