21 papers · ranked by Valyu relevance
Jun Zhuang, Lydia Ng, Derric Williams, Matthew Valley + 4 more
Visual perception and behavior are mediated by cortical areas that have been distinguished using architectonic and retinotopic criteria. We employed fluorescence imaging and GCaMP6 reporter mice to generate retinotopic maps, revealing additional regions of retinotopic organization that extend into barrel and…
Ulf H. Schnabel, Christophe Bossens, Jeannette A. M. Lorteije, Matthew W. Self + 2 more
'Matthew W. Self' 'Hans Op de Beeck' 'Pieter R. Roelfsema'] Figure-ground segregation is the process by which the visual system identifies image elements of figures and segregates them from the background. Previous studies examined figure-ground segregation in the visual cortex of monkeys where figures elicit stronger…
Dario L. Ringach, Patrick J. Mineault, Elaine Tring, Nicholas D. Olivas + 2 more
'Nicholas D. Olivas' 'Pablo Garcia-Junco-Clemente' 'Joshua T. Trachtenberg'] The primary visual cortex of higher mammals is organized into two-dimensional maps, where the preference of cells for stimulus parameters is arranged regularly on the cortical surface. In contrast, the preference of neurons in the rodent…
Declan P. Rowley, Madineh Sedigh-Sarvestani
The mouse has become one of the main organisms for studies of the visual system. As a result, there is increased effort to understand universal principles of visual processing by comparing the mouse visual system to that of other species. In primates and other well-studied species including cats and tree shrews, the…
Mai M. Morimoto, Emi Uchishiba, Aman B. Saleem
Context dependent top-down modulation in visual processing has been a topic of wide interest. Recent findings on context dependent modulation, combined with the tools available to investigate network mechanisms in the mouse, make the mouse primary visual cortex an ideal system to investigate context-dependent…
Christopher P. Burgess, Armin Lak, Nicholas A. Steinmetz, Peter Zatka-Haas + 11 more
'Peter Zatka-Haas' 'Charu Bai Reddy' 'Elina A.K. Jacobs' 'Jennifer F. Linden' 'Joseph J. Paton' 'Adam Ranson' 'Sylvia Schröder' 'Sofia Soares' 'Miles J. Wells' 'Lauren E. Wool' 'Kenneth D. Harris' 'Matteo Carandini'] Title: Summary Research in neuroscience increasingly relies on the mouse, a mammalian species that…
Asim Iqbal, Phil Dong, Christopher M. Kim, Heeun Jang
— Finding a code to unravel the population of neural responses that leads to a distinct animal behavior has been a longstanding question in the field of neuroscience. With the recent advances in machine learning, it is shown that the hierarchically Deep Neural Networks (DNNs) perform optimally in decoding unique…
Eve Ben Yehoshua, Hamutal Slovin
Recently, mice became a popular research model for the visual system including objects processing. However, while primates use their fovea to inspect objects at high resolution, mice have low visual acuity and lack a foveal region. Thus, how objects are encoded in the visual cortex of mice and whether monkeys and mice…
Christopher P Burgess, Armin Lak, Nicholas A Steinmetz, Peter Zatka-Haas + 11 more
Research in neuroscience relies increasingly on the mouse, a mammalian species that affords unparalleled genetic tractability and brain atlases. Here we introduce high-yield methods for probing mouse visual decisions. Mice are head-fixed, which facilitates repeatable visual stimulation, eye tracking, and brain access.…
Guillaume Laliberté, Rahmeh Othman, Elvire Vaucher
The cholinergic potentiation of visual conditioning enhances visual acuity and discrimination of the trained stimulus. To determine if this also induces long-term plastic changes on cortical maps and connectivity in the visual cortex and higher associative areas, mesoscopic calcium imaging was performed in head-fixed…
O. Bibollet-Bahena, S. Tissier, S. Ho-Tran, A. Rojewski + 1 more
