27 papers · ranked by Valyu relevance
Marie Engelene J. Obien, Kosmas Deligkaris, Torsten Bullmann, Douglas J. Bakkum + 1 more
'Douglas J. Bakkum' 'Urs Frey'] Microelectrode arrays and microprobes have been widely utilized to measure neuronal activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate neurons at multiple sites simultaneously. However, unlike the single-cell or single-channel resolution of…
Gerard O’Leary, Iouri Khramtsov, Rakshith Ramesh, Aidan Perez-Ignacio + 5 more
Bioelectronic interfaces have the potential to revolutionize the treatment of medical disorders and augment physiology. Implantable devices such as pacemakers and deep brain stimulators have already been deployed to control activity in diseases including Parkinson’s disease and epilepsy. These devices typically operate…
Katarzyna M. Szostak, Laszlo Grand, Timothy G. Constandinou
Implantable neural interfaces for central nervous system research have been designed with wire, polymer, or micromachining technologies over the past 70 years. Research on biocompatible materials, ideal probe shapes, and insertion methods has resulted in building more and more capable neural interfaces. Although the…
Elton Ho, Mark Hettick, Demetrios Papageorgiou, Adam J. Poole + 7 more
Progress toward the development of brain–computer interfaces has signaled the potential to restore, replace, or augment lost or impaired neurological function in a variety of disease states. Existing brain–computer interfaces rely on invasive surgical procedures or brain-penetrating electrodes, which limit addressable…
Cat-Vu H. Bui, Neethu Maliakal, Hasan Ulusan, Andreas Hierlemann + 2 more
'Fernando Cardes' 'Attila Kaszás'] Electrode designs and materials have become an increasingly important performance driver for microelectrode arrays, which are among the essential tools for cellular electrophysiology. Ongoing works have continuously innovated over a diverse range of electrode shapes, sizes, and…
Pingyu Wang, Eric G. Wu, Hasan Uluşan, A.J. Phillips + 10 more
Silicon-based planar microelectronics is a powerful tool for scalably recording and modulating neural activity at high spatiotemporal resolution, but it remains challenging to target neural structures in three dimensions (3D). We present a method for directly fabricating 3D arrays of tissue-penetrating microelectrodes…
Kejun Xie, Shaomin Zhang, Shurong Dong, Shijian Li + 6 more
'Kedi Xu' 'Wanke Chen' 'Wei guo' 'Jikui Luo' 'Zhaohui Wu'] In this paper, we present a portable wireless electrocorticography (ECoG) system. It uses a high resolution 32-channel flexible ECoG electrodes array to collect electrical signals of brain activities and to stimulate the lesions. Electronic circuits are…
Authors not listed
Understanding and controlling the microstructure of zinc (Zn) metal electrodeposits is critical for advancing the next generation of rechargeable Zn batteries. In this study, we develop microelectrode arrays to systematically investigate the relationship between current density, morphology, and Coulombic efficiency…
Jeffrey R. Naughton, Timothy Connolly, Juan A. Varela, Jaclyn Lundberg + 4 more
'Jaclyn Lundberg' 'Michael J. Burns' 'Thomas C. Chiles' 'John P. Christianson' 'Michael J. Naughton'] Recent progress in the study of the brain has been greatly facilitated by the development of new tools capable of minimally-invasive, robust coupling to neuronal assemblies. Two prominent examples are the…
Scott Greenhorn, Véronique Coizet, Victor Dupuit, Bruno Fernandez + 6 more
single units recording within subcortical layers Authors: ['Scott Greenhorn' 'Véronique Coizet' 'Victor Dupuit' 'Bruno Fernandez' 'Guillaume A. Brès' 'A. Claudel' 'Pierre Gasner' 'Jan Warnking' 'Emmanuel Barbier' 'Cécile Delacour'] Abstract. Current techniques of neuroimaging, including electrical devices, are either…
Gergely Márton, Péter Baracskay, B Cseri, B Plósz + 3 more
'Z. Fekete' 'A. Pongrácz'] - 1 Comparative Psychophysiology Department, Institute of Cognitive Neuroscience and Physiology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 2 Magyar Tudósok Blvd., H-1117, Budapest, Hungary - 2 MEMS Laboratory, Institute for Technical Physics and Materials Science…
Elisa Castagnola, Sanitta Thongpang, Mieko Hirabayashi, Giorgio Nava + 7 more
'Surabhi Nimbalkar' 'Tri Minh Nguyen' 'Sandra Lara Galindo' 'Alexis Oyawale' 'James Bunnell' 'Chet T. Moritz' 'Sam Kassegne'] Progress in real-time, simultaneous in vivo detection of multiple neurotransmitters will help accelerate advances in neuroscience research. The need for development of probes capable of stable…
Huiqing Zhao, Ruping Liu, Huiling Zhang, Peng Cao + 3 more
'Ye Li' 'Joseph Pancrazio'] Neural microelectrode is the important bridge of information exchange between the human body and machines. By recording and transmitting nerve signals with electrodes, people can control the external machines. At the same time, using electrodes to electrically stimulate nerve tissue, people…
Mustafa Şen
