14 papers · ranked by Valyu relevance
Simone Bruno, Ruth J. Williams, Domitilla Del Vecchio
Epigenetic cell memory allows distinct gene expression patterns to persist in different cell types despite a common genotype. Although different patterns can be maintained by the concerted action of transcription factors (TFs), it was proposed that long-term persistence hinges on chromatin state. Here, we study how the…
Marcel-Joseph Yared, Yasemin Yoluç, Marjorie Catala, Carine Tisné + 2 more
As essential components of the cellular protein synthesis machineries, tRNAs undergo a tightly controlled biogenesis process, which include the incorporation of a large number of posttranscriptional chemical modifications. Maturation defaults resulting in lack of modifications in the tRNA core may lead to the…
Endres Puschner, Maik Ender, Steffen Becker, Christof Paar
Field Programmable Gate Arrays (FPGAs) are known for their reprogrammability that allows for post-manufacture circuitry changes. Nowadays, they are integral to a variety of systems including highsecurity applications such as aerospace and military systems. However, this reprogrammability also introduces significant…
Marcel-Joseph Yared, Yasemin Yoluç, Marjorie Catala, Carine Tisné + 2 more
As essential components of the protein synthesis machinery, tRNAs undergo a tightly controlled biogenesis process, which include the incorporation of numerous posttranscriptional modifications. Defects in these tRNA maturation steps may lead to the degradation of hypomodified tRNAs by the rapid tRNA decay (RTD) and…
Julia L. Reinsch, David M. Garcia
Saccharomyces cerevisiae is an invaluable model in the study of mitochondrial tRNA biology. Yet the positions of modified bases in all yeast mitochondrially-encoded tRNAs (mt-tRNAs) are still not fully mapped. We performed Nanopore direct RNA sequencing (DRS) on tRNAs from the crude mitochondrial fraction of yeast to…
Dmitry Kostrichkin, С. В. Руденко, Mihails Lapkis, Aigars Atvars
aRD820 Low-Noise Rail-to-Rail Operational Amplifier Authors: ['Dmitry Kostrichkin' 'С. В. Руденко' 'Mihails Lapkis' 'Aigars Atvars'] - The task of this work was to design and later produce a low-power (single supply 5 - 30 V, dual supply ±2.5 V and ±15 V) rail-to-rail operational amplifier aRD820 with low voltage noise…
Valerii Ostrovskii, Petr Fedoseev, Yulia Bobrova, Denis Butusov + 1 more
'Xianfu Wang'] This paper proposes a novel identification method for memristive devices using Knowm memristors as an example. The suggested identification method is presented as a generalized process for a wide range of memristive elements. An experimental setup was created to obtain a set of intrinsic I-V curves for…
Vaidhiswaran Ramesh, Thapanar Suwanmajo, J. Krishnan
Biochemical networks are at the heart of cellular information processing. These networks contain distinct facets: (i) processing of information from the environment via cascades/pathways along with network regulation and (ii) modification of substrates in different ways, to confer protein functionality, stability and…
Han Xin Huang, Gabriella M. Floro, Emmanuel Asare, Weichen Huang + 1 more
Transfer RNA (tRNA) modifications have been increasingly implicated as post-transcriptional regulators of basic neuronal functions. However, characterizing tRNA modification profiles in specific neural circuits that control well-defined behaviors is notoriously difficult due to the complexity of conventional…
Jinshui Zhang, Stefan M Goetz
—With their great scalability and flexibility, cascadedbridge and modular multilevel converters have enabled a variety of energy applications, such as offshore wind power, high-voltage dc power transmission, power-quality management, and cuttingedge medical instrumentation. The incorporation of parallel connectivity…
Ruhan Yang, Krithik Ranjan, Ellen Yi–Luen
This paper introduces a new method of paper circuit fabrication that overcomes design barriers and increases flexibility in circuit design. Conventional circuit boards rely on thin traces, which limits the complexity and accuracy when applied to paper circuits. To address this issue, we propose a method that uses large…
Olivia Gallup, Harrison Steel
In the past decades, a wide suite of design tools for biological systems have been developed, but using these to create biotechnologies that achieve reliable and predictable behaviour remains challenging. Modelling approaches have enabled researchers to traverse the vast search space of genetic circuits more…
Authors not listed
Molecular systems capable of directing the flow of excitons are key to the development and optimization of optoelectronic materials. The transport of excitons across multiple molecules is governed by the intermolecular electronic coupling network. In this manuscript, we consider the effects of complex-valued…
Authors not listed
Iontronics can improve soft robotics, like wearable devices and environmental sensors, by replacing rigid electronics with viscoelastic materials that mimic biological tissue. Circuit components, including diodes, transistors, and power sources, have been fabricated with soft materials that utilize ionic current.…