20 papers · ranked by Valyu relevance
J. A. Scott Kelso
Multistable coordination dynamics exists at many levels, from multifunctional neural circuits in vertebrates and invertebrates to large-scale neural circuitry in humans. Moreover, multistability spans (at least) the domains of action and perception, and has been found to place constraints upon, even dictating the…
Frank Freyer, James A. Roberts, Petra Ritter, Michael Breakspear + 1 more
'Tim Behrens'] Multistability and scale-invariant fluctuations occur in a wide variety of biological organisms from bacteria to humans as well as financial, chemical and complex physical systems. Multistability refers to noise driven switches between multiple weakly stable states. Scale-invariant fluctuations arise…
Burhanuddin Sabuwala, Kishore Hari, S V Abhishek, Mohit Kumar Jolly
Multistability is central to biological systems as it plays a key role in adaptation, evolvability, and differentiation. Multistability can be achieved by integrating positive feedback loops into the regulation. The simplest of such feedback loops are a) a mutual inhibition (MI) loop, b) a mutual activation (MA) loop…
Veronika Dubinkina, Yulia Fridman, Parth Pratim Pandey, Sergei Maslov
Microbial communities routinely have several possible species compositions or community states observed for the same environmental parameters. Changes in these parameters can trigger abrupt and persistent transitions (regime shifts) between such community states. Yet little is known about the main determinants and…
A. Anzo-Hernández, H. E. Gilardi-Velázquez, E. Campos-Cantón
We present a dissipative system with unstable dynamics called unstable dissipative system which are capable of generating a multi-stable behavior, i.e., depending on its initial condition the trajectory of the system converge to a specific basin of attraction. A piecewise linear (PWL) systems is generated based on…
Bóris Marin, William H. Barnett, Anca Doloc-Mihu, Ronald L. Calabrese + 2 more
'Ronald L. Calabrese' 'Gennady S. Cymbalyuk' 'Bard Ermentrout'] Flexibility in neuronal circuits has its roots in the dynamical richness of their neurons. Depending on their membrane properties single neurons can produce a plethora of activity regimes including silence, spiking and bursting. What is less appreciated is…
Veronika Dubinkina, Yulia Fridman, Parth Pratim Pandey, Sergei Maslov + 2 more
'Sergei Maslov' 'Wenying Shou' 'Ian T Baldwin'] Microbial communities routinely have several possible species compositions or community states observed for the same environmental parameters. Changes in these parameters can trigger abrupt and persistent transitions (regime shifts) between such community states. Yet…
Guim Aguadé-Gorgorió, Jean-François Arnoldi, Matthieu Barbier, Sonia Kéfi
Many natural and man-made systems, from financial markets to ecosystems or the human brain, are built from multiple interconnected units. This complex high-dimensionality hinders our capacity to understand and predict the dynamics, functioning and fragility of these systems. One fragility scenario, particularly…
Chiranjit Mitra, Jürgen Kurths, Reik V. Donner
The abundance of multistable dynamical systems calls for an appropriate quantification of the respective stability of the (stable) states of such systems. Motivated by the concept of ecological resilience, we propose a novel and pragmatic measure called ‘integral stability’ which integrates different aspects commonly…
Juken Hong, Wenzhi Xue, Teng Wang
Microbial communities living in the same environment often display multiple alternative stable states, each characterized by a unique composition of species. Understanding the origin and determinants of microbiome multistability has broad implications in environments, human health and microbiome engineering. However…
Jordan Breffle, Subhadra Mokashe, Siwei Qiu, Paul Miller
Neural circuits with multiple discrete attractor states could support a variety of cognitive tasks according to both empirical data and model simulations. We assess the conditions for such multistability in neural systems, using a firing-rate model framework, in which clusters of neurons with net self-excitation are…
Chiranjit Mitra, Anshul Choudhary, Sudeshna Sinha, Jürgen Kurths + 1 more
'Reik V. Donner'] Dynamical entities interacting with each other on complex networks often exhibit multistability. The stability of a desired steady regime (e.g., a synchronized state) to large perturbations is critical in the operation of many real-world networked dynamical systems such as ecosystems, power grids, the…
Heather A. Harrington, Elisenda Feliu, Carsten Wiuf, Michael M. P. Stumpf
'Michael M. P. Stumpf'] Many biological, physical, and social interactions have a particular dependence on where they take place. In living cells, protein movement between the nucleus and cytoplasm affects cellular response (i.e., proteins must be present in the nucleus to regulate their target genes). Here we use…
Feng Liu, Zhi‐Hong Guan
In this paper, we present a unified framework of multiple attractors including multistability, multiperiodicity and multichaos. Multichaos, which means that the chaotic solution of a system lies in different disjoint invariant sets with respect to different initial values, is a very interesting and important dynamical…
Anastasiya V. Pimenova, Denis S. Goldobin
For self-sustained oscillators subject to noise the coherence, understood as a constancy of the instantaneous oscillation frequency, is one of the primary characteristics. The delayed feedback has been previously revealed to be an efficient tool for controlling coherence of noise-driven self-sustained oscillator. The…
Xiaoxian Tang, Hao Xu
For three typical sets of small reaction networks (networks with two reactions, one irreversible and one reversible reaction, or two reversible-reaction pairs), we completely answer the challenging question: what is the smallest subset of all multistable networks such that any multistable network outside of the subset…
Kasper Tolborg, Johan Klarbring, Alex M. Ganose, Aron Walsh
What is the likelihood that a hypothetical material - the combination of a composition and crystal structure - can be formed? Underpinning the reliability of predictions for local or global crystal stability is the choice of thermodynamic potential. Here, we discuss recent advances in free energy descriptions for…
Christopher Walker, Garrett Meek, Theodore Fobe, Michael R. Shirts
We describe a process to build and simulate coarse-grained oligomers using temperature replica exchange molecular dynamics and analyze them for thermodynamic and structural characteristics of cooperative folding transitions. We also introduce a Python package (cg_openmm) to carry out these simulations and analyses. We…
Authors not listed
Multi-material 3D printing concerns the use of two or more 3D printable materials within a single printed part. The result is a composite that benefits from the combined properties of the individual 3D printed materials. Typically, a distinct differentiation between material properties can only be achieved using…
Yoshiharu Mukouyama, Kenya Tanaka, Shuji Nakanishi, Yoshihiro Nakato
The present work reveals that a prebiotic chemical system can generate self-organizing ability that leads to highly ordered structures and an active character such as free independent harmonious behavior. This result is the properties of natural things that have long been overlooked since Darwin’s theory of evolution…