25 papers · ranked by Valyu relevance
Kevin Kauth, Tim Stadtmann, Vida Sobhani, Tobias Gemmeke
Introduction Research in the field of computational neuroscience relies on highly capable simulation platforms. With real-time capabilities surpassed for established models like the cortical microcircuit, it is time to conceive next-generation systems: neuroscience simulators providing significant acceleration, even…
Jinxian Guo, Xiaotian Feng, Peiyu Yang, Zhifei Yu + 3 more
'Chun-Hua Yuan' 'Weiping Zhang'] Quantum memories are essential for quantum information processing. Techniques have been developed for quantum memory based on atomic ensembles. The atomic memories through optical resonance usually suffer from the narrow-band limitation. The far off-resonant Raman process is a promising…
Corentin Ferry, Tomofumi Yuki, Steven Derrien, Sanjay Rajopadhye
—Offloading compute-intensive kernels to hardware accelerators relies on the large degree of parallelism offered by these platforms. However, the effective bandwidth of the memory interface often causes a bottleneck, hindering the accelerator's effective performance. Techniques enabling data reuse, such as tiling…
Zeke Wang, Hongjing Huang, Jie Zhang, Gustavo Alonso
—FPGAs are starting to be enhanced with High Bandwidth Memory (HBM) as a way to reduce the memory bandwidth bottleneck encountered in some applications and to give the FPGA more capacity to deal with application state. However, the performance characteristics of HBM are still not well specified, especially in the…
Ruiyong Zhao, Yibo Hu, Jing Chen, Viktor Sverdlov + 2 more
DRAM-based in-memory computing integrates computational regions into the main memory, enabling local data processing within the memory, thereby achieving faster and more efficient data computation. However, enhancing system performance requires addressing a critical challenge: achieving more general and sufficiently…
Francesco Cremonesi, Felix Schürmann
Computational modeling and simulation have become essential tools in the quest to better understand the brain’s makeup and to decipher the causal interrelations of its components. The breadth of biochemical and biophysical processes and structures in the brain has led to the development of a large variety of model…
Jing Wang, Chao Li, Taolei Wang, Jinyang Guo + 3 more
'Yiming Zhuansun' 'Minyi Guo'] The growing scale of data requires efficient memory subsystems with large memory capacity and high memory performance. Disaggregated architecture has become a promising solution for today's cloud and edge computing for its scalability and elasticity. As a critical part of disaggregation…
Bülent Abali, Richard J. Eickemeyer, Hubertus Franke, Chung‐Sheng Li + 1 more
'Marc A. Taubenblatt'] The "Disaggregated Server" concept has been proposed for datacenters where the same type server resources are aggregated in their respective pools, for example a compute pool, memory pool, network pool, and a storage pool. Each server is constructed dynamically by allocating the right amount of…
Young Choi, Yuze Chi, Jie Wang, Licheng Guo + 1 more
With the recent release of High Bandwidth Memory (HBM) based FPGA boards, developers can now exploit unprecedented external memory bandwidth. This allows more memory-bounded applications to benefit from FPGA acceleration. However, we found that it is not easy to fully utilize the available bandwidth when developing…
Vinson Young, Sanjay Kariyappa, Moinuddin K. Qureshi
—This paper investigates hardware-based memory compression designs to increase the memory bandwidth. When lines are compressible, the hardware can store multiple lines in a single memory location, and retrieve all these lines in a single access, thereby increasing the effective memory bandwidth. However, relocating and…
Arun Subramaniyan, Jack Wadden, Kush Goliya, Nathan Ozog + 4 more
Read alignment is a time-consuming step in genome sequence analysis. In the read alignment software BWA-MEM and the recently published faster version BWA-MEM2, the seeding step is a major bottleneck, for instance, contributing 38% to the overall execution time in BWA-MEM2 when aligning single-end whole human genome…
Nan Ding, Pieter Maris, Hai Ah Nam, Taylor Groves + 6 more
'LeAnn Lindsey' 'Christopher Daley' 'Oğuz Selvitopi' 'Leonid Oliker' 'Nicholas J. Wright'] Disaggregated memory is a promising approach that addresses the limitations of traditional memory architectures by enabling memory to be decoupled from compute nodes and shared across a data center. Cloud platforms have deployed…