Here, we report a facile method for electro-addressable functionalization of a probe comprising of closely spaced three individually addressable carbon fiber electrodes for detection of nucleic acids. First, a multi electrode array probe comprising three adjacent carbon fiber electrodes was fabricated through pulling a…
Chih-Wei Chang, Jin-Chern Chiou
This paper presents the design and implementation of an integrated wireless microsystem platform that provides the possibility to support versatile implantable neural sensing devices in free laboratory rats. Inductive coupled coils with low dropout regulator design allows true long-term recording without limitation of…
Flávio Afonso Gonçalves Mourão, Leonardo de Oliveira Guarnieri, Paulo Aparecido Amaral Júnior, Vinícius Rezende Carvalho + 2 more
Electrophysiological recordings lead amongst the techniques that aim to investigate the dynamics of neural activity sampled from large neural ensembles. However, the financial costs associated with the state-of-the-art technology used to manufacture probes and multi-channel recording systems make these experiments…
Mihaly Kollo, Romeo R Racz, Mina-Elraheb S Hanna, Abdulmalik M Obaid + 7 more
Mammalian brains consist of 10s of millions to 100s of billions of neurons operating at millisecond time scales, of which current recording techniques only capture a tiny fraction. Recording techniques capable of sampling neural activity at such temporal resolution have been difficult to scale: The most intensively…
Gaurav Goyal, Yoonkey Nam
The primary hippocampal neurons from E-18 rat were cultured inside the closed polydimethylsiloxane (PDMS) microchannels of varying sizes. The effect of the channel geometry on the spatial and the temporal variations in the neural microenvironment was investigated by studying neural maturation and variation in the media…
Horacio Londoño‐Ramírez, Xiaohua Huang, Jordi Cools, Anna Chrzanowska + 8 more
'Anna Chrzanowska' 'Clément Brunner' 'Marco Ballini' 'Luis Hoffman' 'Soeren Steudel' 'Cédric Rolin' 'Carolina Mora Lopez' 'Jan Genoe' 'Sebastian Haesler'] Title: Abstract Electrode grids are used in neuroscience research and clinical practice to record electrical activity from the surface of the brain. However…
Romeo R Racz, Mihaly Kollo, Gabriella Racz, Ciprian Bulz + 9 more
High signal-to-noise, scalable and minimally invasive recording and stimulation of the nervous system in intact animals is of fundamental importance to advance the understanding of brain function. Extracellular electrodes are among the most powerful tools capable of interfacing with large neuronal populations^1–3^.…
Charles Osarinmwian
Particle aggregates are formed with viable yeast cells (Saccharomyces cerevisiae) and bacterial cells (Escherichia coli and Micrococcus luteus), and are assembled in an interdigitated-castelled microelectrode using positive dielectrophoresis with an alternating current sinusoidal voltage of 2-20 V peak-peak at 1 MHz.…
Mihály Vöröslakos, Peter C. Petersen, Balázs Vöröslakos, György Buzsáki
High-yield electrophysiological extracellular recording in freely moving rodents provides a unique window into the temporal dynamics of neural circuits. Recording from unrestrained animals is critical to investigate brain activity during natural behaviors. The use and implantation of high-channel-count silicon probes…
MD Ridwan Adib, Colm Barrett, Shane O'Sullivan, Anna Flynn + 3 more
Electrochemical biosensors have been extensively researched and employed across diverse fields from environmental monitoring to clinical diagnostics. The determination of biomarkers such as glucose and pH, which are crucial for the health and well-being of animals, has led to a widespread use of these specific…
Authors not listed
Carbon fiber has become the standard electrode material to study neuronal communication. For techniques such as single-cell amperometry at synapses and intracellular recordings of neurotransmitters in secretory vesicles, nanometric electrodes are required. The smaller electrode dimension also offers the added benefit…
Steven Linfield, Sylwester Gawinkowski, Wojciech Nogala
Recently, shot noise has been shown to be an inherent part of all charge transfer processes, leading to a practical limit of quantification of 2100 electrons (~0.34 fC) (Curr. Opin. Electrochem. 2020, 22, 170177). Attainable limits of quantification are made much larger by greater background currents and insufficient…
Adva Raz, Hila Gubi, Adam Cohen, Fernando Patolsky
Biomarkers detection have become essential in medical diagnostics and early detection of life-threatening diseases. Modern-day medicine relies heavily on painful and invasive tests, the extraction of large volumes of venous blood being the most common tool of biomarker detection. These tests are time-consuming…
Yuanmo Wang, Ajay Pradhan, Pankaj Gupta, Jörg Hanrieder + 2 more
Acetylcholine (ACh) is a critical neurotransmitter influencing various neurophysiological functions. Despite its significance, there is a lack of quantitative methods with adequate spatiotemporal resolution for recording single exocytotic efflux of ACh. In this study, we present an ultrafast amperometric ACh biosensor…