'C. Casanova'] Optimal conditions of development have been of interest for decades, since genetics alone cannot fully explain how an individual matures. In the present study, we used optical brain imaging to investigate whether a relatively simple enrichment can positively influence the development of the visual cortex…
Nana Nishio, Hiroaki Tsukano, Ryuichi Hishida, Manabu Abe + 5 more
'Junichi Nakai' 'Meiko Kawamura' 'Atsushi Aiba' 'Kenji Sakimura' 'Katsuei Shibuki'] The visual cortex of mice is a useful model for investigating the mammalian visual system. In primates, higher visual areas are classified into two parts, the dorsal stream (“where” pathway) and ventral stream (“what” pathway). The…
Liwei Huang, Zhengyu Ma, Liutao Yu, Huihui Zhou + 1 more
Deep artificial neural networks (ANNs) play a major role in modeling the visual pathways of primate and rodent. However, they highly simplify the computational properties of neurons compared to their biological counterparts. Instead, Spiking Neural Networks (SNNs) are more biologically plausible models since spiking…
Thi Ngoc Anh Dinh, Won Beom Jung, Hyun-Ji Shim, Seong-Gi Kim
The functional characteristics of the mouse visual system have not previously been well explored using fMRI. In this research, we examined 9.4 T BOLD fMRI responses to visual stimuli of varying pulse durations (1 – 50 ms) and temporal frequencies (1 – 10 Hz) under ketamine and xylazine anesthesia, and compared fMRI…
Nikos Melanitis, Konstantina S. Nikita
Visual attention forms the basis of understanding the visual world. In this work we follow a computational approach to investigate the biological basis of visual attention. We analyze retinal and cortical electrophysiological data from mouse. Visual Stimuli are Natural Images depicting real world scenes. Our results…
Simon Weiler, Vahid Rahmati, Marcel Isstas, Johann Wutke + 9 more
Tactile sensation and vision are often both utilized for the exploration of objects that are within reach though it is not known whether or how these two distinct sensory systems might combine such information. Here in mice we find that stimulation of the contralateral whisker array suppresses visually evoked activity…
Elaine Tring, Dario L. Ringach
In cat visual cortex, the response of a neural population to the linear combination of two sinusoidal gratings (a plaid) can be well approximated by a weighted sum of the population responses to the individual gratings — a property we refer to as subspace invariance. We tested subspace invariance in mouse primary…
Manuel Schottdorf, Wolfgang W. Keil, David M. Coppola, Leonard White + 1 more
'Fred Wolf'] The architecture of iso-orientation domains in the primary visual cortex (V1) of placental carnivores and primates apparently follows species invariant quantitative laws. Dynamical optimization models assuming that neurons coordinate their stimulus preferences throughout cortical circuits linking millions…
Rino Saiga, Kiyoto Shiga, Yasuhiro Maruta, Chie Inomoto + 18 more
human and mouse neurons and their implementation in generative AIs Authors: ['Rino Saiga' 'Kiyoto Shiga' 'Yasuhiro Maruta' 'Chie Inomoto' 'Hiroshi Kajiwara' 'Naoya Nakamura' 'Yu Kakimoto' 'Yoshiro Yamamoto' 'Masahiro Yasutake' 'Masayuki Uesugi' 'Akihisa Takeuchi' 'Kentaro Uesugi' 'Yasuko Terada' 'Yoshio Suzuki' 'Viktor…
Authors not listed
This paper formally defines an operational isomorphism between spectral damping in molecular vibronic systems and neuromodulatory control in biological sensory systems. Without asserting causal continuity or physical identity across scales, we show that both domains instantiate the same class of output-selective…
Authors not listed
Imaging small polar metabolites and analyzing their in vivo dynamics with stable isotope labeled (SIL) tracing through various biochemical pathways, including citric acid (TCA) cycle, glycolysis, and amino acid metabolism, has gained substantial interest over the years. However, imaging these small polar metabolites…