Miguel Ruiz-Cabello N., Maksims Abaļenkovs, Luis M. Diaz Angulo, Clemente Cobos Sanchez + 3 more
'Clemente Cobos Sanchez' 'Franco Moglie' 'Salvador G. Garcia' 'Rashid Mehmood'] This work provides an in-depth computational performance study of the parallel finite-difference time-domain (FDTD) method. The parallelization is done at various levels including: shared- (OpenMP) and distributed- (MPI) memory paradigms…
Kanchan Verandani
In this paper, we explore the compute and memory characteristics of the FM-index and identify data movement as a significant contributor to overall energy consumption in genomic processing. We propose GeneF, a Processing-in-Memory (PIM) accelerator designed specifically for DNA alignment tasks, leveraging 3D-stacked…
Bastian Wiederhold
As anyone who has tried to memorize a one-hundred-digit number can attest, acquisition of numerical information typically proceeds at less than one bit/s. If human memory operated at this speed in general, even a simple conversation would not be possible. Indeed, through techniques such as the memory palace, which…
James C Knight, Thomas Nowotny
Large-scale simulations of spiking neural network models are an important tool for improving our understanding of the dynamics and ultimately the function of brains. However, even small mammals such as mice have on the order of 1 × 10^12^ synaptic connections which, in simulations, are each typically charaterized by at…
Bastian Wiederhold, Martin Stemmler, Andreas V.M. Herz
While our senses transmit information at rates exceeding 10^6^ bit/s, high-level cognitive processing is thought to be much slower, on the order of 10 bit/s regardless of the task^1^. It is unclear, though, whether this limit holds when the human mind is challenged. To test how fast one can process abstract…
Martin Wiener, Chloe Mondok, Alex Ma, Chetan Desai + 2 more
Visual stimuli are known to vary in their perceived duration, with some stimuli engendering so-called “time dilation” and others “time compression” effects. Previous theories have suggested these effects rely on the level of attention devoted to stimuli, magnitude of the stimulus dimension, or intensity of the…
Francisco J. H. Heras, John Anderson, Simon B. Laughlin, Jeremy E. Niven
Voltage-dependent conductances in many spiking neurons are tuned to reduce action potential energy consumption, so improving the energy efficiency of spike coding. However, the contribution of voltage-dependent conductances to the energy efficiency of analogue coding, by graded potentials in dendrites and non-spiking…
Fabian Strauss, Zhouxiaosong Zeng, Kai Braun, Marcus Scheele
Transition metal dichalcogenides (TMDCs) exhibit favorable properties for optical communication in the GHz regime, such as large mobilities, high extinction coefficients and silicon compatibility. While impressive improvements of their sensitivity have been realized, the bandwidths of these devices have been mostly…
V Shlyonsky, D Gall
We propose an upgraded version of our previously designed open-source lipid bilayer amplifier. This improved amplifier is now suitable both for the use in introductory courses in biophysics and neurosciences at the undergraduate level and for scientific research. Similar to its predecessor, the OpenPicoAmp-100k is…
Authors not listed
We demonstrate high-speed photodetectors based on bi-, few- and multilayered WSe2 flakes fabricated by high-resolution direct laser writing of Au top contacts from atomically precise gold nanoclusters as an alternative to conventional photolithography. Time-resolved steady-state and transient photoresponse measurements…
Authors not listed
Covalently tethering chromophores is an emerging strategy to control the structure and function of supramolecular aggregates for organic electronic applications. In this study, we employ first principle calculations to elucidate structure-property relationships in three perylene diimide (PDI) trimer systems: a…
Authors not listed
This paper develops a comprehensive theoretical framework for designing quantum memory systems with enhanced resilience to thermal decoherence through engineered lattice geometries and protective structures. We formulate a unified mathematical description connecting material properties, geometric configurations, and…
Authors not listed
Mass spectrometry (MS) generates large datasets that are stored in increasingly optimized and complex file types, demanding technical expertise to extract information rapidly and easily. We wondered whether a simple structured query language (SQL) database could hold raw MS data and allow for easily readable queries…